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Hemolytic Uremic Syndrome
R. Brooke Jeffrey, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Hemolytic uremic syndrome (HUS)
              • Definitions

                • Triad of acute hemolytic anemia, acute renal failure, and thrombocytopenia

              IMAGING

              • General Features

                • Imaging Recommendations

                  • Radiographic Findings

                    • CT Findings

                      • MR Findings

                        • Ultrasonographic Findings

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Ahn CK et al: Shiga-toxin producing Escherichia coli and the hemolytic uremic syndrome: what have we learned in the past 25 years? Adv Exp Med Biol. 634:1-17, 2009
                                            2. Bitzan M: Treatment options for HUS secondary to Escherichia coli O157:H7. Kidney Int Suppl. (112):S62-6, 2009
                                            3. Clark WF: HUS/TTP update: 2008. Kidney Int Suppl. (112):S1-3, 2009
                                            4. Heffernan E et al: Escherichia coli 0157 enterohaemorrhagic colitis associated with pyelonephritis: CT findings. Br J Radiol. 82(976):e63-6, 2009
                                            5. Tarr PI: Shiga toxin-associated hemolytic uremic syndrome and thrombotic thrombocytopenic purpura: distinct mechanisms of pathogenesis. Kidney Int Suppl. (112):S29-32, 2009
                                            6. Toldo I et al: Diffusion-weighted imaging findings in hemolytic uremic syndrome with central nervous system involvement. J Child Neurol. 24(2):247-50, 2009
                                            7. d'Almeida M et al: Bowel wall thickening in children: CT findings. Radiographics. 28(3):727-46, 2008
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Abbreviations

                                                          • Hemolytic uremic syndrome (HUS)
                                                        • Definitions

                                                          • Triad of acute hemolytic anemia, acute renal failure, and thrombocytopenia

                                                        IMAGING

                                                        • General Features

                                                          • Imaging Recommendations

                                                            • Radiographic Findings

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Ultrasonographic Findings

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Ahn CK et al: Shiga-toxin producing Escherichia coli and the hemolytic uremic syndrome: what have we learned in the past 25 years? Adv Exp Med Biol. 634:1-17, 2009
                                                                                      2. Bitzan M: Treatment options for HUS secondary to Escherichia coli O157:H7. Kidney Int Suppl. (112):S62-6, 2009
                                                                                      3. Clark WF: HUS/TTP update: 2008. Kidney Int Suppl. (112):S1-3, 2009
                                                                                      4. Heffernan E et al: Escherichia coli 0157 enterohaemorrhagic colitis associated with pyelonephritis: CT findings. Br J Radiol. 82(976):e63-6, 2009
                                                                                      5. Tarr PI: Shiga toxin-associated hemolytic uremic syndrome and thrombotic thrombocytopenic purpura: distinct mechanisms of pathogenesis. Kidney Int Suppl. (112):S29-32, 2009
                                                                                      6. Toldo I et al: Diffusion-weighted imaging findings in hemolytic uremic syndrome with central nervous system involvement. J Child Neurol. 24(2):247-50, 2009
                                                                                      7. d'Almeida M et al: Bowel wall thickening in children: CT findings. Radiographics. 28(3):727-46, 2008