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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Hepatic adenoma (HA)
Synonyms
- Hepatocellular adenoma, liver cell adenoma
Definitions
- Heterogeneous group of benign hepatocellular neoplasms with distinctive genetic, pathologic, and clinical features
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Costa AF et al: Benign neoplasms, mass-like infections, and pseudotumors that mimic hepatic malignancy at MRI. J Magn Reson Imaging.53(4):979-94, 2021
- Auer TA et al: Hepatocellular adenomas: is there additional value in using Gd-EOB-enhanced MRI for subtype differentiation? Eur Radiol. 30(6):3497-506, 2020
- Bise S et al: New MRI features improve subtype classification of hepatocellular adenoma. Eur Radiol. 29(5):2436-47, 2019
- Bisig AM et al: Classics in abdominal imaging: the atoll sign. Abdom Radiol (NY). 44(4):1621-2, 2019
- Cannella R et al: Value of texture analysis on gadoxetic acid-enhanced MRI for differentiating hepatocellular adenoma from focal nodular hyperplasia. AJR Am J Roentgenol. 212(3):538-46, 2019
- Cogley JR et al: MR imaging of benign focal liver lesions. Radiol Clin North Am. 52(4):657-82, 2014
- De Kock I et al: Hepatic adenomatosis: MR imaging features. JBR-BTR. 97(2):105-8, 2014
- Grazioli L et al: Hepatocellular adenoma and focal nodular hyperplasia: value of gadoxetic acid-enhanced MR imaging in differential diagnosis. Radiology. 262(2):520-9, 2012
- Katabathina VS et al: Genetics and imaging of hepatocellular adenomas: 2011 update. Radiographics. 31(6):1529-43, 2011
- Mounajjed T et al: Telangiectatic variant of hepatic adenoma: clinicopathologic features and correlation between liver needle biopsy and resection. Am J Surg Pathol. 35(9):1356-63, 2011
- Ji HF et al: Reduced-size liver transplantation for glycogen storage disease. Hepatobiliary Pancreat Dis Int. 8(1):106-8, 2009
- Kobayashi S et al: Radiological and histopathological manifestations of hepatocellular nodular lesions concomitant with various congenital and acquired hepatic hemodynamic abnormalities. Jpn J Radiol. 27(2):53-68, 2009
- Santambrogio R et al: Liver transplantation for spontaneous intrapartum rupture of a hepatic adenoma. Obstet Gynecol. 113(2 Pt 2):508-10, 2009
- Furlan A et al: Multiple hepatic adenomas associated with liver steatosis at CT and MRI: a case-control study. AJR Am J Roentgenol. 191(5):1430-5, 2008
- Prasad SR et al: Fat-containing lesions of the liver: radiologic-pathologic correlation. Radiographics. 25(2):321-31, 2005
- Grazioli L et al: Hepatic adenomas: imaging and pathologic findings. Radiographics. 21(4):877-92; discussion 892-4, 2001
- Grazioli L et al: Liver adenomatosis: clinical, histopathologic, and imaging findings in 15 patients. Radiology. 216(2):395-402, 2000
- Ichikawa T et al: Hepatocellular adenoma: multiphasic CT and histopathologic findings in 25 patients. Radiology. 214(3):861-8, 2000
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Hepatic adenoma (HA)
Synonyms
- Hepatocellular adenoma, liver cell adenoma
Definitions
- Heterogeneous group of benign hepatocellular neoplasms with distinctive genetic, pathologic, and clinical features
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Costa AF et al: Benign neoplasms, mass-like infections, and pseudotumors that mimic hepatic malignancy at MRI. J Magn Reson Imaging.53(4):979-94, 2021
- Auer TA et al: Hepatocellular adenomas: is there additional value in using Gd-EOB-enhanced MRI for subtype differentiation? Eur Radiol. 30(6):3497-506, 2020
- Bise S et al: New MRI features improve subtype classification of hepatocellular adenoma. Eur Radiol. 29(5):2436-47, 2019
- Bisig AM et al: Classics in abdominal imaging: the atoll sign. Abdom Radiol (NY). 44(4):1621-2, 2019
- Cannella R et al: Value of texture analysis on gadoxetic acid-enhanced MRI for differentiating hepatocellular adenoma from focal nodular hyperplasia. AJR Am J Roentgenol. 212(3):538-46, 2019
- Cogley JR et al: MR imaging of benign focal liver lesions. Radiol Clin North Am. 52(4):657-82, 2014
- De Kock I et al: Hepatic adenomatosis: MR imaging features. JBR-BTR. 97(2):105-8, 2014
- Grazioli L et al: Hepatocellular adenoma and focal nodular hyperplasia: value of gadoxetic acid-enhanced MR imaging in differential diagnosis. Radiology. 262(2):520-9, 2012
- Katabathina VS et al: Genetics and imaging of hepatocellular adenomas: 2011 update. Radiographics. 31(6):1529-43, 2011
- Mounajjed T et al: Telangiectatic variant of hepatic adenoma: clinicopathologic features and correlation between liver needle biopsy and resection. Am J Surg Pathol. 35(9):1356-63, 2011
- Ji HF et al: Reduced-size liver transplantation for glycogen storage disease. Hepatobiliary Pancreat Dis Int. 8(1):106-8, 2009
- Kobayashi S et al: Radiological and histopathological manifestations of hepatocellular nodular lesions concomitant with various congenital and acquired hepatic hemodynamic abnormalities. Jpn J Radiol. 27(2):53-68, 2009
- Santambrogio R et al: Liver transplantation for spontaneous intrapartum rupture of a hepatic adenoma. Obstet Gynecol. 113(2 Pt 2):508-10, 2009
- Furlan A et al: Multiple hepatic adenomas associated with liver steatosis at CT and MRI: a case-control study. AJR Am J Roentgenol. 191(5):1430-5, 2008
- Prasad SR et al: Fat-containing lesions of the liver: radiologic-pathologic correlation. Radiographics. 25(2):321-31, 2005
- Grazioli L et al: Hepatic adenomas: imaging and pathologic findings. Radiographics. 21(4):877-92; discussion 892-4, 2001
- Grazioli L et al: Liver adenomatosis: clinical, histopathologic, and imaging findings in 15 patients. Radiology. 216(2):395-402, 2000
- Ichikawa T et al: Hepatocellular adenoma: multiphasic CT and histopathologic findings in 25 patients. Radiology. 214(3):861-8, 2000
