Malignant spread of neoplasm to hepatic parenchyma
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Burrowes DP et al: RadioGraphics update: contrast-enhanced US approach to the diagnosis of focal liver masses. Radiographics. 40(4):E16-20, 2020
Haj-Mirzaian A et al: Updates on imaging of liver tumors. Curr Oncol Rep. 22(5):46, 2020
Schneider J et al: Is liver ultrasound useful as part of the surveillance strategy following potentially curative colorectal cancer resection? Dig Dis. 37(3):234-8, 2019
Burrowes DP et al: Contrast-enhanced US approach to the diagnosis of focal liver masses. Radiographics. 37(5):1388-400, 2017
Expert Panel on Gastrointestinal Imaging et al: ACR Appropriateness Criteria® Suspected Liver Metastases. J Am Coll Radiol. 14(5S):S314-25, 2017
Sofue K et al: Does Gadoxetic acid-enhanced 3.0T MRI in addition to 64-detector-row contrast-enhanced CT provide better diagnostic performance and change the therapeutic strategy for the preoperative evaluation of colorectal liver metastases? Eur Radiol. 24(10):2532-9, 2014
Westwood M et al: Contrast-enhanced ultrasound using SonoVue® (sulphur hexafluoride microbubbles) compared with contrast-enhanced computed tomography and contrast-enhanced magnetic resonance imaging for the characterisation of focal liver lesions and detection of liver metastases: a systematic review and cost-effectiveness analysis. Health Technol Assess. 17(16):1-243, 2013
Salvatore V et al: Contrast-enhanced ultrasound for liver imaging: recent advances. Curr Pharm Des. 18(15):2236-52, 2012
Schulz A et al: Impact of contrast-enhanced intraoperative ultrasound on operation strategy in case of colorectal liver metastasis. Acta Radiol. 53(10):1081-7, 2012
Takahashi M et al: Contrast-enhanced intraoperative ultrasonography using perfluorobutane microbubbles for the enumeration of colorectal liver metastases. Br J Surg. 99(9):1271-7, 2012
Leen E et al: Potential value of contrast-enhanced intraoperative ultrasonography during partial hepatectomy for metastases: an essential investigation before resection? Ann Surg. 243(2):236-40, 2006
Oktar SO et al: Doppler sonographic evaluation of hemodynamic changes in colorectal liver metastases relative to liver size. J Ultrasound Med. 25(5):575-82, 2006
Rafaelsen SR et al: Ultrasound imaging of flow patterns in liver metastases from colorectal cancer. Scand J Gastroenterol. 39(8):761-5, 2004
von Herbay A et al: Real-time imaging with the sonographic contrast agent SonoVue: differentiation between benign and malignant hepatic lesions. J Ultrasound Med. 23(12):1557-68, 2004
Eberhardt SC et al: Utility of sonography for small hepatic lesions found on computed tomography in patients with cancer. J Ultrasound Med. 22(4):335-43; quiz 345-6, 2003
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
Malignant spread of neoplasm to hepatic parenchyma
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Burrowes DP et al: RadioGraphics update: contrast-enhanced US approach to the diagnosis of focal liver masses. Radiographics. 40(4):E16-20, 2020
Haj-Mirzaian A et al: Updates on imaging of liver tumors. Curr Oncol Rep. 22(5):46, 2020
Schneider J et al: Is liver ultrasound useful as part of the surveillance strategy following potentially curative colorectal cancer resection? Dig Dis. 37(3):234-8, 2019
Burrowes DP et al: Contrast-enhanced US approach to the diagnosis of focal liver masses. Radiographics. 37(5):1388-400, 2017
Expert Panel on Gastrointestinal Imaging et al: ACR Appropriateness Criteria® Suspected Liver Metastases. J Am Coll Radiol. 14(5S):S314-25, 2017
Sofue K et al: Does Gadoxetic acid-enhanced 3.0T MRI in addition to 64-detector-row contrast-enhanced CT provide better diagnostic performance and change the therapeutic strategy for the preoperative evaluation of colorectal liver metastases? Eur Radiol. 24(10):2532-9, 2014
Westwood M et al: Contrast-enhanced ultrasound using SonoVue® (sulphur hexafluoride microbubbles) compared with contrast-enhanced computed tomography and contrast-enhanced magnetic resonance imaging for the characterisation of focal liver lesions and detection of liver metastases: a systematic review and cost-effectiveness analysis. Health Technol Assess. 17(16):1-243, 2013
Salvatore V et al: Contrast-enhanced ultrasound for liver imaging: recent advances. Curr Pharm Des. 18(15):2236-52, 2012
Schulz A et al: Impact of contrast-enhanced intraoperative ultrasound on operation strategy in case of colorectal liver metastasis. Acta Radiol. 53(10):1081-7, 2012
Takahashi M et al: Contrast-enhanced intraoperative ultrasonography using perfluorobutane microbubbles for the enumeration of colorectal liver metastases. Br J Surg. 99(9):1271-7, 2012
Leen E et al: Potential value of contrast-enhanced intraoperative ultrasonography during partial hepatectomy for metastases: an essential investigation before resection? Ann Surg. 243(2):236-40, 2006
Oktar SO et al: Doppler sonographic evaluation of hemodynamic changes in colorectal liver metastases relative to liver size. J Ultrasound Med. 25(5):575-82, 2006
Rafaelsen SR et al: Ultrasound imaging of flow patterns in liver metastases from colorectal cancer. Scand J Gastroenterol. 39(8):761-5, 2004
von Herbay A et al: Real-time imaging with the sonographic contrast agent SonoVue: differentiation between benign and malignant hepatic lesions. J Ultrasound Med. 23(12):1557-68, 2004
Eberhardt SC et al: Utility of sonography for small hepatic lesions found on computed tomography in patients with cancer. J Ultrasound Med. 22(4):335-43; quiz 345-6, 2003
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