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Hepatic Schistosomiasis
Atif Zaheer, MD; Michael P. Federle, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Bilharzia, bilharziasis, blood fluke
            • Definitions

              • Hepatic parasitic infestation by Schistosoma species causing periportal fibrosis and cirrhosis from deposition of eggs in small portal venules

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Lima LMSTB et al: Evaluation of hepatic fibrosis by elastography in patients with schistosomiasis mansoni. Trans R Soc Trop Med Hyg. 114(7):531-7, 2020
                                          2. Mamone G et al: Hepatic morphology abnormalities: beyond cirrhosis. Abdom Radiol (NY). 43(7):1612-26, 2018
                                          3. Lambertucci JR: Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools. Rev Soc Bras Med Trop. 47(2):130-6, 2014
                                          4. Li Y et al: Severe hepatosplenic schistosomiasis: clinicopathologic study of 102 cases undergoing splenectomy. Hum Pathol. 42(1):111-9, 2011
                                          5. Silva CC et al: Schistosomiasis mansoni: ultrasound-evaluated hepatic fibrosis and serum concentrations of hyaluronic acid. Ann Trop Med Parasitol. 105(3):233-9, 2011
                                          6. Voieta I et al: Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study. Mem Inst Oswaldo Cruz. 105(4):414-21, 2010
                                          7. Fung HS et al: Hepatic schistosomiasis. Hong Kong Med J. 15(1):75-6, 2009
                                          8. Horiuchi A et al: Hepatic ultrasound appearance and colonoscopic finding of schistosomiasis japonica. Clin Gastroenterol Hepatol. 6(11):A24, 2008
                                          9. Mortele KJ et al: The infected liver: radiologic-pathologic correlation. Radiographics. 24(4):937-55, 2004
                                          10. Richter J et al: Ultrasound in tropical and parasitic diseases. Lancet. 362(9387):900-2, 2003
                                          11. Ross AG et al: Schistosomiasis. N Engl J Med. 346(16):1212-20, 2002
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Synonyms

                                                      • Bilharzia, bilharziasis, blood fluke
                                                    • Definitions

                                                      • Hepatic parasitic infestation by Schistosoma species causing periportal fibrosis and cirrhosis from deposition of eggs in small portal venules

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Lima LMSTB et al: Evaluation of hepatic fibrosis by elastography in patients with schistosomiasis mansoni. Trans R Soc Trop Med Hyg. 114(7):531-7, 2020
                                                                                  2. Mamone G et al: Hepatic morphology abnormalities: beyond cirrhosis. Abdom Radiol (NY). 43(7):1612-26, 2018
                                                                                  3. Lambertucci JR: Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools. Rev Soc Bras Med Trop. 47(2):130-6, 2014
                                                                                  4. Li Y et al: Severe hepatosplenic schistosomiasis: clinicopathologic study of 102 cases undergoing splenectomy. Hum Pathol. 42(1):111-9, 2011
                                                                                  5. Silva CC et al: Schistosomiasis mansoni: ultrasound-evaluated hepatic fibrosis and serum concentrations of hyaluronic acid. Ann Trop Med Parasitol. 105(3):233-9, 2011
                                                                                  6. Voieta I et al: Imaging techniques and histology in the evaluation of liver fibrosis in hepatosplenic schistosomiasis mansoni in Brazil: a comparative study. Mem Inst Oswaldo Cruz. 105(4):414-21, 2010
                                                                                  7. Fung HS et al: Hepatic schistosomiasis. Hong Kong Med J. 15(1):75-6, 2009
                                                                                  8. Horiuchi A et al: Hepatic ultrasound appearance and colonoscopic finding of schistosomiasis japonica. Clin Gastroenterol Hepatol. 6(11):A24, 2008
                                                                                  9. Mortele KJ et al: The infected liver: radiologic-pathologic correlation. Radiographics. 24(4):937-55, 2004
                                                                                  10. Richter J et al: Ultrasound in tropical and parasitic diseases. Lancet. 362(9387):900-2, 2003
                                                                                  11. Ross AG et al: Schistosomiasis. N Engl J Med. 346(16):1212-20, 2002