Bookmarks
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Hepatocellular carcinoma (HCC)
Synonyms
- Hepatoma, primary liver cancer
Definitions
- Malignant neoplasm originating from hepatocytes
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
- Burrowes DP et al: Characterization of focal liver masses: a multicenter comparison of contrast-enhanced ultrasound, computed tomography, and magnetic resonance imaging. J Ultrasound Med. ePub, 2021
- Kamaya A et al: HCC screening: is ultrasound still needed at transplant centers?-point: yes, ultrasound remains first line. AJR Am J Roentgenol. 216(3):579-80, 2021
- Burrowes DP et al: RadioGraphics update: contrast-enhanced US approach to the diagnosis of focal liver masses. Radiographics. 40(4):E16-20, 2020
- Rodgers SK et al: Role of US LI-RADS in the LI-RADS algorithm. Radiographics. 39(3):690-708, 2019
- ACR Committee on LI-RADS (Liver): Liver Imaging & Reporting Data System (LI-RADS) v2018. http://www.acr.org/quality-safety/resources/LIRADS
- Chernyak V et al: Liver Imaging Reporting and Data System (LI-RADS) version 2018: imaging of hepatocellular carcinoma in at-risk patients. Radiology. 289(3):816-30, 2018
- Tang A et al: Epidemiology of hepatocellular carcinoma: target population for surveillance and diagnosis. Abdom Radiol (NY). 43(1):13-25, 2018
- ACR Committee on Ultrasound LI-RADS: Ultrasound LI-RADS v2017. https://www.acr.org/Clinical-Resources/Reporting-and-Data-Systems/LI-RADS/Ultrasound-LI-RADS-v2017
- OPTN: Adult MELD Exceptions for Hepatocellular Carcinoma (HCC). https://optn.transplant.hrsa.gov/media/2846/liver_guidance_hcc_201706.pdf
- Davarpanah AH et al: The role of imaging in hepatocellular carcinoma: the present and future. J Clin Gastroenterol. 47 Suppl:S7-10, 2013
- Liu YI et al: Quantitatively defining washout in hepatocellular carcinoma. AJR Am J Roentgenol. 200(1):84-9, 2013
- Niu Y et al: Contrast-enhanced ultrasonography for the diagnosis of small hepatocellular carcinoma: a meta-analysis and meta-regression analysis. Tumour Biol. 34(6):3667-74, 2013
- McEvoy SH et al: Hepatocellular carcinoma: illustrated guide to systematic radiologic diagnosis and staging according to guidelines of the American Association for the Study of Liver Diseases. Radiographics. 33(6):1653-68, 2013
- Patel M et al: Hepatocellular carcinoma: diagnostics and screening. J Eval Clin Pract. 18(2):335-42, 2012
- Maturen KE et al: Posterior acoustic enhancement in hepatocellular carcinoma. J Ultrasound Med. 30(4):495-9, 2011
- Murakami T et al: Ultrasonography, computed tomography and magnetic resonance imaging of hepatocellular carcinoma: toward improved treatment decisions. Oncology. 81 Suppl 1:86-99, 2011
- Lencioni R: Surveillance and early diagnosis of hepatocellular carcinoma. Dig Liver Dis. 42 Suppl 3:S223-7, 2010
- Kamaya A et al: Hypervascular liver lesions. Semin Ultrasound CT MR. 30(5):387-407, 2009
- Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases
Related Anatomy
Loading...
Related Differential Diagnoses
Loading...
References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Hepatocellular carcinoma (HCC)
Synonyms
- Hepatoma, primary liver cancer
Definitions
- Malignant neoplasm originating from hepatocytes
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
- Burrowes DP et al: Characterization of focal liver masses: a multicenter comparison of contrast-enhanced ultrasound, computed tomography, and magnetic resonance imaging. J Ultrasound Med. ePub, 2021
- Kamaya A et al: HCC screening: is ultrasound still needed at transplant centers?-point: yes, ultrasound remains first line. AJR Am J Roentgenol. 216(3):579-80, 2021
- Burrowes DP et al: RadioGraphics update: contrast-enhanced US approach to the diagnosis of focal liver masses. Radiographics. 40(4):E16-20, 2020
- Rodgers SK et al: Role of US LI-RADS in the LI-RADS algorithm. Radiographics. 39(3):690-708, 2019
- ACR Committee on LI-RADS (Liver): Liver Imaging & Reporting Data System (LI-RADS) v2018. http://www.acr.org/quality-safety/resources/LIRADS
- Chernyak V et al: Liver Imaging Reporting and Data System (LI-RADS) version 2018: imaging of hepatocellular carcinoma in at-risk patients. Radiology. 289(3):816-30, 2018
- Tang A et al: Epidemiology of hepatocellular carcinoma: target population for surveillance and diagnosis. Abdom Radiol (NY). 43(1):13-25, 2018
- ACR Committee on Ultrasound LI-RADS: Ultrasound LI-RADS v2017. https://www.acr.org/Clinical-Resources/Reporting-and-Data-Systems/LI-RADS/Ultrasound-LI-RADS-v2017
- OPTN: Adult MELD Exceptions for Hepatocellular Carcinoma (HCC). https://optn.transplant.hrsa.gov/media/2846/liver_guidance_hcc_201706.pdf
- Davarpanah AH et al: The role of imaging in hepatocellular carcinoma: the present and future. J Clin Gastroenterol. 47 Suppl:S7-10, 2013
- Liu YI et al: Quantitatively defining washout in hepatocellular carcinoma. AJR Am J Roentgenol. 200(1):84-9, 2013
- Niu Y et al: Contrast-enhanced ultrasonography for the diagnosis of small hepatocellular carcinoma: a meta-analysis and meta-regression analysis. Tumour Biol. 34(6):3667-74, 2013
- McEvoy SH et al: Hepatocellular carcinoma: illustrated guide to systematic radiologic diagnosis and staging according to guidelines of the American Association for the Study of Liver Diseases. Radiographics. 33(6):1653-68, 2013
- Patel M et al: Hepatocellular carcinoma: diagnostics and screening. J Eval Clin Pract. 18(2):335-42, 2012
- Maturen KE et al: Posterior acoustic enhancement in hepatocellular carcinoma. J Ultrasound Med. 30(4):495-9, 2011
- Murakami T et al: Ultrasonography, computed tomography and magnetic resonance imaging of hepatocellular carcinoma: toward improved treatment decisions. Oncology. 81 Suppl 1:86-99, 2011
- Lencioni R: Surveillance and early diagnosis of hepatocellular carcinoma. Dig Liver Dis. 42 Suppl 3:S223-7, 2010
- Kamaya A et al: Hypervascular liver lesions. Semin Ultrasound CT MR. 30(5):387-407, 2009
- Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases
