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Pediatrics
Diagnosis
Gastrointestinal
Liver Abnormalities
Hepatocellular Carcinoma
Hepatocellular Carcinoma
Alexander J. Towbin, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Definitions

            • Hepatocellular carcinoma (HCC): Malignant tumor of hepatocytes
            • Hepatocyte-specific contrast agent (HSCA): MR contrast agent with substantial hepatic uptake & biliary excretion

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Ultrasonographic Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  Selected References

                                  1. Lau CS et al: Hepatocellular carcinoma in the pediatric population: a population based clinical outcomes study involving 257 patients from the surveillance, epidemiology, and end result (SEER) database (1973-2011). HPB Surg. 2015:670728, 2015
                                  2. Allan BJ et al: A review of 218 pediatric cases of hepatocellular carcinoma. J Pediatr Surg. 49(1):166-71; discussion 171, 2014
                                  3. McAteer JP et al: Hepatocellular carcinoma in children: epidemiology and the impact of regional lymphadenectomy on surgical outcomes. J Pediatr Surg. 48(11):2194-201, 2013
                                  4. Chung EM et al: From the archives of the AFIP: Pediatric liver masses: radiologic-pathologic correlation. Part 2. Malignant tumors. Radiographics. 31(2):483-507, 2011
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  KEY FACTS

                                  • Terminology

                                    • Imaging

                                      • Top Differential Diagnoses

                                        • Clinical Issues

                                          TERMINOLOGY

                                          • Definitions

                                            • Hepatocellular carcinoma (HCC): Malignant tumor of hepatocytes
                                            • Hepatocyte-specific contrast agent (HSCA): MR contrast agent with substantial hepatic uptake & biliary excretion

                                          IMAGING

                                          • General Features

                                            • CT Findings

                                              • MR Findings

                                                • Ultrasonographic Findings

                                                  • Imaging Recommendations

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        • Gross Pathologic & Surgical Features

                                                          CLINICAL ISSUES

                                                          • Presentation

                                                            • Demographics

                                                              • Natural History & Prognosis

                                                                • Treatment

                                                                  Selected References

                                                                  1. Lau CS et al: Hepatocellular carcinoma in the pediatric population: a population based clinical outcomes study involving 257 patients from the surveillance, epidemiology, and end result (SEER) database (1973-2011). HPB Surg. 2015:670728, 2015
                                                                  2. Allan BJ et al: A review of 218 pediatric cases of hepatocellular carcinoma. J Pediatr Surg. 49(1):166-71; discussion 171, 2014
                                                                  3. McAteer JP et al: Hepatocellular carcinoma in children: epidemiology and the impact of regional lymphadenectomy on surgical outcomes. J Pediatr Surg. 48(11):2194-201, 2013
                                                                  4. Chung EM et al: From the archives of the AFIP: Pediatric liver masses: radiologic-pathologic correlation. Part 2. Malignant tumors. Radiographics. 31(2):483-507, 2011