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Hepatocellular Carcinoma
Jeffrey Olpin, MD
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7

OVERVIEW

  • General Comments

    • Classification

      PATHOLOGY

      • Routes of Spread

        • General Features

          • Gross Pathology & Surgical Features

            • Microscopic Features

              IMAGING FINDINGS

              • Detection

                • Staging

                  CLINICAL ISSUES

                  • Presentation

                    • Cancer History

                      • Treatment Options

                        REPORTING CHECKLIST

                        • T Staging

                          • N Staging

                            • M Staging

                              Selected References

                              1. Amin MB et al: AJCC Cancer Staging Manual. 8th Ed. Springer New York, 2017
                              2. Dimitroulis D et al: From diagnosis to treatment of hepatocellular carcinoma: an epidemic problem for both developed and developing world. World J Gastroenterol. 23(29):5282-94, 2017
                              3. Fitzmorris P et al: Management of hepatocellular carcinoma. J Cancer Res Clin Oncol. 141(5):861-76, 2015
                              4. Lafaro KJ et al: Epidemiology of hepatocellular carcinoma. Surg Oncol Clin N Am. 24(1):1-17, 2015
                              5. Rosenkrantz AB et al: New OPTN/UNOS classification system for nodules in cirrhotic livers detected with MR imaging: effect on hepatocellular carcinoma detection and transplantation allocation. Radiology. 274(2):426-33, 2015
                              6. Choi JY et al: CT and MR imaging diagnosis and staging of hepatocellular carcinoma: part II. Extracellular agents, hepatobiliary agents, and ancillary imaging features. Radiology. 273(1):30-50, 2014
                              7. Choi JY et al: CT and MR imaging diagnosis and staging of hepatocellular carcinoma: part I. Development, growth, and spread: key pathologic and imaging aspects. Radiology. 272(3):635-54, 2014
                              8. Jha RC et al: LI-RADS categorization of benign and likely benign findings in patients at risk of hepatocellular carcinoma: a pictorial atlas. AJR Am J Roentgenol. 203(1):W48-69, 2014
                              9. Kirstein MM et al: The pathogenesis of hepatocellular carcinoma. Dig Dis. 32(5):545-53, 2014
                              10. Roth CG et al: Hepatocellular carcinoma and other hepatic malignancies: MR imaging. Radiol Clin North Am. 52(4):683-707, 2014
                              11. Seale MK et al: Hepatobiliary-specific MR contrast agents: role in imaging the liver and biliary tree. Radiographics. 29(6):1725-48, 2009
                              12. Hanna RF et al: Cirrhosis-associated hepatocellular nodules: correlation of histopathologic and MR imaging features. Radiographics. 28(3):747-69, 2008
                              13. Willatt JM et al: MR imaging of hepatocellular carcinoma in the cirrhotic liver: challenges and controversies. Radiology. 247(2):311-30, 2008
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              OVERVIEW

                              • General Comments

                                • Classification

                                  PATHOLOGY

                                  • Routes of Spread

                                    • General Features

                                      • Gross Pathology & Surgical Features

                                        • Microscopic Features

                                          IMAGING FINDINGS

                                          • Detection

                                            • Staging

                                              CLINICAL ISSUES

                                              • Presentation

                                                • Cancer History

                                                  • Treatment Options

                                                    REPORTING CHECKLIST

                                                    • T Staging

                                                      • N Staging

                                                        • M Staging

                                                          Selected References

                                                          1. Amin MB et al: AJCC Cancer Staging Manual. 8th Ed. Springer New York, 2017
                                                          2. Dimitroulis D et al: From diagnosis to treatment of hepatocellular carcinoma: an epidemic problem for both developed and developing world. World J Gastroenterol. 23(29):5282-94, 2017
                                                          3. Fitzmorris P et al: Management of hepatocellular carcinoma. J Cancer Res Clin Oncol. 141(5):861-76, 2015
                                                          4. Lafaro KJ et al: Epidemiology of hepatocellular carcinoma. Surg Oncol Clin N Am. 24(1):1-17, 2015
                                                          5. Rosenkrantz AB et al: New OPTN/UNOS classification system for nodules in cirrhotic livers detected with MR imaging: effect on hepatocellular carcinoma detection and transplantation allocation. Radiology. 274(2):426-33, 2015
                                                          6. Choi JY et al: CT and MR imaging diagnosis and staging of hepatocellular carcinoma: part II. Extracellular agents, hepatobiliary agents, and ancillary imaging features. Radiology. 273(1):30-50, 2014
                                                          7. Choi JY et al: CT and MR imaging diagnosis and staging of hepatocellular carcinoma: part I. Development, growth, and spread: key pathologic and imaging aspects. Radiology. 272(3):635-54, 2014
                                                          8. Jha RC et al: LI-RADS categorization of benign and likely benign findings in patients at risk of hepatocellular carcinoma: a pictorial atlas. AJR Am J Roentgenol. 203(1):W48-69, 2014
                                                          9. Kirstein MM et al: The pathogenesis of hepatocellular carcinoma. Dig Dis. 32(5):545-53, 2014
                                                          10. Roth CG et al: Hepatocellular carcinoma and other hepatic malignancies: MR imaging. Radiol Clin North Am. 52(4):683-707, 2014
                                                          11. Seale MK et al: Hepatobiliary-specific MR contrast agents: role in imaging the liver and biliary tree. Radiographics. 29(6):1725-48, 2009
                                                          12. Hanna RF et al: Cirrhosis-associated hepatocellular nodules: correlation of histopathologic and MR imaging features. Radiographics. 28(3):747-69, 2008
                                                          13. Willatt JM et al: MR imaging of hepatocellular carcinoma in the cirrhotic liver: challenges and controversies. Radiology. 247(2):311-30, 2008