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Hepatoma Tumor Thrombus
Frank Chen, MD; Corinne Deurdulian, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Tumor-in-vein
            • Definitions

              • Invasion of portal vein by hepatocellular carcinoma (HCC)

            IMAGING

            • General Features

              • Ultrasonographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          • Reporting Tips

                                            Selected References

                                            1. Quencer KB et al: Tumor thrombus: incidence, imaging, prognosis and treatment. Cardiovasc Diagn Ther. 7(Suppl 3):S165-S177, 2017
                                            2. Sereni CP et al: Portal vein thrombus and infiltrative HCC: a pictoral review. Abdom Radiol (NY). 42(1):159-170, 2017
                                            3. Canellas R et al: Characterization of portal vein thrombosis (neoplastic versus bland) on CT images using software-based texture analysis and thrombus density (Hounsfield units). AJR Am J Roentgenol. 207(5):W81-W87, 2016
                                            4. Zhu K et al: Hepatocellular carcinoma with portal vein tumor thrombus: treatment with transarterial chemoembolization combined with sorafenib--a retrospective controlled study. Radiology. 272(1):284-93, 2014
                                            5. Catalano OA et al: Differentiation of malignant thrombus from bland thrombus of the portal vein in patients with hepatocellular carcinoma: application of diffusion-weighted MR imaging. Radiology. 254(1):154-62, 2010
                                            6. Tarantino L et al: Diagnosis of benign and malignant portal vein thrombosis in cirrhotic patients with hepatocellular carcinoma: color Doppler US, contrast-enhanced US, and fine-needle biopsy. Abdom Imaging. 31(5):537-44, 2006
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Synonyms

                                                        • Tumor-in-vein
                                                      • Definitions

                                                        • Invasion of portal vein by hepatocellular carcinoma (HCC)

                                                      IMAGING

                                                      • General Features

                                                        • Ultrasonographic Findings

                                                          • CT Findings

                                                            • MR Findings

                                                              • Nuclear Medicine Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Staging, Grading, & Classification

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  • Image Interpretation Pearls

                                                                                    • Reporting Tips

                                                                                      Selected References

                                                                                      1. Quencer KB et al: Tumor thrombus: incidence, imaging, prognosis and treatment. Cardiovasc Diagn Ther. 7(Suppl 3):S165-S177, 2017
                                                                                      2. Sereni CP et al: Portal vein thrombus and infiltrative HCC: a pictoral review. Abdom Radiol (NY). 42(1):159-170, 2017
                                                                                      3. Canellas R et al: Characterization of portal vein thrombosis (neoplastic versus bland) on CT images using software-based texture analysis and thrombus density (Hounsfield units). AJR Am J Roentgenol. 207(5):W81-W87, 2016
                                                                                      4. Zhu K et al: Hepatocellular carcinoma with portal vein tumor thrombus: treatment with transarterial chemoembolization combined with sorafenib--a retrospective controlled study. Radiology. 272(1):284-93, 2014
                                                                                      5. Catalano OA et al: Differentiation of malignant thrombus from bland thrombus of the portal vein in patients with hepatocellular carcinoma: application of diffusion-weighted MR imaging. Radiology. 254(1):154-62, 2010
                                                                                      6. Tarantino L et al: Diagnosis of benign and malignant portal vein thrombosis in cirrhotic patients with hepatocellular carcinoma: color Doppler US, contrast-enhanced US, and fine-needle biopsy. Abdom Imaging. 31(5):537-44, 2006