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Heterotopic Pregnancy
Paula J. Woodward, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Definitions

              • 2 concurrent pregnancies, at least 1 of which is ectopic in location

            IMAGING

            • General Features

              • Imaging Recommendations

                DIFFERENTIAL DIAGNOSIS

                  PATHOLOGY

                  • General Features

                    CLINICAL ISSUES

                    • Presentation

                      • Demographics

                        • Natural History & Prognosis

                          • Treatment

                            DIAGNOSTIC CHECKLIST

                            • Image Interpretation Pearls

                              Selected References

                              1. Lv S et al: Management strategies of heterotopic pregnancy following in vitro fertilization-embryo transfer. Taiwan J Obstet Gynecol. 59(1):67-72, 2020
                              2. Nabi U et al: Heterotopic pregnancy - a diagnostic challenge. Six Case Reports and Literature Review. Cureus. 11(11):e6080, 2019
                              3. Wu Z et al: Clinical analysis of 50 patients with heterotopic pregnancy after ovulation induction or embryo transfer. Eur J Med Res. 23(1):17, 2018
                              4. Guan Y et al: Clinical outcomes of patients with heterotopic pregnancy after surgical treatment. J Minim Invasive Gynecol. 24(7):1111-5, 2017
                              5. Dibble EH et al: Imaging unusual pregnancy implantations: rare ectopic pregnancies and more. AJR Am J Roentgenol. 207(6):1380-92, 2016
                              6. Goettler S et al: Heterotopic pregnancy. N Engl J Med. 375(20):1982, 2016
                              7. Avitabile NC et al: Two cases of heterotopic pregnancy: review of the literature and sonographic diagnosis in the emergency department. J Ultrasound Med. 34(3):527-30, 2015
                              8. Perkins KM et al: Risk of ectopic pregnancy associated with assisted reproductive technology in the United States, 2001-2011. Obstet Gynecol. 125(1):70-8, 2015
                              9. OuYang Z et al: Heterotopic cesarean scar pregnancy: diagnosis, treatment, and prognosis. J Ultrasound Med. 33(9):1533-7, 2014
                              10. Savelli L et al: Heterotopic interstitial pregnancy successfully treated with ultrasound-guided potassium chloride injection in the ectopic embryo. J Obstet Gynaecol. 34(3):276-7, 2014
                              11. Talbot K et al: Heterotopic pregnancy. J Obstet Gynaecol. 31(1):7-12, 2011
                              12. Lavanya R et al: Successful pregnancy following medical management of heterotopic pregnancy. J Hum Reprod Sci. 2(1):35-40, 2009
                              13. Luo X et al: Heterotopic pregnancy following in vitro fertilization and embryo transfer: 12 cases report. Arch Gynecol Obstet. 280(2):325-9, 2009
                              14. Clayton HB et al: A comparison of heterotopic and intrauterine-only pregnancy outcomes after assisted reproductive technologies in the United States from 1999 to 2002. Fertil Steril. 87(2):303-9, 2007
                              15. Rabbani I et al: Heterotopic pregnancy is not rare. A case report and literature review. J Obstet Gynaecol. 25(2):204-5, 2005
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              KEY FACTS

                              • Terminology

                                • Imaging

                                  • Top Differential Diagnoses

                                    • Clinical Issues

                                      • Diagnostic Checklist

                                        TERMINOLOGY

                                        • Definitions

                                          • 2 concurrent pregnancies, at least 1 of which is ectopic in location

                                        IMAGING

                                        • General Features

                                          • Imaging Recommendations

                                            DIFFERENTIAL DIAGNOSIS

                                              PATHOLOGY

                                              • General Features

                                                CLINICAL ISSUES

                                                • Presentation

                                                  • Demographics

                                                    • Natural History & Prognosis

                                                      • Treatment

                                                        DIAGNOSTIC CHECKLIST

                                                        • Image Interpretation Pearls

                                                          Selected References

                                                          1. Lv S et al: Management strategies of heterotopic pregnancy following in vitro fertilization-embryo transfer. Taiwan J Obstet Gynecol. 59(1):67-72, 2020
                                                          2. Nabi U et al: Heterotopic pregnancy - a diagnostic challenge. Six Case Reports and Literature Review. Cureus. 11(11):e6080, 2019
                                                          3. Wu Z et al: Clinical analysis of 50 patients with heterotopic pregnancy after ovulation induction or embryo transfer. Eur J Med Res. 23(1):17, 2018
                                                          4. Guan Y et al: Clinical outcomes of patients with heterotopic pregnancy after surgical treatment. J Minim Invasive Gynecol. 24(7):1111-5, 2017
                                                          5. Dibble EH et al: Imaging unusual pregnancy implantations: rare ectopic pregnancies and more. AJR Am J Roentgenol. 207(6):1380-92, 2016
                                                          6. Goettler S et al: Heterotopic pregnancy. N Engl J Med. 375(20):1982, 2016
                                                          7. Avitabile NC et al: Two cases of heterotopic pregnancy: review of the literature and sonographic diagnosis in the emergency department. J Ultrasound Med. 34(3):527-30, 2015
                                                          8. Perkins KM et al: Risk of ectopic pregnancy associated with assisted reproductive technology in the United States, 2001-2011. Obstet Gynecol. 125(1):70-8, 2015
                                                          9. OuYang Z et al: Heterotopic cesarean scar pregnancy: diagnosis, treatment, and prognosis. J Ultrasound Med. 33(9):1533-7, 2014
                                                          10. Savelli L et al: Heterotopic interstitial pregnancy successfully treated with ultrasound-guided potassium chloride injection in the ectopic embryo. J Obstet Gynaecol. 34(3):276-7, 2014
                                                          11. Talbot K et al: Heterotopic pregnancy. J Obstet Gynaecol. 31(1):7-12, 2011
                                                          12. Lavanya R et al: Successful pregnancy following medical management of heterotopic pregnancy. J Hum Reprod Sci. 2(1):35-40, 2009
                                                          13. Luo X et al: Heterotopic pregnancy following in vitro fertilization and embryo transfer: 12 cases report. Arch Gynecol Obstet. 280(2):325-9, 2009
                                                          14. Clayton HB et al: A comparison of heterotopic and intrauterine-only pregnancy outcomes after assisted reproductive technologies in the United States from 1999 to 2002. Fertil Steril. 87(2):303-9, 2007
                                                          15. Rabbani I et al: Heterotopic pregnancy is not rare. A case report and literature review. J Obstet Gynaecol. 25(2):204-5, 2005