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High-Density Mass
Ethan O. Cohen, MD; Rosalind Candelaria, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Diagnostic Checklist

            TERMINOLOGY

            • Definitions

              • Mass on mammography/DBT visually denser than similar volume of fibroglandular tissue

            IMAGING

            • General Features

              • Mammographic Findings

                • Imaging Recommendations

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      CLINICAL ISSUES

                      • Presentation

                        DIAGNOSTIC CHECKLIST

                        • Image Interpretation Pearls

                          Selected References

                          1. Stelmach A et al: Typical medullary breast carcinoma: Clinical outcomes and treatment results. Breast J. ePub, 2017
                          2. Boyan W et al: Tubular carcinoma of the breast: a single institution's experience of a favorable prognosis. Am Surg. 82(6):505-9, 2016
                          3. Sippo DA et al: Metastatic disease to the breast from extramammary malignancies: a multimodality pictorial review. Curr Probl Diagn Radiol. 45(3):225-32, 2016
                          4. Zhang Y et al: Phyllodes tumor of the breast: histopathologic features, differential diagnosis, and molecular/genetic updates. Arch Pathol Lab Med. 140(7):665-71, 2016
                          5. Plaza MJ et al: Phyllodes tumor: review of key imaging characteristics. Breast Dis. 35(2):79-86, 2015
                          6. Ssi-Yan-Kai G et al: Granular cell breast cancer: a rare misleading lesion. Diagn Interv Imaging. 96(3):287-9, 2015
                          7. Larribe M et al: Breast cancers with round lumps: correlations between imaging and anatomopathology. Diagn Interv Imaging. 95(1):37-46, 2014
                          8. Abbas J et al: Intramammary metastases: comparison of mammographic and ultrasound features. Eur J Radiol. 82(9):1423-30, 2013
                          9. DeLair DF et al: Non-mammary metastases to the breast and axilla: a study of 85 cases. Mod Pathol. 26(3):343-9, 2013
                          10. Lee SK et al: The clinical meaning of intramammary lymph nodes. Oncology. 84(1):1-5, 2013
                          11. Yang M et al: Pure mucinous breast carcinoma: a favorable subtype. Breast Care (Basel). 8(1):56-9, 2013
                          12. Abdullgaffar B et al: The significance of intramammary lymph nodes in breast cancer: a systematic review and meta-analysis. Int J Surg Pathol. 20(6):555-63, 2012
                          13. Jeong SJ et al: Medullary carcinoma of the breast: MRI findings. AJR Am J Roentgenol. 198(5):W482-7, 2012
                          14. Surov A et al. Primary and secondary breast lymphoma: prevalence, clinical signs and radiological features. Br J Radiol. 2012 Jun;85(1014):e195-205.
                          15. Tan H et al: Imaging findings in phyllodes tumors of the breast. Eur J Radiol. 81(1):e62-9, 2012
                          16. Lee JH et al: Metastases to the breast from extramammary malignancies−sonographic features. J Clin Ultrasound. 39(5):248-55, 2011
                          17. Trop I et al: Breast abscesses: evidence-based algorithms for diagnosis, management, and follow-up. Radiographics. 31(6):1683-99, 2011
                          18. Woods RW et al: The mammographic density of a mass is a significant predictor of breast cancer. Radiology. 258(2):417-25, 2011
                          19. Monzawa S et al: Mucinous carcinoma of the breast: MRI features of pure and mixed forms with histopathologic correlation. AJR Am J Roentgenol. 192(3):W125-31, 2009
                          20. Grabowski J et al: Intracystic papillary carcinoma: a review of 917 cases. Cancer. 113(5):916-20, 2008
                          21. Harvey JA: Unusual breast cancers: useful clues to expanding the differential diagnosis. Radiology. 242(3):683-94, 2007
                          22. Yang WT et al: Sonographic and mammographic appearances of granular cell tumors of the breast with pathological correlation. J Clin Ultrasound. 34(4):153-60, 2006
                          23. Franceschini G et al: Phyllodes tumor of the breast: magnetic resonance imaging findings and surgical treatment. Breast J. 11(2):144-5, 2005
                          24. Dogan BE et al: Intracystic papillary carcinoma of the breast. AJR Am J Roentgenol. 181(1):186, 2003
                          25. Sheppard DG et al: Tubular carcinoma of the breast: mammographic and sonographic features. AJR Am J Roentgenol. 174(1):253-7, 2000
                          26. Yang WT et al: Nonmammary malignancies of the breast: ultrasound, CT, and MRI. Semin Ultrasound CT MR. 21(5):375-94, 2000
                          27. Cory RC et al: The mammographic density of breast cancer. AJR Am J Roentgenol. 160(2):418-9, 1993
                          28. Jackson VP et al: Diagnostic importance of the radiographic density of noncalcified breast masses: analysis of 91 lesions. AJR Am J Roentgenol. 157(1):25-8, 1991
                          29. Meyer JE et al: Medullary carcinoma of the breast: mammographic and US appearance. Radiology. 170(1 Pt 1):79-82, 1989
                          Related Anatomy
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                          Related Differential Diagnoses
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                          References
                          Tables

                          Tables

                          KEY FACTS

                          • Terminology

                            • Imaging

                              • Top Differential Diagnoses

                                • Pathology

                                  • Diagnostic Checklist

                                    TERMINOLOGY

                                    • Definitions

                                      • Mass on mammography/DBT visually denser than similar volume of fibroglandular tissue

                                    IMAGING

                                    • General Features

                                      • Mammographic Findings

                                        • Imaging Recommendations

                                          DIFFERENTIAL DIAGNOSIS

                                            PATHOLOGY

                                            • General Features

                                              CLINICAL ISSUES

                                              • Presentation

                                                DIAGNOSTIC CHECKLIST

                                                • Image Interpretation Pearls

                                                  Selected References

                                                  1. Stelmach A et al: Typical medullary breast carcinoma: Clinical outcomes and treatment results. Breast J. ePub, 2017
                                                  2. Boyan W et al: Tubular carcinoma of the breast: a single institution's experience of a favorable prognosis. Am Surg. 82(6):505-9, 2016
                                                  3. Sippo DA et al: Metastatic disease to the breast from extramammary malignancies: a multimodality pictorial review. Curr Probl Diagn Radiol. 45(3):225-32, 2016
                                                  4. Zhang Y et al: Phyllodes tumor of the breast: histopathologic features, differential diagnosis, and molecular/genetic updates. Arch Pathol Lab Med. 140(7):665-71, 2016
                                                  5. Plaza MJ et al: Phyllodes tumor: review of key imaging characteristics. Breast Dis. 35(2):79-86, 2015
                                                  6. Ssi-Yan-Kai G et al: Granular cell breast cancer: a rare misleading lesion. Diagn Interv Imaging. 96(3):287-9, 2015
                                                  7. Larribe M et al: Breast cancers with round lumps: correlations between imaging and anatomopathology. Diagn Interv Imaging. 95(1):37-46, 2014
                                                  8. Abbas J et al: Intramammary metastases: comparison of mammographic and ultrasound features. Eur J Radiol. 82(9):1423-30, 2013
                                                  9. DeLair DF et al: Non-mammary metastases to the breast and axilla: a study of 85 cases. Mod Pathol. 26(3):343-9, 2013
                                                  10. Lee SK et al: The clinical meaning of intramammary lymph nodes. Oncology. 84(1):1-5, 2013
                                                  11. Yang M et al: Pure mucinous breast carcinoma: a favorable subtype. Breast Care (Basel). 8(1):56-9, 2013
                                                  12. Abdullgaffar B et al: The significance of intramammary lymph nodes in breast cancer: a systematic review and meta-analysis. Int J Surg Pathol. 20(6):555-63, 2012
                                                  13. Jeong SJ et al: Medullary carcinoma of the breast: MRI findings. AJR Am J Roentgenol. 198(5):W482-7, 2012
                                                  14. Surov A et al. Primary and secondary breast lymphoma: prevalence, clinical signs and radiological features. Br J Radiol. 2012 Jun;85(1014):e195-205.
                                                  15. Tan H et al: Imaging findings in phyllodes tumors of the breast. Eur J Radiol. 81(1):e62-9, 2012
                                                  16. Lee JH et al: Metastases to the breast from extramammary malignancies−sonographic features. J Clin Ultrasound. 39(5):248-55, 2011
                                                  17. Trop I et al: Breast abscesses: evidence-based algorithms for diagnosis, management, and follow-up. Radiographics. 31(6):1683-99, 2011
                                                  18. Woods RW et al: The mammographic density of a mass is a significant predictor of breast cancer. Radiology. 258(2):417-25, 2011
                                                  19. Monzawa S et al: Mucinous carcinoma of the breast: MRI features of pure and mixed forms with histopathologic correlation. AJR Am J Roentgenol. 192(3):W125-31, 2009
                                                  20. Grabowski J et al: Intracystic papillary carcinoma: a review of 917 cases. Cancer. 113(5):916-20, 2008
                                                  21. Harvey JA: Unusual breast cancers: useful clues to expanding the differential diagnosis. Radiology. 242(3):683-94, 2007
                                                  22. Yang WT et al: Sonographic and mammographic appearances of granular cell tumors of the breast with pathological correlation. J Clin Ultrasound. 34(4):153-60, 2006
                                                  23. Franceschini G et al: Phyllodes tumor of the breast: magnetic resonance imaging findings and surgical treatment. Breast J. 11(2):144-5, 2005
                                                  24. Dogan BE et al: Intracystic papillary carcinoma of the breast. AJR Am J Roentgenol. 181(1):186, 2003
                                                  25. Sheppard DG et al: Tubular carcinoma of the breast: mammographic and sonographic features. AJR Am J Roentgenol. 174(1):253-7, 2000
                                                  26. Yang WT et al: Nonmammary malignancies of the breast: ultrasound, CT, and MRI. Semin Ultrasound CT MR. 21(5):375-94, 2000
                                                  27. Cory RC et al: The mammographic density of breast cancer. AJR Am J Roentgenol. 160(2):418-9, 1993
                                                  28. Jackson VP et al: Diagnostic importance of the radiographic density of noncalcified breast masses: analysis of 91 lesions. AJR Am J Roentgenol. 157(1):25-8, 1991
                                                  29. Meyer JE et al: Medullary carcinoma of the breast: mammographic and US appearance. Radiology. 170(1 Pt 1):79-82, 1989