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High-Grade Surface Osteosarcoma
Behrang Amini, MD, PhD; B. J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Definitions

              • High-grade, malignant, bone-forming neoplasm arising on surface of bone

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        Selected References

                                        1. Deng Z et al: High-grade surface osteosarcoma: clinical features and oncologic outcome. J Bone Oncol. 23:100288, 2020
                                        2. Yarmish G et al: Imaging characteristics of primary osteosarcoma: nonconventional subtypes. Radiographics. 30(6):1653-72, 2010
                                        3. Staals EL et al: High-grade surface osteosarcoma: a review of 25 cases from the Rizzoli Institute. Cancer. 112(7):1592-9, 2008
                                        4. Klein MJ et al. High-grade surface osteosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours: Tumours of Soft Tissue and Bone. IARC Press. 417-8, 2020
                                        5. Vanel D et al: Radiological study of 12 high-grade surface osteosarcomas. Skeletal Radiol. 30(12):667-71, 2001
                                        6. Murphey MD et al: The many faces of osteosarcoma. Radiographics. 17(5):1205-31, 1997
                                        7. Wold LE et al: High-grade surface osteosarcomas. Am J Surg Pathol. 8(3):181-6, 1984
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Definitions

                                                    • High-grade, malignant, bone-forming neoplasm arising on surface of bone

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • Staging, Grading, & Classification

                                                                • Gross Pathologic & Surgical Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              Selected References

                                                                              1. Deng Z et al: High-grade surface osteosarcoma: clinical features and oncologic outcome. J Bone Oncol. 23:100288, 2020
                                                                              2. Yarmish G et al: Imaging characteristics of primary osteosarcoma: nonconventional subtypes. Radiographics. 30(6):1653-72, 2010
                                                                              3. Staals EL et al: High-grade surface osteosarcoma: a review of 25 cases from the Rizzoli Institute. Cancer. 112(7):1592-9, 2008
                                                                              4. Klein MJ et al. High-grade surface osteosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours: Tumours of Soft Tissue and Bone. IARC Press. 417-8, 2020
                                                                              5. Vanel D et al: Radiological study of 12 high-grade surface osteosarcomas. Skeletal Radiol. 30(12):667-71, 2001
                                                                              6. Murphey MD et al: The many faces of osteosarcoma. Radiographics. 17(5):1205-31, 1997
                                                                              7. Wold LE et al: High-grade surface osteosarcomas. Am J Surg Pathol. 8(3):181-6, 1984