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Histiocytic Diseases
Bryan R. Foster, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Erdheim-Chester disease (ECD)
              • Rosai-Dorfman disease (RDD)
            • Synonyms

              • RDD: Sinus histiocytosis with massive lymphadenopathy
            • Definitions

              • Group of neoplastic disorders resulting in excessive infiltration of histiocytes (macrophages or dendritic cells) into tissue

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      Selected References

                                      1. Chung AD et al: Primary and secondary diseases of the perinephric space: an approach to imaging diagnosis with emphasis on MRI. Clin Radiol. 76(1):75.e13-75.e26, 2021
                                      2. Huynh KN et al: Histiocytosis and neoplasms of macrophage-dendritic cell lineages: multimodality imaging with emphasis on PET/CT. Radiographics. 41(2):576-94, 2021
                                      3. Park H et al: Imaging of histiocytosis in the era of genomic medicine. Radiographics. 39(1):95-114, 2019
                                      4. Wang F et al: Multisystemic imaging findings in Chinese patients with Erdheim-Chester disease. AJR Am J Roentgenol. 213(6):1179-86, 2019
                                      5. Gumeler E et al: Computed tomography and magnetic resonance imaging of peripelvic and periureteric pathologies. Abdom Radiol (NY). 43(9):2400-11, 2018
                                      6. Nikpanah M et al: Abdominal involvement in Erdheim-Chester disease (ECD): MRI and CT imaging findings and their association with BRAFV600E mutation. Eur Radiol. 28(9):3751-9, 2018
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Pathology

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Erdheim-Chester disease (ECD)
                                                  • Rosai-Dorfman disease (RDD)
                                                • Synonyms

                                                  • RDD: Sinus histiocytosis with massive lymphadenopathy
                                                • Definitions

                                                  • Group of neoplastic disorders resulting in excessive infiltration of histiocytes (macrophages or dendritic cells) into tissue

                                                IMAGING

                                                • General Features

                                                  • Radiographic Findings

                                                    • CT Findings

                                                      • MR Findings

                                                        • Nuclear Medicine Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          Selected References

                                                                          1. Chung AD et al: Primary and secondary diseases of the perinephric space: an approach to imaging diagnosis with emphasis on MRI. Clin Radiol. 76(1):75.e13-75.e26, 2021
                                                                          2. Huynh KN et al: Histiocytosis and neoplasms of macrophage-dendritic cell lineages: multimodality imaging with emphasis on PET/CT. Radiographics. 41(2):576-94, 2021
                                                                          3. Park H et al: Imaging of histiocytosis in the era of genomic medicine. Radiographics. 39(1):95-114, 2019
                                                                          4. Wang F et al: Multisystemic imaging findings in Chinese patients with Erdheim-Chester disease. AJR Am J Roentgenol. 213(6):1179-86, 2019
                                                                          5. Gumeler E et al: Computed tomography and magnetic resonance imaging of peripelvic and periureteric pathologies. Abdom Radiol (NY). 43(9):2400-11, 2018
                                                                          6. Nikpanah M et al: Abdominal involvement in Erdheim-Chester disease (ECD): MRI and CT imaging findings and their association with BRAFV600E mutation. Eur Radiol. 28(9):3751-9, 2018