link
Bookmarks
Hydroxyapatite Deposition Disease
B.J. Manaster, MD, PhD, FACR
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
0
20
5
1

KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        • Diagnostic Checklist

          TERMINOLOGY

          • Abbreviations

            • Hydroxyapatite deposition disease (HADD)
          • Synonyms

            • Milwaukee shoulder, calcific tendinitis, calcific bursitis
          • Definitions

            • Broad spectrum of musculoskeletal pathology due to hydroxyapatite crystal deposition
              • Primary HADD includes calcific tendonitis and bursitis
              • Secondary hydroxyapatite related to underlying disease; not further discussed in this section
                • End-stage renal disease
                • Collagen vascular disease
                • Vitamin D intoxication
                • Tumoral calcinosis

          IMAGING

          • General Features

            • Imaging Recommendations

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Greis AC et al: Evaluation and Nonsurgical Management of Rotator Cuff Calcific Tendinopathy. Orthop Clin North Am. 46(2):293-302, 2015
                                          2. Lanza E et al: Ultrasound-guided percutaneous irrigation in rotator cuff calcific tendinopathy: what is the evidence? A systematic review with proposals for future reporting. Eur Radiol. ePub, 2015
                                          3. Del Castillo-González F et al: Treatment of the calcific tendinopathy of the rotator cuff by ultrasound-guided percutaneous needle lavage. Two years prospective study. Muscles Ligaments Tendons J. 4(4):407-12, 2014
                                          4. Gabra N et al: Retropharyngeal calcific tendinitis mimicking a retropharyngeal phlegmon. Case Rep Otolaryngol. 2013:912628, 2013
                                          5. Torbati SS et al: Acute calcific tendinitis of the wrist. J Emerg Med. 44(2):352-4, 2013
                                          6. Ogon P et al: Prognostic factors in nonoperative therapy for chronic symptomatic calcific tendinitis of the shoulder. Arthritis Rheum. 60(10):2978-84, 2009
                                          7. Serafini G et al: Rotator cuff calcific tendonitis: short-term and 10-year outcomes after two-needle us-guided percutaneous treatment--nonrandomized controlled trial. Radiology. 252(1):157-64, 2009
                                          8. Farid N et al: Miscellaneous conditions of the shoulder: anatomical, clinical, and pictorial review emphasizing potential pitfalls in imaging diagnosis. Eur J Radiol. 68(1):88-105, 2008
                                          9. Fodor D et al: Crystal-associated synovitis- ultrasonographic feature and clinical correlation. Ortop Traumatol Rehabil. 10(2):99-110, 2008
                                          10. Carlson AP et al: Disorders of tumoral calcification of the spine: illustrative case study and review of the literature. J Spinal Disord Tech. 20(1):97-103, 2007
                                          11. Choi MH et al: Imaging features of crystal-induced arthropathy. Rheum Dis Clin North Am. 32(2):427-46, viii, 2006
                                          12. Devauchelle-Pensec V et al: Performance of hand radiographs in predicting the diagnosis in patients with early arthritis. J Rheumatol. 33(8):1511-5, 2006
                                          13. Duey RE et al: Carpal tunnel syndrome resulting from hydroxyapatite deposition. Curr Probl Diagn Radiol. 35(6):261-3, 2006
                                          14. Feydy A et al: Cervical spine and crystal-associated diseases: imaging findings. Eur Radiol. 16(2):459-68, 2006
                                          15. Bui-Mansfield LT et al: Magnetic resonance appearance of bone marrow edema associated with hydroxyapatite deposition disease without cortical erosion. J Comput Assist Tomogr. 29(1):103-7, 2005
                                          16. Kuroda H et al: A case of probable hydroxyapatite deposition disease (HADD) of the hip. Magn Reson Med Sci. 3(3):141-4, 2004
                                          17. Garcia GM et al: Hydroxyapatite crystal deposition disease. Semin Musculoskelet Radiol. 7(3):187-93, 2003
                                          18. Molloy ES et al: Hydroxyapatite deposition disease of the joint. Curr Rheumatol Rep. 5(3):215-21, 2003
                                          19. Pay S et al: Calcium pyrophosphate dihydrate and hydroxyapatite crystal deposition in the joint: new developments relevant to the clinician. Curr Rheumatol Rep. 5(3):235-43, 2003
                                          20. Hayes CW et al: Calcium hydroxyapatite deposition disease. Radiographics. 10(6):1031-48, 1990
                                          Related Anatomy
                                          Loading...
                                          Related Differential Diagnoses
                                          Loading...
                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Hydroxyapatite deposition disease (HADD)
                                                  • Synonyms

                                                    • Milwaukee shoulder, calcific tendinitis, calcific bursitis
                                                  • Definitions

                                                    • Broad spectrum of musculoskeletal pathology due to hydroxyapatite crystal deposition
                                                      • Primary HADD includes calcific tendonitis and bursitis
                                                      • Secondary hydroxyapatite related to underlying disease; not further discussed in this section
                                                        • End-stage renal disease
                                                        • Collagen vascular disease
                                                        • Vitamin D intoxication
                                                        • Tumoral calcinosis

                                                  IMAGING

                                                  • General Features

                                                    • Imaging Recommendations

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • MR Findings

                                                            • Ultrasonographic Findings

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Greis AC et al: Evaluation and Nonsurgical Management of Rotator Cuff Calcific Tendinopathy. Orthop Clin North Am. 46(2):293-302, 2015
                                                                                  2. Lanza E et al: Ultrasound-guided percutaneous irrigation in rotator cuff calcific tendinopathy: what is the evidence? A systematic review with proposals for future reporting. Eur Radiol. ePub, 2015
                                                                                  3. Del Castillo-González F et al: Treatment of the calcific tendinopathy of the rotator cuff by ultrasound-guided percutaneous needle lavage. Two years prospective study. Muscles Ligaments Tendons J. 4(4):407-12, 2014
                                                                                  4. Gabra N et al: Retropharyngeal calcific tendinitis mimicking a retropharyngeal phlegmon. Case Rep Otolaryngol. 2013:912628, 2013
                                                                                  5. Torbati SS et al: Acute calcific tendinitis of the wrist. J Emerg Med. 44(2):352-4, 2013
                                                                                  6. Ogon P et al: Prognostic factors in nonoperative therapy for chronic symptomatic calcific tendinitis of the shoulder. Arthritis Rheum. 60(10):2978-84, 2009
                                                                                  7. Serafini G et al: Rotator cuff calcific tendonitis: short-term and 10-year outcomes after two-needle us-guided percutaneous treatment--nonrandomized controlled trial. Radiology. 252(1):157-64, 2009
                                                                                  8. Farid N et al: Miscellaneous conditions of the shoulder: anatomical, clinical, and pictorial review emphasizing potential pitfalls in imaging diagnosis. Eur J Radiol. 68(1):88-105, 2008
                                                                                  9. Fodor D et al: Crystal-associated synovitis- ultrasonographic feature and clinical correlation. Ortop Traumatol Rehabil. 10(2):99-110, 2008
                                                                                  10. Carlson AP et al: Disorders of tumoral calcification of the spine: illustrative case study and review of the literature. J Spinal Disord Tech. 20(1):97-103, 2007
                                                                                  11. Choi MH et al: Imaging features of crystal-induced arthropathy. Rheum Dis Clin North Am. 32(2):427-46, viii, 2006
                                                                                  12. Devauchelle-Pensec V et al: Performance of hand radiographs in predicting the diagnosis in patients with early arthritis. J Rheumatol. 33(8):1511-5, 2006
                                                                                  13. Duey RE et al: Carpal tunnel syndrome resulting from hydroxyapatite deposition. Curr Probl Diagn Radiol. 35(6):261-3, 2006
                                                                                  14. Feydy A et al: Cervical spine and crystal-associated diseases: imaging findings. Eur Radiol. 16(2):459-68, 2006
                                                                                  15. Bui-Mansfield LT et al: Magnetic resonance appearance of bone marrow edema associated with hydroxyapatite deposition disease without cortical erosion. J Comput Assist Tomogr. 29(1):103-7, 2005
                                                                                  16. Kuroda H et al: A case of probable hydroxyapatite deposition disease (HADD) of the hip. Magn Reson Med Sci. 3(3):141-4, 2004
                                                                                  17. Garcia GM et al: Hydroxyapatite crystal deposition disease. Semin Musculoskelet Radiol. 7(3):187-93, 2003
                                                                                  18. Molloy ES et al: Hydroxyapatite deposition disease of the joint. Curr Rheumatol Rep. 5(3):215-21, 2003
                                                                                  19. Pay S et al: Calcium pyrophosphate dihydrate and hydroxyapatite crystal deposition in the joint: new developments relevant to the clinician. Curr Rheumatol Rep. 5(3):235-43, 2003
                                                                                  20. Hayes CW et al: Calcium hydroxyapatite deposition disease. Radiographics. 10(6):1031-48, 1990