link
Bookmarks
Hypereosinophilic Pneumonia
Jeffrey P. Kanne, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
0
3
3
0

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Hypereosinophilic syndrome (HES)
            • Synonyms

              • Hypereosinophilia, acquired hypereosinophilia
            • Definitions

              • Rare idiopathic disorder characterized by overproduction of eosinophils with subsequent infiltration of & damage to multiple organs
                • Diagnostic criteria
                  • Sustained absolute eosinophil count ≥ 1,500 cells/mL for at least 6 months
                  • Evidence of end-organ damage
                  • Exclusion of other causes of eosinophilia
              • Heart & CNS most commonly involved
              • Lungs involved in approximately 40% of patients

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • Gross Pathologic & Surgical Features

                        • Microscopic Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  Selected References

                                  1. Simon D et al: Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract. J Allergy Clin Immunol. 126(1):3-13; quiz 14-5, 2010
                                  2. Simon HU et al: Refining the definition of hypereosinophilic syndrome. J Allergy Clin Immunol. 126(1):45-9, 2010
                                  3. Peros-Golubicić T et al: Hypereosinophilic syndrome: diagnosis and treatment. Curr Opin Pulm Med. 13(5):422-7, 2007
                                  4. Kang EY et al: Pulmonary involvement of idiopathic hypereosinophilic syndrome: CT findings in five patients. J Comput Assist Tomogr. 21(4):612-5, 1997
                                  5. Slabbynck H et al: Idiopathic hypereosinophilic syndrome-related pulmonary involvement diagnosed by bronchoalveolar lavage. Chest. 101(4):1178-80, 1992
                                  6. Spry CJ et al: Clinical features of fifteen patients with the hypereosinophilic syndrome. Q J Med. 52(205):1-22, 1983
                                  7. Epstein DM et al: The hypereosinophilic syndrome. Radiology. 140(1):59-62, 1981
                                  Related Anatomy
                                  Loading...
                                  Related Differential Diagnoses
                                  Loading...
                                  References
                                  Tables

                                  Tables

                                  KEY FACTS

                                  • Terminology

                                    • Imaging

                                      • Top Differential Diagnoses

                                        • Pathology

                                          • Clinical Issues

                                            TERMINOLOGY

                                            • Abbreviations

                                              • Hypereosinophilic syndrome (HES)
                                            • Synonyms

                                              • Hypereosinophilia, acquired hypereosinophilia
                                            • Definitions

                                              • Rare idiopathic disorder characterized by overproduction of eosinophils with subsequent infiltration of & damage to multiple organs
                                                • Diagnostic criteria
                                                  • Sustained absolute eosinophil count ≥ 1,500 cells/mL for at least 6 months
                                                  • Evidence of end-organ damage
                                                  • Exclusion of other causes of eosinophilia
                                              • Heart & CNS most commonly involved
                                              • Lungs involved in approximately 40% of patients

                                            IMAGING

                                            • General Features

                                              • Radiographic Findings

                                                • CT Findings

                                                  • Imaging Recommendations

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • Gross Pathologic & Surgical Features

                                                        • Microscopic Features

                                                          CLINICAL ISSUES

                                                          • Presentation

                                                            • Demographics

                                                              • Natural History & Prognosis

                                                                • Treatment

                                                                  Selected References

                                                                  1. Simon D et al: Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract. J Allergy Clin Immunol. 126(1):3-13; quiz 14-5, 2010
                                                                  2. Simon HU et al: Refining the definition of hypereosinophilic syndrome. J Allergy Clin Immunol. 126(1):45-9, 2010
                                                                  3. Peros-Golubicić T et al: Hypereosinophilic syndrome: diagnosis and treatment. Curr Opin Pulm Med. 13(5):422-7, 2007
                                                                  4. Kang EY et al: Pulmonary involvement of idiopathic hypereosinophilic syndrome: CT findings in five patients. J Comput Assist Tomogr. 21(4):612-5, 1997
                                                                  5. Slabbynck H et al: Idiopathic hypereosinophilic syndrome-related pulmonary involvement diagnosed by bronchoalveolar lavage. Chest. 101(4):1178-80, 1992
                                                                  6. Spry CJ et al: Clinical features of fifteen patients with the hypereosinophilic syndrome. Q J Med. 52(205):1-22, 1983
                                                                  7. Epstein DM et al: The hypereosinophilic syndrome. Radiology. 140(1):59-62, 1981