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Hyperparathyroidism
Cheryl A. Petersilge, MD, MBA
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Pathology

        • Diagnostic Checklist

          TERMINOLOGY

          • Abbreviations

            • Hyperparathyroidism (HPTH)
          • Synonyms

            • Advanced osseous changes
              • (von) Recklinghausen disease of bone
              • Osteitis fibrosis cystica
            • Brown tumor: Osteoclastoma
          • Definitions

            • Disease resulting from ↑ parathyroid hormone

          IMAGING

          • General Features

            • Imaging Recommendations

              • Radiographic Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    • Other Modality Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Bandeira F et al: Bone disease in primary hyperparathyroidism. Arq Bras Endocrinol Metabol. 58(5):553-61, 2014
                                      2. Hoang JK et al: How to perform parathyroid 4D CT: tips and traps for technique and interpretation. Radiology. 270(1):15-24, 2014
                                      3. Schwarz P et al: The PRIMARA study: a prospective, descriptive, observational study to review cinacalcet use in patients with primary hyperparathyroidism in clinical practice. Eur J Endocrinol. ePub, 2014
                                      4. Hermoye A et al: F-18 FDG PET/CT as a noninvasive diagnostic and follow-up tool in brown tumors due to secondary hyperparathyroidism. Clin Nucl Med. 34(5):330-2, 2009
                                      5. Lacativa PG et al: Prevalence of radiological findings among cases of severe secondary hyperparathyroidism. Sao Paulo Med J. 127(2):71-7, 2009
                                      6. Levine DS et al: Hybrid SPECT/CT imaging for primary hyperparathyroidism: case reports and pictorial review. Clin Nucl Med. 34(11):779-84, 2009
                                      7. Lew JI et al: Surgical management of primary hyperparathyroidism: state of the art. Surg Clin North Am. 89(5):1205-25, 2009
                                      8. Randall GJ et al: Contrast-enhanced MDCT characteristics of parathyroid adenomas. AJR Am J Roentgenol. 193(2):W139-43, 2009
                                      9. Thurley PD et al: Case report: Rapidly progressive metastatic pulmonary calcification: evolution of changes on CT. Br J Radiol. 82(980):e155-9, 2009
                                      10. Bhadada SK et al: Characteristics of primary hyperparathyroidism in adolescents. J Pediatr Endocrinol Metab. 21(12):1147-53, 2008
                                      11. Agarwal G et al: Recovery pattern of patients with osteitis fibrosa cystica in primary hyperparathyroidism after successful parathyroidectomy. Surgery. 132(6):1075-83; discussion 1083-5, 2002
                                      12. Singhal S et al: Primary hyperparathyroidism: what every orthopedic surgeon should know. Orthopedics. 24(10):1003-9; quiz 1010-1, 2001
                                      13. Genant HK et al: Primary hyperparathyroidism. A comprehensive study of clinical, biochemical and radiographic manifestations. Radiology. 109(3):513-24, 1973
                                      14. Simpson W et al: Skeletal changes in patients on regular hemodialysis. Radiology. 107(2):313-20, 1973
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            • Diagnostic Checklist

                                              TERMINOLOGY

                                              • Abbreviations

                                                • Hyperparathyroidism (HPTH)
                                              • Synonyms

                                                • Advanced osseous changes
                                                  • (von) Recklinghausen disease of bone
                                                  • Osteitis fibrosis cystica
                                                • Brown tumor: Osteoclastoma
                                              • Definitions

                                                • Disease resulting from ↑ parathyroid hormone

                                              IMAGING

                                              • General Features

                                                • Imaging Recommendations

                                                  • Radiographic Findings

                                                    • MR Findings

                                                      • Nuclear Medicine Findings

                                                        • Other Modality Findings

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Microscopic Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Bandeira F et al: Bone disease in primary hyperparathyroidism. Arq Bras Endocrinol Metabol. 58(5):553-61, 2014
                                                                          2. Hoang JK et al: How to perform parathyroid 4D CT: tips and traps for technique and interpretation. Radiology. 270(1):15-24, 2014
                                                                          3. Schwarz P et al: The PRIMARA study: a prospective, descriptive, observational study to review cinacalcet use in patients with primary hyperparathyroidism in clinical practice. Eur J Endocrinol. ePub, 2014
                                                                          4. Hermoye A et al: F-18 FDG PET/CT as a noninvasive diagnostic and follow-up tool in brown tumors due to secondary hyperparathyroidism. Clin Nucl Med. 34(5):330-2, 2009
                                                                          5. Lacativa PG et al: Prevalence of radiological findings among cases of severe secondary hyperparathyroidism. Sao Paulo Med J. 127(2):71-7, 2009
                                                                          6. Levine DS et al: Hybrid SPECT/CT imaging for primary hyperparathyroidism: case reports and pictorial review. Clin Nucl Med. 34(11):779-84, 2009
                                                                          7. Lew JI et al: Surgical management of primary hyperparathyroidism: state of the art. Surg Clin North Am. 89(5):1205-25, 2009
                                                                          8. Randall GJ et al: Contrast-enhanced MDCT characteristics of parathyroid adenomas. AJR Am J Roentgenol. 193(2):W139-43, 2009
                                                                          9. Thurley PD et al: Case report: Rapidly progressive metastatic pulmonary calcification: evolution of changes on CT. Br J Radiol. 82(980):e155-9, 2009
                                                                          10. Bhadada SK et al: Characteristics of primary hyperparathyroidism in adolescents. J Pediatr Endocrinol Metab. 21(12):1147-53, 2008
                                                                          11. Agarwal G et al: Recovery pattern of patients with osteitis fibrosa cystica in primary hyperparathyroidism after successful parathyroidectomy. Surgery. 132(6):1075-83; discussion 1083-5, 2002
                                                                          12. Singhal S et al: Primary hyperparathyroidism: what every orthopedic surgeon should know. Orthopedics. 24(10):1003-9; quiz 1010-1, 2001
                                                                          13. Genant HK et al: Primary hyperparathyroidism. A comprehensive study of clinical, biochemical and radiographic manifestations. Radiology. 109(3):513-24, 1973
                                                                          14. Simpson W et al: Skeletal changes in patients on regular hemodialysis. Radiology. 107(2):313-20, 1973