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Hypoglossal Nerve Schwannoma
C. Douglas Phillips, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Hypoglossal nerve schwannoma (HNS)
            • Synonyms

              • Hypoglossal neurilemmoma, hypoglossal neuroma
            • Definitions

              • Extremely rare, benign tumor of differentiated Schwann cells surrounding CNXII

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Reporting Tips

                                        Selected References

                                        1. Di Pascuale I et al: Hypoglossal nerve schwannoma: case report and literature review. World Neurosurg. 135:205-8, 2020
                                        2. Bindal S et al: Hypoglossal schwannomas: a systematic review of the literature. J Clin Neurosci. 62:162-73, 2019
                                        3. Ram H et al: Hypoglossal schwannoma of parapharyngeal space: an unusual case report. J Maxillofac Oral Surg. 14(Suppl 1):73-6, 2015
                                        4. Nonaka Y et al: Microsurgical management of hypoglossal schwannomas over 3 decades: a modified grading scale to guide surgical approach. Neurosurgery. 69(2 Suppl Operative):ons121-40; discussion ons140, 2011
                                        5. Edizer DT et al: Hypoglossal schwannoma presenting only with headache. J Craniofac Surg. 21(1):261-2, 2010
                                        6. Rachinger J et al: Dumbbell-shaped hypoglossal schwannoma. A case report. Magn Reson Imaging. 21(2):155-8, 2003
                                        7. Sarma S et al: Nonvestibular schwannomas of the brain: a 7-year experience. Neurosurgery. 50(3):437-48; discussion 438-9, 2002
                                        8. Ogawa T et al: A multifocal neurinoma of the hypoglossal nerve with motor paralysis confirmed by electromyography. Int J Oral Maxillofac Surg. 30(2):176-8, 2001
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Hypoglossal nerve schwannoma (HNS)
                                                  • Synonyms

                                                    • Hypoglossal neurilemmoma, hypoglossal neuroma
                                                  • Definitions

                                                    • Extremely rare, benign tumor of differentiated Schwann cells surrounding CNXII

                                                  IMAGING

                                                  • General Features

                                                    • CT Findings

                                                      • MR Findings

                                                        • Imaging Recommendations

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          DIAGNOSTIC CHECKLIST

                                                                          • Consider

                                                                            • Reporting Tips

                                                                              Selected References

                                                                              1. Di Pascuale I et al: Hypoglossal nerve schwannoma: case report and literature review. World Neurosurg. 135:205-8, 2020
                                                                              2. Bindal S et al: Hypoglossal schwannomas: a systematic review of the literature. J Clin Neurosci. 62:162-73, 2019
                                                                              3. Ram H et al: Hypoglossal schwannoma of parapharyngeal space: an unusual case report. J Maxillofac Oral Surg. 14(Suppl 1):73-6, 2015
                                                                              4. Nonaka Y et al: Microsurgical management of hypoglossal schwannomas over 3 decades: a modified grading scale to guide surgical approach. Neurosurgery. 69(2 Suppl Operative):ons121-40; discussion ons140, 2011
                                                                              5. Edizer DT et al: Hypoglossal schwannoma presenting only with headache. J Craniofac Surg. 21(1):261-2, 2010
                                                                              6. Rachinger J et al: Dumbbell-shaped hypoglossal schwannoma. A case report. Magn Reson Imaging. 21(2):155-8, 2003
                                                                              7. Sarma S et al: Nonvestibular schwannomas of the brain: a 7-year experience. Neurosurgery. 50(3):437-48; discussion 438-9, 2002
                                                                              8. Ogawa T et al: A multifocal neurinoma of the hypoglossal nerve with motor paralysis confirmed by electromyography. Int J Oral Maxillofac Surg. 30(2):176-8, 2001