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Head and Neck
Diagnosis
Hypopharynx, Larynx, and Cervical Trachea
Benign and Malignant Tumors
Hypopharynx Carcinoma
Hypopharynx Carcinoma
Philip R. Chapman, MD
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7

OVERVIEW

  • General Comments

    • Classification

      PATHOLOGY

      • Routes of Spread

        • General Features

          • Gross Pathology & Surgical Features

            • Microscopic Features

              IMAGING FINDINGS

              • Detection

                • Staging

                  CLINICAL ISSUES

                  • Presentation

                    • Cancer Natural History & Prognosis

                      • Treatment Options

                        REPORTING CHECKLIST

                        • T Staging

                          • N Staging

                            • M Staging

                              Selected References

                              1. Petersen JF et al: Trends in treatment, incidence and survival of hypopharynx cancer: a 20-year population-based study in the Netherlands. Eur Arch Otorhinolaryngol. 275(1):181-9, 2018
                              2. Amin M.B. et al: AJCC Cancer Staging Manual. 8th Ed. Springer New York, 2017
                              3. Lydiatt WM et al: Head and Neck cancers-major changes in the American Joint Committee on cancer eighth edition cancer staging manual. CA Cancer J Clin. 67(2):122-37, 2017
                              4. Day D et al: Hypopharyngeal cancer: looking back, moving forward. Curr Oncol. 23(4):221-2, 2016
                              5. Wassef HR et al: PET/CT in head-neck Malignancies: the implications for personalized clinical practice. PET Clin. 11(3):219-32, 2016
                              6. Newman JR et al: Survival trends in hypopharyngeal cancer: a population-based review. Laryngoscope. 125(3):624-9, 2015
                              7. Chung EJ et al: Pattern of cervical lymph node metastasis in medial wall pyriform sinus carcinoma. Laryngoscope. 124(4):882-7, 2014
                              8. Kuo P et al: Hypopharyngeal cancer incidence, treatment, and survival: temporal trends in the United States. Laryngoscope. 124(9):2064-9, 2014
                              9. Chen AY et al: Pitfalls in the staging squamous cell carcinoma of the hypopharynx. Neuroimaging Clin N Am. 23(1):67-79, 2013
                              10. Gross BC et al: Level IIB lymph node metastasis in laryngeal and hypopharyngeal squamous cell carcinoma: single-institution case series and review of the literature. Laryngoscope. 123(12):3032-6, 2013
                              11. Takes RP et al: Current trends in initial management of hypopharyngeal cancer: the declining use of open surgery. Head Neck. 34(2):270-81, 2012
                              12. Wang Y et al: Pathways for cervical metastasis in malignant neoplasms of the head and neck region. Clin Anat. 25(1):54-71, 2012
                              13. Becker M et al: Imaging of the larynx and hypopharynx. Eur J Radiol. 66(3):460-79, 2008
                              14. Wycliffe ND et al: Hypopharyngeal cancer. Top Magn Reson Imaging. 18(4):243-58, 2007
                              15. Helliwell TR: Acp best Practice No 169. Evidence based pathology: squamous carcinoma of the hypopharynx. J Clin Pathol. 56(2):81-5, 2003
                              16. Werner JA et al: Functional anatomy of the lymphatic drainage system of the upper aerodigestive tract and its role in metastasis of squamous cell carcinoma. Head Neck. 25(4):322-32, 2003
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              OVERVIEW

                              • General Comments

                                • Classification

                                  PATHOLOGY

                                  • Routes of Spread

                                    • General Features

                                      • Gross Pathology & Surgical Features

                                        • Microscopic Features

                                          IMAGING FINDINGS

                                          • Detection

                                            • Staging

                                              CLINICAL ISSUES

                                              • Presentation

                                                • Cancer Natural History & Prognosis

                                                  • Treatment Options

                                                    REPORTING CHECKLIST

                                                    • T Staging

                                                      • N Staging

                                                        • M Staging

                                                          Selected References

                                                          1. Petersen JF et al: Trends in treatment, incidence and survival of hypopharynx cancer: a 20-year population-based study in the Netherlands. Eur Arch Otorhinolaryngol. 275(1):181-9, 2018
                                                          2. Amin M.B. et al: AJCC Cancer Staging Manual. 8th Ed. Springer New York, 2017
                                                          3. Lydiatt WM et al: Head and Neck cancers-major changes in the American Joint Committee on cancer eighth edition cancer staging manual. CA Cancer J Clin. 67(2):122-37, 2017
                                                          4. Day D et al: Hypopharyngeal cancer: looking back, moving forward. Curr Oncol. 23(4):221-2, 2016
                                                          5. Wassef HR et al: PET/CT in head-neck Malignancies: the implications for personalized clinical practice. PET Clin. 11(3):219-32, 2016
                                                          6. Newman JR et al: Survival trends in hypopharyngeal cancer: a population-based review. Laryngoscope. 125(3):624-9, 2015
                                                          7. Chung EJ et al: Pattern of cervical lymph node metastasis in medial wall pyriform sinus carcinoma. Laryngoscope. 124(4):882-7, 2014
                                                          8. Kuo P et al: Hypopharyngeal cancer incidence, treatment, and survival: temporal trends in the United States. Laryngoscope. 124(9):2064-9, 2014
                                                          9. Chen AY et al: Pitfalls in the staging squamous cell carcinoma of the hypopharynx. Neuroimaging Clin N Am. 23(1):67-79, 2013
                                                          10. Gross BC et al: Level IIB lymph node metastasis in laryngeal and hypopharyngeal squamous cell carcinoma: single-institution case series and review of the literature. Laryngoscope. 123(12):3032-6, 2013
                                                          11. Takes RP et al: Current trends in initial management of hypopharyngeal cancer: the declining use of open surgery. Head Neck. 34(2):270-81, 2012
                                                          12. Wang Y et al: Pathways for cervical metastasis in malignant neoplasms of the head and neck region. Clin Anat. 25(1):54-71, 2012
                                                          13. Becker M et al: Imaging of the larynx and hypopharynx. Eur J Radiol. 66(3):460-79, 2008
                                                          14. Wycliffe ND et al: Hypopharyngeal cancer. Top Magn Reson Imaging. 18(4):243-58, 2007
                                                          15. Helliwell TR: Acp best Practice No 169. Evidence based pathology: squamous carcinoma of the hypopharynx. J Clin Pathol. 56(2):81-5, 2003
                                                          16. Werner JA et al: Functional anatomy of the lymphatic drainage system of the upper aerodigestive tract and its role in metastasis of squamous cell carcinoma. Head Neck. 25(4):322-32, 2003
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