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Idiopathic Pulmonary Hemosiderosis
Allen Heeger, DO
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Idiopathic pulmonary hemosiderosis (IPH)
              • Synonyms

                • Idiopathic pulmonary hemorrhage
              • Definitions

                • Recurrent alveolar hemorrhage without underlying cause
              • Clinical Triad

                • Hemoptysis, iron deficiency anemia, bilateral airspace opacities

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        Selected References

                                        1. LaFreniere K et al: Idiopathic Pulmonary Hemosiderosis 2020
                                        2. Reed AW et al: Lane-Hamilton syndrome: an illustration of extraintestinal manifestations of celiac disease. Clin Pediatr (Phila). 59(13):1195-8, 2020
                                        3. Ross B et al: Disease recurrence after lung transplantation for idiopathic pulmonary hemosiderosis. Respir Med Case Rep. 30:101128, 2020
                                        4. Saha BK: Idiopathic pulmonary hemosiderosis: a state of the art review. Respir Med. 176:106234, 2020
                                        5. Zhang Y et al: Clinical characteristics and prognosis of idiopathic pulmonary hemosiderosis in pediatric patients. J Int Med Res. 47(1):293-302, 2019
                                        6. Scapa JV et al: Diffuse alveolar hemorrhage and pulmonary vasculitides: histopathologic findings. Semin Respir Crit Care Med. 39(4):425-33, 2018
                                        7. Khorashadi L et al: Idiopathic pulmonary haemosiderosis: spectrum of thoracic imaging findings in the adult patient. Clin Radiol. 70(5):459-65, 2015
                                        8. Xi-Yuan C et al: Idiopathic pulmonary hemosiderosis in adults: review of cases reported in the latest 15 years. Clin Respir J. 11(6):677-81, 2015
                                        9. Fishbein GA et al: Lung vasculitis and alveolar hemorrhage: pathology. Semin Respir Crit Care Med. 32(3):254-63, 2011
                                        10. Ioachimescu OC et al: Idiopathic pulmonary haemosiderosis revisited. Eur Respir J. 24(1):162-70, 2004
                                        11. Pedersen FM et al: [Idiopathic pulmonary hemosiderosis.] Ugeskr Laeger. 158(7):902-4, 1996
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Idiopathic pulmonary hemosiderosis (IPH)
                                                    • Synonyms

                                                      • Idiopathic pulmonary hemorrhage
                                                    • Definitions

                                                      • Recurrent alveolar hemorrhage without underlying cause
                                                    • Clinical Triad

                                                      • Hemoptysis, iron deficiency anemia, bilateral airspace opacities

                                                    IMAGING

                                                    • General Features

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Gross Pathologic & Surgical Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              Selected References

                                                                              1. LaFreniere K et al: Idiopathic Pulmonary Hemosiderosis 2020
                                                                              2. Reed AW et al: Lane-Hamilton syndrome: an illustration of extraintestinal manifestations of celiac disease. Clin Pediatr (Phila). 59(13):1195-8, 2020
                                                                              3. Ross B et al: Disease recurrence after lung transplantation for idiopathic pulmonary hemosiderosis. Respir Med Case Rep. 30:101128, 2020
                                                                              4. Saha BK: Idiopathic pulmonary hemosiderosis: a state of the art review. Respir Med. 176:106234, 2020
                                                                              5. Zhang Y et al: Clinical characteristics and prognosis of idiopathic pulmonary hemosiderosis in pediatric patients. J Int Med Res. 47(1):293-302, 2019
                                                                              6. Scapa JV et al: Diffuse alveolar hemorrhage and pulmonary vasculitides: histopathologic findings. Semin Respir Crit Care Med. 39(4):425-33, 2018
                                                                              7. Khorashadi L et al: Idiopathic pulmonary haemosiderosis: spectrum of thoracic imaging findings in the adult patient. Clin Radiol. 70(5):459-65, 2015
                                                                              8. Xi-Yuan C et al: Idiopathic pulmonary hemosiderosis in adults: review of cases reported in the latest 15 years. Clin Respir J. 11(6):677-81, 2015
                                                                              9. Fishbein GA et al: Lung vasculitis and alveolar hemorrhage: pathology. Semin Respir Crit Care Med. 32(3):254-63, 2011
                                                                              10. Ioachimescu OC et al: Idiopathic pulmonary haemosiderosis revisited. Eur Respir J. 24(1):162-70, 2004
                                                                              11. Pedersen FM et al: [Idiopathic pulmonary hemosiderosis.] Ugeskr Laeger. 158(7):902-4, 1996