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Immature Teratoma
Akram M. Shaaban, MBBCh; Evis Sala, MD, PhD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Immature teratoma (IMT)
            • Definitions

              • Malignant form of teratoma containing immature or embryonic tissues
              • Classified as ovarian malignant germ cell tumor (OMGCT)

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Peterson CM et al: Teratomas: a multimodality review. Curr Probl Diagn Radiol. 41(6):210-9, 2012
                                              2. Chabaud-Williamson M et al: Ovarian-sparing surgery for ovarian teratoma in children. Pediatr Blood Cancer. 57(3):429-34, 2011
                                              3. Douay-Hauser N et al: Diagnosis and management of an immature teratoma during ovarian stimulation: a case report. J Med Case Rep. 5:540, 2011
                                              4. Papadias K et al: Teratomas of the ovary: a clinico-pathological evaluation of 87 patients from one institution during a 10-year period. Eur J Gynaecol Oncol. 26(4):446-8, 2005
                                              5. Terzic M et al: Immature ovarian teratoma in a young girl: very short course and lethal outcome. A case report. Int J Gynecol Cancer. 15(2):382-4, 2005
                                              6. Yamaoka T et al: Immature teratoma of the ovary: correlation of MR imaging and pathologic findings. Eur Radiol. 13(2):313-9, 2003
                                              7. Jung SE et al: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22(6):1305-25, 2002
                                              8. Outwater EK et al: Ovarian teratomas: tumor types and imaging characteristics. Radiographics. 21(2):475-90, 2001
                                              9. O'Connor DM et al: The influence of grade on the outcome of stage I ovarian immature (malignant) teratomas and the reproducibility of grading. Int J Gynecol Pathol. 13(4):283-9, 1994
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        TERMINOLOGY

                                                        • Abbreviations

                                                          • Immature teratoma (IMT)
                                                        • Definitions

                                                          • Malignant form of teratoma containing immature or embryonic tissues
                                                          • Classified as ovarian malignant germ cell tumor (OMGCT)

                                                        IMAGING

                                                        • General Features

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Ultrasonographic Findings

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Staging, Grading, & Classification

                                                                          • Gross Pathologic & Surgical Features

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Peterson CM et al: Teratomas: a multimodality review. Curr Probl Diagn Radiol. 41(6):210-9, 2012
                                                                                          2. Chabaud-Williamson M et al: Ovarian-sparing surgery for ovarian teratoma in children. Pediatr Blood Cancer. 57(3):429-34, 2011
                                                                                          3. Douay-Hauser N et al: Diagnosis and management of an immature teratoma during ovarian stimulation: a case report. J Med Case Rep. 5:540, 2011
                                                                                          4. Papadias K et al: Teratomas of the ovary: a clinico-pathological evaluation of 87 patients from one institution during a 10-year period. Eur J Gynaecol Oncol. 26(4):446-8, 2005
                                                                                          5. Terzic M et al: Immature ovarian teratoma in a young girl: very short course and lethal outcome. A case report. Int J Gynecol Cancer. 15(2):382-4, 2005
                                                                                          6. Yamaoka T et al: Immature teratoma of the ovary: correlation of MR imaging and pathologic findings. Eur Radiol. 13(2):313-9, 2003
                                                                                          7. Jung SE et al: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22(6):1305-25, 2002
                                                                                          8. Outwater EK et al: Ovarian teratomas: tumor types and imaging characteristics. Radiographics. 21(2):475-90, 2001
                                                                                          9. O'Connor DM et al: The influence of grade on the outcome of stage I ovarian immature (malignant) teratomas and the reproducibility of grading. Int J Gynecol Pathol. 13(4):283-9, 1994