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Inflammatory Myofibroblastic Tumor
Ethan A. Smith, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Inflammatory myofibroblastic tumor (IMT)
            • Synonyms

              • Inflammatory pseudotumor, plasma cell granuloma, many others
            • Definitions

              • Spindle cell neoplasm with low malignant potential in children & young adults
                • Most common primary lung neoplasm in children

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              CLINICAL ISSUES

                              • Presentation

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Gaudichon J et al: Complete and repeated response of a metastatic ALK-rearranged inflammatory myofibroblastic tumor to crizotinib in a teenage girl. J Pediatr Hematol Oncol. ePub, 2016
                                      2. Antonescu CR et al: Molecular characterization of inflammatory myofibroblastic tumors with frequent ALK and ROS1 gene fusions and rare novel RET rearrangement. Am J Surg Pathol. 39(7):957-67, 2015
                                      3. Chung EM et al: Solid tumors of the peritoneum, omentum, and mesentery in children: radiologic-pathologic correlation: from the radiologic pathology archives. Radiographics. 35(2):521-46, 2015
                                      4. Collin M et al: Inflammatory myofibroblastic tumour of the bladder in children: a review. J Pediatr Urol. 11(5):239-45, 2015
                                      5. Dalton BG et al: Inflammatory myofibroblastic tumors in children. J Pediatr Surg. ePub, 2015
                                      6. Lai LM et al: Shedding light on inflammatory pseudotumor in children: spotlight on inflammatory myofibroblastic tumor. Pediatr Radiol. 45(12):1738-52, 2015
                                      7. Oguz B et al: Imaging of childhood inflammatory myofibroblastic tumor. Pediatr Radiol. 45(11):1672-81, 2015
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Pathology

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Inflammatory myofibroblastic tumor (IMT)
                                                • Synonyms

                                                  • Inflammatory pseudotumor, plasma cell granuloma, many others
                                                • Definitions

                                                  • Spindle cell neoplasm with low malignant potential in children & young adults
                                                    • Most common primary lung neoplasm in children

                                                IMAGING

                                                • General Features

                                                  • CT Findings

                                                    • MR Findings

                                                      • Ultrasonographic Findings

                                                        • Nuclear Medicine Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Gross Pathologic & Surgical Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Gaudichon J et al: Complete and repeated response of a metastatic ALK-rearranged inflammatory myofibroblastic tumor to crizotinib in a teenage girl. J Pediatr Hematol Oncol. ePub, 2016
                                                                          2. Antonescu CR et al: Molecular characterization of inflammatory myofibroblastic tumors with frequent ALK and ROS1 gene fusions and rare novel RET rearrangement. Am J Surg Pathol. 39(7):957-67, 2015
                                                                          3. Chung EM et al: Solid tumors of the peritoneum, omentum, and mesentery in children: radiologic-pathologic correlation: from the radiologic pathology archives. Radiographics. 35(2):521-46, 2015
                                                                          4. Collin M et al: Inflammatory myofibroblastic tumour of the bladder in children: a review. J Pediatr Urol. 11(5):239-45, 2015
                                                                          5. Dalton BG et al: Inflammatory myofibroblastic tumors in children. J Pediatr Surg. ePub, 2015
                                                                          6. Lai LM et al: Shedding light on inflammatory pseudotumor in children: spotlight on inflammatory myofibroblastic tumor. Pediatr Radiol. 45(12):1738-52, 2015
                                                                          7. Oguz B et al: Imaging of childhood inflammatory myofibroblastic tumor. Pediatr Radiol. 45(11):1672-81, 2015