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Gastrointestinal
Diagnosis
Small Intestine
Inflammation
Intestinal (Angioneurotic) Angioedema
Intestinal (Angioneurotic) Angioedema
Atif Zaheer, MD; Michael P. Federle, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Definitions

              • Noninflammatory transient edema of intestinal wall due to ↑ vascular permeability and extravasation of intravascular fluid

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Gross Pathologic & Surgical Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Natural History & Prognosis

                              • Treatment

                                DIAGNOSTIC CHECKLIST

                                • Consider

                                  Selected References

                                  1. Pall AH et al: Clinical features and disease course of primary angioedema patients in a tertiary care hospital. J Asthma Allergy. 13:225-36, 2020
                                  2. Parreira R et al: ACE inhibitor-induced small bowel angioedema, mimicking an acute abdomen. J Surg Case Rep. 2020(10):rjaa348, 2020
                                  3. Banerji A et al: Epidemiology of ACE Inhibitor angioedema utilizing a large electronic health record. J Allergy Clin Immunol Pract. 5(3):744-9, 2017
                                  4. Bernstein JA et al: Effectiveness of ecallantide in treating angiotensin-converting enzyme inhibitor-induced angioedema in the emergency department. Ann Allergy Asthma Immunol. 114(3):245-9, 2015
                                  5. Mutnuri S et al: Visceral angioedema: an under-recognized complication of angiotensin-converting enzyme inhibitors. Postgrad Med. 1-3, 2015
                                  6. Gakhal MS et al: Hereditary angioedema: imaging manifestations and clinical management. Emerg Radiol. 22(1):83-90, 2014
                                  7. Hofman ZL et al: Hereditary angioedema attacks: local swelling at multiple sites. Clin Rev Allergy Immunol.50(1):34-40, 2014
                                  8. Viswanathan C et al: Imaging of complications of oncological therapy in the gastrointestinal system. Cancer Imaging. 12:163-72, 2012
                                  9. Scheirey CD et al: Angiotensin-converting enzyme inhibitor-induced small-bowel angioedema: clinical and imaging findings in 20 patients. AJR Am J Roentgenol. 197(2):393-8, 2011
                                  10. Mukeba D et al: Autoimmune angioneurotic edema in a patient with Helicobacter pylori infection. Helicobacter. 14(1):9-11, 2009
                                  11. Reshef A et al: Hereditary angioedema: new hopes for an orphan disease. Isr Med Assoc J. 10(12):850-5, 2008
                                  12. Wei SC et al: CT findings in small bowel angioedema: a cause of acute abdominal pain. Emerg Radiol. 13(5):281-3, 2007
                                  13. Marmery H et al: Angiotensin-converting enzyme inhibitor-induced visceral angioedema. Clin Radiol. 61(11):979-82, 2006
                                  14. Schmidt TD et al: Angiotensin-converting enzyme inhibitor angioedema of the intestine: a case report and review of the literature. Am J Med Sci. 324(2):106-8, 2002
                                  15. De Backer AI et al: CT of angioedema of the small bowel. AJR Am J Roentgenol. 176(3):649-52, 2001
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  KEY FACTS

                                  • Terminology

                                    • Imaging

                                      • Top Differential Diagnoses

                                        • Pathology

                                          • Clinical Issues

                                            TERMINOLOGY

                                            • Definitions

                                              • Noninflammatory transient edema of intestinal wall due to ↑ vascular permeability and extravasation of intravascular fluid

                                            IMAGING

                                            • General Features

                                              • Radiographic Findings

                                                • CT Findings

                                                  DIFFERENTIAL DIAGNOSIS

                                                    PATHOLOGY

                                                    • General Features

                                                      • Gross Pathologic & Surgical Features

                                                        CLINICAL ISSUES

                                                        • Presentation

                                                          • Demographics

                                                            • Natural History & Prognosis

                                                              • Treatment

                                                                DIAGNOSTIC CHECKLIST

                                                                • Consider

                                                                  Selected References

                                                                  1. Pall AH et al: Clinical features and disease course of primary angioedema patients in a tertiary care hospital. J Asthma Allergy. 13:225-36, 2020
                                                                  2. Parreira R et al: ACE inhibitor-induced small bowel angioedema, mimicking an acute abdomen. J Surg Case Rep. 2020(10):rjaa348, 2020
                                                                  3. Banerji A et al: Epidemiology of ACE Inhibitor angioedema utilizing a large electronic health record. J Allergy Clin Immunol Pract. 5(3):744-9, 2017
                                                                  4. Bernstein JA et al: Effectiveness of ecallantide in treating angiotensin-converting enzyme inhibitor-induced angioedema in the emergency department. Ann Allergy Asthma Immunol. 114(3):245-9, 2015
                                                                  5. Mutnuri S et al: Visceral angioedema: an under-recognized complication of angiotensin-converting enzyme inhibitors. Postgrad Med. 1-3, 2015
                                                                  6. Gakhal MS et al: Hereditary angioedema: imaging manifestations and clinical management. Emerg Radiol. 22(1):83-90, 2014
                                                                  7. Hofman ZL et al: Hereditary angioedema attacks: local swelling at multiple sites. Clin Rev Allergy Immunol.50(1):34-40, 2014
                                                                  8. Viswanathan C et al: Imaging of complications of oncological therapy in the gastrointestinal system. Cancer Imaging. 12:163-72, 2012
                                                                  9. Scheirey CD et al: Angiotensin-converting enzyme inhibitor-induced small-bowel angioedema: clinical and imaging findings in 20 patients. AJR Am J Roentgenol. 197(2):393-8, 2011
                                                                  10. Mukeba D et al: Autoimmune angioneurotic edema in a patient with Helicobacter pylori infection. Helicobacter. 14(1):9-11, 2009
                                                                  11. Reshef A et al: Hereditary angioedema: new hopes for an orphan disease. Isr Med Assoc J. 10(12):850-5, 2008
                                                                  12. Wei SC et al: CT findings in small bowel angioedema: a cause of acute abdominal pain. Emerg Radiol. 13(5):281-3, 2007
                                                                  13. Marmery H et al: Angiotensin-converting enzyme inhibitor-induced visceral angioedema. Clin Radiol. 61(11):979-82, 2006
                                                                  14. Schmidt TD et al: Angiotensin-converting enzyme inhibitor angioedema of the intestine: a case report and review of the literature. Am J Med Sci. 324(2):106-8, 2002
                                                                  15. De Backer AI et al: CT of angioedema of the small bowel. AJR Am J Roentgenol. 176(3):649-52, 2001