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Intracranial Lipoma
Paula J. Woodward, MD
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Clinical Issues

        • Diagnostic Checklist

          TERMINOLOGY

          • Synonyms

            • Lipomatous hamartoma
          • Definitions

            • Mass of mature nonneoplastic adipose tissue
              • CNS lipomas are actually congenital malformations, not true neoplasms

          IMAGING

          • General Features

            • Ultrasonographic Findings

              • MR Findings

                • Imaging Recommendations

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      CLINICAL ISSUES

                      • Presentation

                        • Demographics

                          • Natural History & Prognosis

                            • Treatment

                              DIAGNOSTIC CHECKLIST

                              • Consider

                                Selected References

                                1. Stoll C et al: Associated anomalies in cases with agenesis of the corpus callosum. Am J Med Genet A. 179(10):2101-11, 2019
                                2. Shinar S et al: Fetal pericallosal lipomas - clues to diagnosis in the second trimester. Eur J Paediatr Neurol. 22(6):929-34, 2018
                                3. Atallah A et al: Prenatal diagnosis of pericallosal curvilinear lipoma: specific imaging pattern and diagnostic pitfalls.. Ultrasound Obstet Gynecol. 51(2):269-73, 2018
                                4. Pashaj S et al: Detection of fetal corpus callosum abnormalities by means of 3D ultrasound. Ultraschall Med. 37(2):185-94, 2016
                                5. Gowda VK et al: Ohtahara syndrome associated with hemimegalencephaly and intracranial lipoma. J Pediatr Neurosci. 10(2):185-7, 2015
                                6. Nanni M et al: Prenatal and postnatal imaging of multiple intracranial lipomas: report of a case. Fetal Diagn Ther. 30(2):160-2, 2011
                                7. Takatani T et al: A posterior fossa lipoma extending into the cervical spine and subcutaneous space via a cranium bifidum. Brain Dev. 30(9):603-5, 2008
                                8. Woodward PJ et al: From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation. Radiographics. 25(1):215-42, 2005
                                9. Puvabanditsin S et al: Intracranial lipomas in neonate. J Perinatol. 22(5):414-5, 2002
                                10. Ickowitz V et al: Prenatal diagnosis and postnatal follow-up of pericallosal lipoma: report of seven new cases. AJNR Am J Neuroradiol. 22(4):767-72, 2001
                                11. Kieslich M et al: Midline developmental anomalies with lipomas in the corpus callosum region. J Child Neurol. 15(2):85-9, 2000
                                Related Anatomy
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                                Related Differential Diagnoses
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                                References
                                Tables

                                Tables

                                KEY FACTS

                                • Imaging

                                  • Top Differential Diagnoses

                                    • Clinical Issues

                                      • Diagnostic Checklist

                                        TERMINOLOGY

                                        • Synonyms

                                          • Lipomatous hamartoma
                                        • Definitions

                                          • Mass of mature nonneoplastic adipose tissue
                                            • CNS lipomas are actually congenital malformations, not true neoplasms

                                        IMAGING

                                        • General Features

                                          • Ultrasonographic Findings

                                            • MR Findings

                                              • Imaging Recommendations

                                                DIFFERENTIAL DIAGNOSIS

                                                  PATHOLOGY

                                                  • General Features

                                                    CLINICAL ISSUES

                                                    • Presentation

                                                      • Demographics

                                                        • Natural History & Prognosis

                                                          • Treatment

                                                            DIAGNOSTIC CHECKLIST

                                                            • Consider

                                                              Selected References

                                                              1. Stoll C et al: Associated anomalies in cases with agenesis of the corpus callosum. Am J Med Genet A. 179(10):2101-11, 2019
                                                              2. Shinar S et al: Fetal pericallosal lipomas - clues to diagnosis in the second trimester. Eur J Paediatr Neurol. 22(6):929-34, 2018
                                                              3. Atallah A et al: Prenatal diagnosis of pericallosal curvilinear lipoma: specific imaging pattern and diagnostic pitfalls.. Ultrasound Obstet Gynecol. 51(2):269-73, 2018
                                                              4. Pashaj S et al: Detection of fetal corpus callosum abnormalities by means of 3D ultrasound. Ultraschall Med. 37(2):185-94, 2016
                                                              5. Gowda VK et al: Ohtahara syndrome associated with hemimegalencephaly and intracranial lipoma. J Pediatr Neurosci. 10(2):185-7, 2015
                                                              6. Nanni M et al: Prenatal and postnatal imaging of multiple intracranial lipomas: report of a case. Fetal Diagn Ther. 30(2):160-2, 2011
                                                              7. Takatani T et al: A posterior fossa lipoma extending into the cervical spine and subcutaneous space via a cranium bifidum. Brain Dev. 30(9):603-5, 2008
                                                              8. Woodward PJ et al: From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation. Radiographics. 25(1):215-42, 2005
                                                              9. Puvabanditsin S et al: Intracranial lipomas in neonate. J Perinatol. 22(5):414-5, 2002
                                                              10. Ickowitz V et al: Prenatal diagnosis and postnatal follow-up of pericallosal lipoma: report of seven new cases. AJNR Am J Neuroradiol. 22(4):767-72, 2001
                                                              11. Kieslich M et al: Midline developmental anomalies with lipomas in the corpus callosum region. J Child Neurol. 15(2):85-9, 2000