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Intracranial Lipoma
A. James Barkovich, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Diagnostic Checklist

          TERMINOLOGY

          • Abbreviations

            • Intracranial lipoma (ICL)
          • Synonyms

            • Lipomatous hamartoma
          • Definitions

            • Mass of mature nonneoplastic adipose tissue
              • CNS lipomas are congenital malformations, not true neoplasms
              • Lipoma variants in CNS include angiolipoma, hibernoma, osteolipoma

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Gossner J: Small intracranial lipomas may be a frequent finding on computed tomography of the brain. A case series. Neuroradiol J. 26(1):27-9, 2013
                                          2. Nanni M et al: Prenatal and postnatal imaging of multiple intracranial lipomas: report of a case. Fetal Diagn Ther. 30(2):160-2, 2011
                                          3. Jabot G et al: Intracranial lipomas: clinical appearances on neuroimaging and clinical significance. J Neurol. 256(6):851-5, 2009
                                          4. Moog U: Encephalocraniocutaneous lipomatosis. J Med Genet. 46(11):721-9, 2009
                                          5. Kemmling A et al: A diagnostic pitfall for intracranial aneurysms in time-of-flight MR angiography: small intracranial lipomas. AJR Am J Roentgenol. 190(1):W62-7, 2008
                                          6. Loddenkemper T et al: Intracranial lipomas and epilepsy. J Neurol. 253(5):590-3, 2006
                                          7. Yildiz H et al: Intracranial lipomas: importance of localization. Neuroradiology. 48(1):1-7, 2006
                                          8. Gaskin CM et al: Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses. AJR Am J Roentgenol. 182(3):733-9, 2004
                                          9. Kurt G et al: Hypothalamic lipoma adjacent to mamillary bodies. Childs Nerv Syst. 18(12):732-4, 2002
                                          10. Tankéré F et al: Cerebellopontine angle lipomas: report of four cases and review of the literature. Neurosurgery. 50(3):626-31; discussion 631-2, 2002
                                          11. Feldman RP et al: Intracranial lipoma of the sylvian fissure. Case report and review of the literature. J Neurosurg. 94(3):515-9, 2001
                                          12. Ickowitz V et al: Prenatal diagnosis and postnatal follow-up of pericallosal lipoma: report of seven new cases. AJNR Am J Neuroradiol. 22(4):767-72, 2001
                                          13. Amor DJ et al: Encephalocraniocutaneous lipomatosis (Fishman syndrome): a rare neurocutaneous syndrome. J Paediatr Child Health. 36(6):603-5, 2000
                                          14. Kieslich M et al: Midline developmental anomalies with lipomas in the corpus callosum region. J Child Neurol. 15(2):85-9, 2000
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Intracranial lipoma (ICL)
                                                  • Synonyms

                                                    • Lipomatous hamartoma
                                                  • Definitions

                                                    • Mass of mature nonneoplastic adipose tissue
                                                      • CNS lipomas are congenital malformations, not true neoplasms
                                                      • Lipoma variants in CNS include angiolipoma, hibernoma, osteolipoma

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Gossner J: Small intracranial lipomas may be a frequent finding on computed tomography of the brain. A case series. Neuroradiol J. 26(1):27-9, 2013
                                                                                  2. Nanni M et al: Prenatal and postnatal imaging of multiple intracranial lipomas: report of a case. Fetal Diagn Ther. 30(2):160-2, 2011
                                                                                  3. Jabot G et al: Intracranial lipomas: clinical appearances on neuroimaging and clinical significance. J Neurol. 256(6):851-5, 2009
                                                                                  4. Moog U: Encephalocraniocutaneous lipomatosis. J Med Genet. 46(11):721-9, 2009
                                                                                  5. Kemmling A et al: A diagnostic pitfall for intracranial aneurysms in time-of-flight MR angiography: small intracranial lipomas. AJR Am J Roentgenol. 190(1):W62-7, 2008
                                                                                  6. Loddenkemper T et al: Intracranial lipomas and epilepsy. J Neurol. 253(5):590-3, 2006
                                                                                  7. Yildiz H et al: Intracranial lipomas: importance of localization. Neuroradiology. 48(1):1-7, 2006
                                                                                  8. Gaskin CM et al: Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses. AJR Am J Roentgenol. 182(3):733-9, 2004
                                                                                  9. Kurt G et al: Hypothalamic lipoma adjacent to mamillary bodies. Childs Nerv Syst. 18(12):732-4, 2002
                                                                                  10. Tankéré F et al: Cerebellopontine angle lipomas: report of four cases and review of the literature. Neurosurgery. 50(3):626-31; discussion 631-2, 2002
                                                                                  11. Feldman RP et al: Intracranial lipoma of the sylvian fissure. Case report and review of the literature. J Neurosurg. 94(3):515-9, 2001
                                                                                  12. Ickowitz V et al: Prenatal diagnosis and postnatal follow-up of pericallosal lipoma: report of seven new cases. AJNR Am J Neuroradiol. 22(4):767-72, 2001
                                                                                  13. Amor DJ et al: Encephalocraniocutaneous lipomatosis (Fishman syndrome): a rare neurocutaneous syndrome. J Paediatr Child Health. 36(6):603-5, 2000
                                                                                  14. Kieslich M et al: Midline developmental anomalies with lipomas in the corpus callosum region. J Child Neurol. 15(2):85-9, 2000