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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Definitions
Mass within (usually dilated) duct
Overlap with intracystic masses, which typically occur in lactiferous or terminal ducts
Ductography: Injection of discharging duct with small volume of contrast followed by magnification craniocaudal and 90° lateral views
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
Ductography
MR Findings
CT Findings
Imaging Recommendations
Nuclear Medicine Findings
Image-Guided Biopsy
DIFFERENTIAL DIAGNOSIS
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Guo Y et al: Retroareolar masses and intraductal abnormalities detected on screening ultrasound: can biopsy be avoided? Br J Radiol. 20170816, 2018
Kim WH et al: Intraductal mass on breast ultrasound: final outcomes and predictors of malignancy. AJR Am J Roentgenol. 200(4):932-7, 2013
Ferris-James DM et al: Imaging approaches to diagnosis and management of common ductal abnormalities. Radiographics. 32(4):1009-30, 2012
Lu Q et al: Surgical excision of intraductal breast papilloma diagnosed on core biopsy. ANZ J Surg. 82(3):168-72, 2012
Chang JM et al: Management of ultrasonographically detected benign papillomas of the breast at core needle biopsy. AJR Am J Roentgenol. 196(3):723-9, 2011
Chang JM et al: Papillary lesions initially diagnosed at ultrasound-guided vacuum-assisted breast biopsy: rate of malignancy based on subsequent surgical excision. Ann Surg Oncol. 18(9):2506-14, 2011
Richter-Ehrenstein C et al: Intraductal papillomas of the breast: diagnosis and management of 151 patients. Breast. 20(6):501-4, 2011
Tominaga J et al: Magnetic resonance imaging of intraductal papillomas of the breast. J Comput Assist Tomogr. 35(1):153-7, 2011
Chang CB et al: Solitary dilated duct identified at mammography: outcomes analysis. AJR Am J Roentgenol. 194(2):378-82, 2010
Jung SY et al: Risk factors for malignancy in benign papillomas of the breast on core needle biopsy. World J Surg. 34(2):261-5, 2010
Ahmadiyeh N et al: Management of intraductal papillomas of the breast: an analysis of 129 cases and their outcome. Ann Surg Oncol. 16(8):2264-9, 2009
Chang JM et al: Does ultrasound-guided directional vacuum-assisted removal help eliminate abnormal nipple discharge in patients with benign intraductal single mass? Korean J Radiol. 10(6):575-80, 2009
Ganesan S et al: Ultrasound spectrum in intraductal papillary neoplasms of breast. Br J Radiol. 79(946):843-9, 2006
Liberman L et al: Is surgical excision warranted after benign, concordant diagnosis of papilloma at percutaneous breast biopsy? AJR Am J Roentgenol. 186(5):1328-34, 2006
Mercado CL et al: Papillary lesions of the breast at percutaneous core-needle biopsy. Radiology. 238(3):801-8, 2006
Valdes EK et al: Significance of papillary lesions at percutaneous breast biopsy. Ann Surg Oncol. 13(4):480-2, 2006
Dennis MA et al: Incidental treatment of nipple discharge caused by benign intraductal papilloma through diagnostic Mammotome biopsy. AJR Am J Roentgenol. 174(5):1263-8, 2000
Orel SG et al: MR imaging in patients with nipple discharge: initial experience. Radiology. 216(1):248-54, 2000
Hild F et al: Ductal orientated sonography improves the diagnosis of pathological nipple discharge of the female breast compared with galactography. Eur J Cancer Prev. 7 Suppl 1:S57-62, 1998
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Definitions
Mass within (usually dilated) duct
Overlap with intracystic masses, which typically occur in lactiferous or terminal ducts
Ductography: Injection of discharging duct with small volume of contrast followed by magnification craniocaudal and 90° lateral views
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
Ductography
MR Findings
CT Findings
Imaging Recommendations
Nuclear Medicine Findings
Image-Guided Biopsy
DIFFERENTIAL DIAGNOSIS
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Guo Y et al: Retroareolar masses and intraductal abnormalities detected on screening ultrasound: can biopsy be avoided? Br J Radiol. 20170816, 2018
Kim WH et al: Intraductal mass on breast ultrasound: final outcomes and predictors of malignancy. AJR Am J Roentgenol. 200(4):932-7, 2013
Ferris-James DM et al: Imaging approaches to diagnosis and management of common ductal abnormalities. Radiographics. 32(4):1009-30, 2012
Lu Q et al: Surgical excision of intraductal breast papilloma diagnosed on core biopsy. ANZ J Surg. 82(3):168-72, 2012
Chang JM et al: Management of ultrasonographically detected benign papillomas of the breast at core needle biopsy. AJR Am J Roentgenol. 196(3):723-9, 2011
Chang JM et al: Papillary lesions initially diagnosed at ultrasound-guided vacuum-assisted breast biopsy: rate of malignancy based on subsequent surgical excision. Ann Surg Oncol. 18(9):2506-14, 2011
Richter-Ehrenstein C et al: Intraductal papillomas of the breast: diagnosis and management of 151 patients. Breast. 20(6):501-4, 2011
Tominaga J et al: Magnetic resonance imaging of intraductal papillomas of the breast. J Comput Assist Tomogr. 35(1):153-7, 2011
Chang CB et al: Solitary dilated duct identified at mammography: outcomes analysis. AJR Am J Roentgenol. 194(2):378-82, 2010
Jung SY et al: Risk factors for malignancy in benign papillomas of the breast on core needle biopsy. World J Surg. 34(2):261-5, 2010
Ahmadiyeh N et al: Management of intraductal papillomas of the breast: an analysis of 129 cases and their outcome. Ann Surg Oncol. 16(8):2264-9, 2009
Chang JM et al: Does ultrasound-guided directional vacuum-assisted removal help eliminate abnormal nipple discharge in patients with benign intraductal single mass? Korean J Radiol. 10(6):575-80, 2009
Ganesan S et al: Ultrasound spectrum in intraductal papillary neoplasms of breast. Br J Radiol. 79(946):843-9, 2006
Liberman L et al: Is surgical excision warranted after benign, concordant diagnosis of papilloma at percutaneous breast biopsy? AJR Am J Roentgenol. 186(5):1328-34, 2006
Mercado CL et al: Papillary lesions of the breast at percutaneous core-needle biopsy. Radiology. 238(3):801-8, 2006
Valdes EK et al: Significance of papillary lesions at percutaneous breast biopsy. Ann Surg Oncol. 13(4):480-2, 2006
Dennis MA et al: Incidental treatment of nipple discharge caused by benign intraductal papilloma through diagnostic Mammotome biopsy. AJR Am J Roentgenol. 174(5):1263-8, 2000
Orel SG et al: MR imaging in patients with nipple discharge: initial experience. Radiology. 216(1):248-54, 2000
Hild F et al: Ductal orientated sonography improves the diagnosis of pathological nipple discharge of the female breast compared with galactography. Eur J Cancer Prev. 7 Suppl 1:S57-62, 1998
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