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Intralobar Sequestration
Melissa L. Rosado-de-Christenson, MD, FACR; Tyler H. Ternes, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Intralobar sequestration (ILS)
              • Definitions

                • From Latin "sequestrare" (to be separated)
                • Intralobar sequestration (~ 75%)
                  • Shares visceral pleura of affected lobe
                • Pulmonary sequestration
                  • No normal communication with tracheobronchial tree
                  • Systemic blood supply
                • Extralobar sequestration (~ 25%)
                  • Supernumerary lung tissue
                  • Separate pleural investment
                • Bronchopulmonary foregut malformation
                  • Pulmonary sequestration (ELS or ILS) with foregut communication (esophagus, stomach) (rare)

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Angiographic Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            Selected References

                                            1. Wei Y et al: Pulmonary sequestration: a retrospective analysis of 2625 cases in China. Eur J Cardiothorac Surg. 40(1):e39-42, 2011
                                            2. Biyyam DR et al: Congenital lung abnormalities: embryologic features, prenatal diagnosis, and postnatal radiologic-pathologic correlation. Radiographics. 30(6):1721-38, 2010
                                            3. Lee EY et al: Multidetector CT evaluation of congenital lung anomalies. Radiology. 247(3):632-48, 2008
                                            4. Newman B: Congenital bronchopulmonary foregut malformations: concepts and controversies. Pediatr Radiol. 36(8):773-91, 2006
                                            5. Corbett HJ et al: Pulmonary sequestration. Paediatr Respir Rev. 5(1):59-68, 2004
                                            6. Zylak CJ et al: Developmental lung anomalies in the adult: radiologic-pathologic correlation. Radiographics. 22 Spec No:S25-43, 2002
                                            7. Bratu I et al: The multiple facets of pulmonary sequestration. J Pediatr Surg. 36(5):784-90, 2001
                                            8. Do KH et al: Systemic arterial supply to the lungs in adults: spiral CT findings. Radiographics. 21(2):387-402, 2001
                                            9. Saygi A: Intralobar pulmonary sequestration. Chest. 119(3):990-2, 2001
                                            10. Frazier AA et al: Intralobar sequestration: radiologic-pathologic correlation. Radiographics. 17(3):725-45, 1997
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Abbreviations

                                                          • Intralobar sequestration (ILS)
                                                        • Definitions

                                                          • From Latin "sequestrare" (to be separated)
                                                          • Intralobar sequestration (~ 75%)
                                                            • Shares visceral pleura of affected lobe
                                                          • Pulmonary sequestration
                                                            • No normal communication with tracheobronchial tree
                                                            • Systemic blood supply
                                                          • Extralobar sequestration (~ 25%)
                                                            • Supernumerary lung tissue
                                                            • Separate pleural investment
                                                          • Bronchopulmonary foregut malformation
                                                            • Pulmonary sequestration (ELS or ILS) with foregut communication (esophagus, stomach) (rare)

                                                        IMAGING

                                                        • General Features

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Angiographic Findings

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Gross Pathologic & Surgical Features

                                                                          • Microscopic Features

                                                                            CLINICAL ISSUES

                                                                            • Presentation

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Consider

                                                                                      Selected References

                                                                                      1. Wei Y et al: Pulmonary sequestration: a retrospective analysis of 2625 cases in China. Eur J Cardiothorac Surg. 40(1):e39-42, 2011
                                                                                      2. Biyyam DR et al: Congenital lung abnormalities: embryologic features, prenatal diagnosis, and postnatal radiologic-pathologic correlation. Radiographics. 30(6):1721-38, 2010
                                                                                      3. Lee EY et al: Multidetector CT evaluation of congenital lung anomalies. Radiology. 247(3):632-48, 2008
                                                                                      4. Newman B: Congenital bronchopulmonary foregut malformations: concepts and controversies. Pediatr Radiol. 36(8):773-91, 2006
                                                                                      5. Corbett HJ et al: Pulmonary sequestration. Paediatr Respir Rev. 5(1):59-68, 2004
                                                                                      6. Zylak CJ et al: Developmental lung anomalies in the adult: radiologic-pathologic correlation. Radiographics. 22 Spec No:S25-43, 2002
                                                                                      7. Bratu I et al: The multiple facets of pulmonary sequestration. J Pediatr Surg. 36(5):784-90, 2001
                                                                                      8. Do KH et al: Systemic arterial supply to the lungs in adults: spiral CT findings. Radiographics. 21(2):387-402, 2001
                                                                                      9. Saygi A: Intralobar pulmonary sequestration. Chest. 119(3):990-2, 2001
                                                                                      10. Frazier AA et al: Intralobar sequestration: radiologic-pathologic correlation. Radiographics. 17(3):725-45, 1997