Santiago Martínez-Jiménez, MD; Carlos S. Restrepo, MD; Brett W. Carter, MD
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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Kaposi sarcoma (KS)
Acquired immune deficiency syndrome with Kaposi sarcoma (AIDS-KS): Epidemic KS
Iatrogenic Kaposi sarcoma (IKS)
Definitions
Low-grade mesenchymal neoplasm of blood and lymphatic vessels, primarily affecting skin
Can cause disseminated disease in variety of organs: Lymphatic system, lungs, airways, abdominal viscera, etc.
AIDS-KS: KS related to human immunodeficiency virus (HIV)/AIDS
IKS: KS related to immunosuppression
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Gramolelli S et al: The role of Kaposi sarcoma-associated herpesvirus in the pathogenesis of Kaposi sarcoma. J Pathol. 235(2):368-80, 2015
Mankia SK et al: The response of HIV-associated lymphadenopathic Kaposi sarcoma to highly active antiretroviral therapy evaluated by 18F-FDG PET/CT. Clin Nucl Med. 37(7):692-3, 2012
van de Luijtgaarden A et al: Imaging of HIV-associated Kaposi sarcoma; F-18-FDG-PET/CT and In-111-bevacizumabscintigraphy. J Acquir Immune Defic Syndr. 54(4):444-6, 2010
Gasparetto TD et al: Pulmonary involvement in Kaposi sarcoma: correlation between imaging and pathology. Orphanet J Rare Dis. 4:18, 2009
Martinez S et al: Kaposi sarcoma after bilateral lung transplantation. J Thorac Imaging. 23(1):50-3, 2008
Restrepo CS et al: Imaging manifestations of Kaposi sarcoma. Radiographics. 26(4):1169-85, 2006
Cheung MC et al: AIDS-related malignancies: emerging challenges in the era of highly active antiretroviral therapy. Oncologist. 10(6):412-26, 2005
Boiselle PM et al: Update on lung disease in AIDS. Semin Roentgenol. 37(1):54-71, 2002
Moore EH et al: Bacillary angiomatosis in patients with AIDS: multiorgan imaging findings. Radiology. 197(1):67-72, 1995
Sivit CJ et al: Kaposi's sarcoma of the lung in AIDS: radiologic-pathologic analysis. AJR Am J Roentgenol. 148(1):25-8, 1987
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Kaposi sarcoma (KS)
Acquired immune deficiency syndrome with Kaposi sarcoma (AIDS-KS): Epidemic KS
Iatrogenic Kaposi sarcoma (IKS)
Definitions
Low-grade mesenchymal neoplasm of blood and lymphatic vessels, primarily affecting skin
Can cause disseminated disease in variety of organs: Lymphatic system, lungs, airways, abdominal viscera, etc.
AIDS-KS: KS related to human immunodeficiency virus (HIV)/AIDS
IKS: KS related to immunosuppression
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Gramolelli S et al: The role of Kaposi sarcoma-associated herpesvirus in the pathogenesis of Kaposi sarcoma. J Pathol. 235(2):368-80, 2015
Mankia SK et al: The response of HIV-associated lymphadenopathic Kaposi sarcoma to highly active antiretroviral therapy evaluated by 18F-FDG PET/CT. Clin Nucl Med. 37(7):692-3, 2012
van de Luijtgaarden A et al: Imaging of HIV-associated Kaposi sarcoma; F-18-FDG-PET/CT and In-111-bevacizumabscintigraphy. J Acquir Immune Defic Syndr. 54(4):444-6, 2010
Gasparetto TD et al: Pulmonary involvement in Kaposi sarcoma: correlation between imaging and pathology. Orphanet J Rare Dis. 4:18, 2009
Martinez S et al: Kaposi sarcoma after bilateral lung transplantation. J Thorac Imaging. 23(1):50-3, 2008
Restrepo CS et al: Imaging manifestations of Kaposi sarcoma. Radiographics. 26(4):1169-85, 2006
Cheung MC et al: AIDS-related malignancies: emerging challenges in the era of highly active antiretroviral therapy. Oncologist. 10(6):412-26, 2005
Boiselle PM et al: Update on lung disease in AIDS. Semin Roentgenol. 37(1):54-71, 2002
Moore EH et al: Bacillary angiomatosis in patients with AIDS: multiorgan imaging findings. Radiology. 197(1):67-72, 1995
Sivit CJ et al: Kaposi's sarcoma of the lung in AIDS: radiologic-pathologic analysis. AJR Am J Roentgenol. 148(1):25-8, 1987
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