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Klippel-Trenaunay-Weber Syndrome
Catherine C. Roberts, MD
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KEY FACTS

  • Imaging

    • Clinical Issues

      TERMINOLOGY

      • Abbreviations

        • Klippel-Trenaunay-Weber (KTW)
      • Synonyms

        • Angio-osteohypertrophy syndrome, Klippel-Trenaunay syndrome, nevus vasculosus osteohypertrophicus

      IMAGING

      • General Features

        • Imaging Recommendations

          • Common Multimodality Findings

            • Less Common Multimodality Findings

              • Ultrasonographic Findings

                • Nuclear Medicine Findings

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Microscopic Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Treatment

                              Selected References

                              1. Luks VL et al: Lymphatic and other vascular malformative/overgrowth disorders are caused by somatic mutations in PIK3CA. J Pediatr. 166(4):1048-54.e1-5, 2015
                              2. Sung HM et al: Clinical experience of the Klippel-Trenaunay syndrome. Arch Plast Surg. 42(5):552-8, 2015
                              3. Lacerda Lda S et al: Differential diagnoses of overgrowth syndromes: the most important clinical and radiological disease manifestations. Radiol Res Pract. 2014:947451, 2014
                              4. Uller W et al: Overgrowth syndromes with complex vascular anomalies. Semin Pediatr Surg. 23(4):208-15, 2014
                              5. Lachman RS et al: Klippel-Trenaunay syndrome. In Lachman RS et al: Taybi and Lachman's Radiology of Syndromes, Metabolic Disorders and Skeletal Dysplasias. 5th ed. Philadelphia: Mosby Elsevier. 440-1, 2007
                              6. Kransdorf MJ et al: Vascular and lymphatic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 173, 2006
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              KEY FACTS

                              • Imaging

                                • Clinical Issues

                                  TERMINOLOGY

                                  • Abbreviations

                                    • Klippel-Trenaunay-Weber (KTW)
                                  • Synonyms

                                    • Angio-osteohypertrophy syndrome, Klippel-Trenaunay syndrome, nevus vasculosus osteohypertrophicus

                                  IMAGING

                                  • General Features

                                    • Imaging Recommendations

                                      • Common Multimodality Findings

                                        • Less Common Multimodality Findings

                                          • Ultrasonographic Findings

                                            • Nuclear Medicine Findings

                                              DIFFERENTIAL DIAGNOSIS

                                                PATHOLOGY

                                                • General Features

                                                  • Microscopic Features

                                                    CLINICAL ISSUES

                                                    • Presentation

                                                      • Demographics

                                                        • Treatment

                                                          Selected References

                                                          1. Luks VL et al: Lymphatic and other vascular malformative/overgrowth disorders are caused by somatic mutations in PIK3CA. J Pediatr. 166(4):1048-54.e1-5, 2015
                                                          2. Sung HM et al: Clinical experience of the Klippel-Trenaunay syndrome. Arch Plast Surg. 42(5):552-8, 2015
                                                          3. Lacerda Lda S et al: Differential diagnoses of overgrowth syndromes: the most important clinical and radiological disease manifestations. Radiol Res Pract. 2014:947451, 2014
                                                          4. Uller W et al: Overgrowth syndromes with complex vascular anomalies. Semin Pediatr Surg. 23(4):208-15, 2014
                                                          5. Lachman RS et al: Klippel-Trenaunay syndrome. In Lachman RS et al: Taybi and Lachman's Radiology of Syndromes, Metabolic Disorders and Skeletal Dysplasias. 5th ed. Philadelphia: Mosby Elsevier. 440-1, 2007
                                                          6. Kransdorf MJ et al: Vascular and lymphatic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 173, 2006