Membranous labyrinth ossification as healing response to infectious, inflammatory, traumatic, or surgical insult to inner ear
IMAGING
General Features
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Orman G et al: Accuracy of MR imaging for detection of sensorineural hearing loss in infants with bacterial meningitis. AJNR Am J Neuroradiol. 41(6):1081-6, 2020
Chandrasekhar SS et al: Clinical practice guideline: sudden hearing loss (update) executive summary. Otolaryngol Head Neck Surg. 161(2):195-210, 2019
Bloch SL et al: Labyrinthitis ossificans: on the mechanism of perilabyrinthine bone remodeling. Ann Otol Rhinol Laryngol. 124(8):649-54, 2015
Jiang ZY et al: Utility of MRIs in adult cochlear implant evaluations. Otol Neurotol. 35(9):1533-5, 2014
Lin HY et al: The incidence of tympanogenic labyrinthitis ossificans. J Laryngol Otol. 128(7):618-20, 2014
Young JY et al: Preoperative imaging of sensorineural hearing loss in pediatric candidates for cochlear implantation. Radiographics. 34(5):E133-49, 2014
Kopelovich JC et al: Early prediction of postmeningitic hearing loss in children using magnetic resonance imaging. Arch Otolaryngol Head Neck Surg. 137(5):441-7, 2011
Durisin M et al: Cochlear osteoneogenesis after meningitis in cochlear implant patients: a retrospective analysis. Otol Neurotol. 31(7):1072-8, 2010
Philippon D et al: Cochlear implantation in postmeningitic deafness. Otol Neurotol. 31(1):83-7, 2010
Saito N et al: Clinical and radiologic manifestations of sickle cell disease in the head and neck. Radiographics. 30(4):1021-34, 2010
Isaacson B et al: Labyrinthitis ossificans: how accurate is MRI in predicting cochlear obstruction? Otolaryngol Head Neck Surg. 140(5):692-6, 2009
Liu BP et al: Labyrinthitis ossificans in a child with sickle cell disease: CT and MRI findings. Pediatr Radiol. 39(9):999-1001, 2009
Ozgen B et al: Complete labyrinthine aplasia: clinical and radiologic findings with review of the literature. AJNR Am J Neuroradiol. 30(4):774-80, 2009
Berrettini S et al: Scala vestibuli cochlear implantation in patients with partially ossified cochleas. J Laryngol Otol. 116(11):946-50, 2002
Glastonbury CM et al: Imaging findings of cochlear nerve deficiency. AJNR Am J Neuroradiol. 23(4):635-43, 2002
Thomas J et al: Evaluation of cochlear implantation in post-meningitic adults. J Laryngol Otol Suppl. 24:27-33, 1999
Muren C et al: Postmeningitic labyrinthine ossification primarily affecting the semicircular canals. Eur Radiol. 7(2):208-13, 1997
Johnson MH et al: CT of postmeningitic deafness: observations and predictive value of cochlear implants in children. AJNR. 16(1):103-9, 1995
Silberman B et al: Role of modern imaging technology in the implementation of pediatric cochlear implants. Ann Otol Rhinol Laryngol. 104(1):42-6, 1995
deSouza C et al: Pathology of labyrinthine ossification. J Laryngol Otol. 105(8):621-4, 1991
Novak MA et al: Labyrinthine ossification after meningitis: its implications for cochlear implantation. Otolaryngol Head Neck Surg. 103(3):351-6, 1990
Steenerson RL et al: Scala vestibuli cochlear implantation for labyrinthine ossification. Am J Otol. 11(5):360-3, 1990
Harnsberger HR et al: Cochlear implant candidates: assessment with CT and MR imaging. Radiology. 164(1):53-7, 1987
Kotzias SA et al: Labyrinthine ossification: differences between two types of ectopic bone. Am J Otol. 6(6):490-4, 1985
Swartz JD et al: Labyrinthine ossification: etiologies and CT findings. Radiology. 157(2):395-8, 1985
Becker TS et al: Labyrinthine ossification secondary to childhood bacterial meningitis: implications for cochlear implant surgery. AJNR Am J Neuroradiol. 5(6):739-41, 1984
Ibrahim RA et al: Labyrinthine ossificans and cochlear implants. Arch Otolaryngol. 106(2):111-3, 1980
Hoffman RA et al: Radiologic diagnosis of labyrinthitis ossificans. Ann Otol Rhinol Laryngol. 88(2 Pt 1):253-7, 1979
Suga F et al: Labyrinthitis ossificans. Ann Otol Rhinol Laryngol. 86(1 Pt 1):17-29, 1977
Membranous labyrinth ossification as healing response to infectious, inflammatory, traumatic, or surgical insult to inner ear
IMAGING
General Features
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Orman G et al: Accuracy of MR imaging for detection of sensorineural hearing loss in infants with bacterial meningitis. AJNR Am J Neuroradiol. 41(6):1081-6, 2020
Chandrasekhar SS et al: Clinical practice guideline: sudden hearing loss (update) executive summary. Otolaryngol Head Neck Surg. 161(2):195-210, 2019
Bloch SL et al: Labyrinthitis ossificans: on the mechanism of perilabyrinthine bone remodeling. Ann Otol Rhinol Laryngol. 124(8):649-54, 2015
Jiang ZY et al: Utility of MRIs in adult cochlear implant evaluations. Otol Neurotol. 35(9):1533-5, 2014
Lin HY et al: The incidence of tympanogenic labyrinthitis ossificans. J Laryngol Otol. 128(7):618-20, 2014
Young JY et al: Preoperative imaging of sensorineural hearing loss in pediatric candidates for cochlear implantation. Radiographics. 34(5):E133-49, 2014
Kopelovich JC et al: Early prediction of postmeningitic hearing loss in children using magnetic resonance imaging. Arch Otolaryngol Head Neck Surg. 137(5):441-7, 2011
Durisin M et al: Cochlear osteoneogenesis after meningitis in cochlear implant patients: a retrospective analysis. Otol Neurotol. 31(7):1072-8, 2010
Philippon D et al: Cochlear implantation in postmeningitic deafness. Otol Neurotol. 31(1):83-7, 2010
Saito N et al: Clinical and radiologic manifestations of sickle cell disease in the head and neck. Radiographics. 30(4):1021-34, 2010
Isaacson B et al: Labyrinthitis ossificans: how accurate is MRI in predicting cochlear obstruction? Otolaryngol Head Neck Surg. 140(5):692-6, 2009
Liu BP et al: Labyrinthitis ossificans in a child with sickle cell disease: CT and MRI findings. Pediatr Radiol. 39(9):999-1001, 2009
Ozgen B et al: Complete labyrinthine aplasia: clinical and radiologic findings with review of the literature. AJNR Am J Neuroradiol. 30(4):774-80, 2009
Berrettini S et al: Scala vestibuli cochlear implantation in patients with partially ossified cochleas. J Laryngol Otol. 116(11):946-50, 2002
Glastonbury CM et al: Imaging findings of cochlear nerve deficiency. AJNR Am J Neuroradiol. 23(4):635-43, 2002
Thomas J et al: Evaluation of cochlear implantation in post-meningitic adults. J Laryngol Otol Suppl. 24:27-33, 1999
Muren C et al: Postmeningitic labyrinthine ossification primarily affecting the semicircular canals. Eur Radiol. 7(2):208-13, 1997
Johnson MH et al: CT of postmeningitic deafness: observations and predictive value of cochlear implants in children. AJNR. 16(1):103-9, 1995
Silberman B et al: Role of modern imaging technology in the implementation of pediatric cochlear implants. Ann Otol Rhinol Laryngol. 104(1):42-6, 1995
deSouza C et al: Pathology of labyrinthine ossification. J Laryngol Otol. 105(8):621-4, 1991
Novak MA et al: Labyrinthine ossification after meningitis: its implications for cochlear implantation. Otolaryngol Head Neck Surg. 103(3):351-6, 1990
Steenerson RL et al: Scala vestibuli cochlear implantation for labyrinthine ossification. Am J Otol. 11(5):360-3, 1990
Harnsberger HR et al: Cochlear implant candidates: assessment with CT and MR imaging. Radiology. 164(1):53-7, 1987
Kotzias SA et al: Labyrinthine ossification: differences between two types of ectopic bone. Am J Otol. 6(6):490-4, 1985
Swartz JD et al: Labyrinthine ossification: etiologies and CT findings. Radiology. 157(2):395-8, 1985
Becker TS et al: Labyrinthine ossification secondary to childhood bacterial meningitis: implications for cochlear implant surgery. AJNR Am J Neuroradiol. 5(6):739-41, 1984
Ibrahim RA et al: Labyrinthine ossificans and cochlear implants. Arch Otolaryngol. 106(2):111-3, 1980
Hoffman RA et al: Radiologic diagnosis of labyrinthitis ossificans. Ann Otol Rhinol Laryngol. 88(2 Pt 1):253-7, 1979
Suga F et al: Labyrinthitis ossificans. Ann Otol Rhinol Laryngol. 86(1 Pt 1):17-29, 1977
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