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Lacrimal Gland Benign Mixed Tumor
Daniel E. Meltzer, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Benign mixed tumor (BMT) of lacrimal gland
            • Synonyms

              • Pleomorphic adenoma of lacrimal gland
            • Definitions

              • Benign epithelial neoplasm of lacrimal gland

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. von Holstein SL et al: Tumors of the lacrimal gland. Semin Diagn Pathol. 33(3):156-63, 2016
                                          2. Kim YJ et al: Cytoplasmic and nuclear leptin expression in lacrimal gland tumours: a pilot study. Br J Ophthalmol. ePub, 2015
                                          3. Eldesouky MA et al: Lacrimal fossa lesions: a review of 146 cases in Egypt. Clin Ophthalmol. 8:1603-9, 2014
                                          4. Rootman J et al: Changes in the 7th edition of the AJCC TNM classification and recommendations for pathologic analysis of lacrimal gland tumors. Arch Pathol Lab Med. 133(8):1268-71, 2009
                                          5. Weis E et al: Epithelial lacrimal gland tumors: pathologic classification and current understanding. Arch Ophthalmol. 127(8):1016-28, 2009
                                          6. Bernardini FP et al: Epithelial tumors of the lacrimal gland: an update. Curr Opin Ophthalmol. 19(5):409-13, 2008
                                          7. Vaidhyanath R et al: Lacrimal fossa lesions: pictorial review of CT and MRI features. Orbit. 27(6):410-8, 2008
                                          8. Currie ZI et al: Long-term risk of recurrence after intact excision of pleomorphic adenomas of the lacrimal gland. Arch Ophthalmol. 125(12):1643-6, 2007
                                          9. Porter N et al: Pleomorphic adenoma of the palpebral lobe of the lacrimal gland. Otolaryngol Head Neck Surg. 136(2):328-9, 2007
                                          10. Ramlee N et al: Pleomorphic adenoma in the palpebral lobe of the lacrimal gland misdiagnosed as chalazion. Orbit. 26(2):137-9, 2007
                                          11. Vagefi MR et al: Atypical presentations of pleomorphic adenoma of the lacrimal gland. Ophthal Plast Reconstr Surg. 23(4):272-4, 2007
                                          12. Perez DE et al: Epithelial lacrimal gland tumors: a clinicopathological study of 18 cases. Otolaryngol Head Neck Surg. 134(2):321-5, 2006
                                          13. Marshall AF et al: Pleomorphic adenoma in the palpebral lobe of the lacrimal gland. Otolaryngol Head Neck Surg. 132(1):141-3, 2005
                                          14. Wharton JA et al: Unusual presentations of pleomorphic adenoma and adenoid cystic carcinoma of the lacrimal gland. Aust N Z J Ophthalmol. 27(2):145-8, 1999
                                          15. Rose GE et al: Pleomorphic adenoma of the lacrimal gland. Br J Ophthalmol. 76(7):395-400, 1992
                                          16. Font RL et al: Correlation of computed tomographic and histopathologic features in malignant transformation of benign mixed tumor of lacrimal gland. Surv Ophthalmol. 34(6):449-52, 1990
                                          17. Auran J et al: Benign mixed tumor of the palpebral lobe of the lacrimal gland. Clinical diagnosis and appropriate surgical management. Ophthalmology. 95(1):90-9, 1988
                                          18. Font RL et al: Malignant epithelial tumors of the lacrimal gland. Arch Ophthalmology. 116(5):613-16, 1988
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Benign mixed tumor (BMT) of lacrimal gland
                                                    • Synonyms

                                                      • Pleomorphic adenoma of lacrimal gland
                                                    • Definitions

                                                      • Benign epithelial neoplasm of lacrimal gland

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • Staging, Grading, & Classification

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. von Holstein SL et al: Tumors of the lacrimal gland. Semin Diagn Pathol. 33(3):156-63, 2016
                                                                                  2. Kim YJ et al: Cytoplasmic and nuclear leptin expression in lacrimal gland tumours: a pilot study. Br J Ophthalmol. ePub, 2015
                                                                                  3. Eldesouky MA et al: Lacrimal fossa lesions: a review of 146 cases in Egypt. Clin Ophthalmol. 8:1603-9, 2014
                                                                                  4. Rootman J et al: Changes in the 7th edition of the AJCC TNM classification and recommendations for pathologic analysis of lacrimal gland tumors. Arch Pathol Lab Med. 133(8):1268-71, 2009
                                                                                  5. Weis E et al: Epithelial lacrimal gland tumors: pathologic classification and current understanding. Arch Ophthalmol. 127(8):1016-28, 2009
                                                                                  6. Bernardini FP et al: Epithelial tumors of the lacrimal gland: an update. Curr Opin Ophthalmol. 19(5):409-13, 2008
                                                                                  7. Vaidhyanath R et al: Lacrimal fossa lesions: pictorial review of CT and MRI features. Orbit. 27(6):410-8, 2008
                                                                                  8. Currie ZI et al: Long-term risk of recurrence after intact excision of pleomorphic adenomas of the lacrimal gland. Arch Ophthalmol. 125(12):1643-6, 2007
                                                                                  9. Porter N et al: Pleomorphic adenoma of the palpebral lobe of the lacrimal gland. Otolaryngol Head Neck Surg. 136(2):328-9, 2007
                                                                                  10. Ramlee N et al: Pleomorphic adenoma in the palpebral lobe of the lacrimal gland misdiagnosed as chalazion. Orbit. 26(2):137-9, 2007
                                                                                  11. Vagefi MR et al: Atypical presentations of pleomorphic adenoma of the lacrimal gland. Ophthal Plast Reconstr Surg. 23(4):272-4, 2007
                                                                                  12. Perez DE et al: Epithelial lacrimal gland tumors: a clinicopathological study of 18 cases. Otolaryngol Head Neck Surg. 134(2):321-5, 2006
                                                                                  13. Marshall AF et al: Pleomorphic adenoma in the palpebral lobe of the lacrimal gland. Otolaryngol Head Neck Surg. 132(1):141-3, 2005
                                                                                  14. Wharton JA et al: Unusual presentations of pleomorphic adenoma and adenoid cystic carcinoma of the lacrimal gland. Aust N Z J Ophthalmol. 27(2):145-8, 1999
                                                                                  15. Rose GE et al: Pleomorphic adenoma of the lacrimal gland. Br J Ophthalmol. 76(7):395-400, 1992
                                                                                  16. Font RL et al: Correlation of computed tomographic and histopathologic features in malignant transformation of benign mixed tumor of lacrimal gland. Surv Ophthalmol. 34(6):449-52, 1990
                                                                                  17. Auran J et al: Benign mixed tumor of the palpebral lobe of the lacrimal gland. Clinical diagnosis and appropriate surgical management. Ophthalmology. 95(1):90-9, 1988
                                                                                  18. Font RL et al: Malignant epithelial tumors of the lacrimal gland. Arch Ophthalmology. 116(5):613-16, 1988