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Lacrimal Gland Carcinoma
Daniel E. Meltzer, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Subtypes include adenoid cystic carcinoma (ACCa), adenocarcinoma, squamous cell carcinoma, acinic cell carcinoma, carcinoma ex pleomorphic adenoma
            • Definitions

              • Malignant epithelial neoplasm of lacrimal gland

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • Staging, Grading, & Classification

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Sanders JC et al: Adenoid cystic carcinoma of the lacrimal gland. Am J Otolaryngol. 37(2):144-7, 2016
                                      2. von Holstein SL et al: Tumors of the lacrimal gland. Semin Diagn Pathol. 33(3):156-63, 2016
                                      3. Ahmad SM et al: American Joint Committee on Cancer classification predicts outcome of patients with lacrimal gland adenoid cystic carcinoma. Ophthalmology. 116(6):1210-5, 2009
                                      4. Rootman J et al: Changes in the 7th edition of the AJCC TNM classification and recommendations for pathologic analysis of lacrimal gland tumors. Arch Pathol Lab Med. 133(8):1268-71, 2009
                                      5. Snaathorst J et al: Primary epithelial tumors of the lacrimal gland; a retrospective analysis of 22 patients. Int J Oral Maxillofac Surg. 38(7):751-7, 2009
                                      6. Weis E et al: Epithelial lacrimal gland tumors: pathologic classification and current understanding. Arch Ophthalmol. 127(8):1016-28, 2009
                                      7. Bernardini FP et al: Epithelial tumors of the lacrimal gland: an update. Curr Opin Ophthalmol. 19(5):409-13, 2008
                                      8. Vaidhyanath R et al: Lacrimal fossa lesions: pictorial review of CT and MRI features. Orbit. 27(6):410-8, 2008
                                      9. Jung WS et al: The radiological spectrum of orbital pathologies that involve the lacrimal gland and the lacrimal fossa. Korean J Radiol. 8(4):336-42, 2007
                                      10. Perez DE et al: Epithelial lacrimal gland tumors: a clinicopathological study of 18 cases. Otolaryngol Head Neck Surg. 134(2):321-5, 2006
                                      11. Tse DT et al: Clinical analysis of the effect of intraarterial cytoreductive chemotherapy in the treatment of lacrimal gland adenoid cystic carcinoma. Am J Ophthalmol. 141(1):44-53, 2006
                                      12. Kokemueller H et al: Adenoid cystic carcinoma of the head and neck--a 20 years experience. Int J Oral Maxillofac Surg. 33(1):25-31, 2004
                                      13. Khan AJ et al: Adenoid cystic carcinoma: a retrospective clinical review. Int J Cancer. 96(3):149-58, 2001
                                      14. Balchunas WR et al: Lacrimal gland and fossa masses: evaluation by computed tomography and A-mode echography. Radiology. 149(3):751-8, 1983
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Pathology

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Synonyms

                                                  • Subtypes include adenoid cystic carcinoma (ACCa), adenocarcinoma, squamous cell carcinoma, acinic cell carcinoma, carcinoma ex pleomorphic adenoma
                                                • Definitions

                                                  • Malignant epithelial neoplasm of lacrimal gland

                                                IMAGING

                                                • General Features

                                                  • CT Findings

                                                    • MR Findings

                                                      • Nuclear Medicine Findings

                                                        • Imaging Recommendations

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • Staging, Grading, & Classification

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      DIAGNOSTIC CHECKLIST

                                                                      • Consider

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Sanders JC et al: Adenoid cystic carcinoma of the lacrimal gland. Am J Otolaryngol. 37(2):144-7, 2016
                                                                          2. von Holstein SL et al: Tumors of the lacrimal gland. Semin Diagn Pathol. 33(3):156-63, 2016
                                                                          3. Ahmad SM et al: American Joint Committee on Cancer classification predicts outcome of patients with lacrimal gland adenoid cystic carcinoma. Ophthalmology. 116(6):1210-5, 2009
                                                                          4. Rootman J et al: Changes in the 7th edition of the AJCC TNM classification and recommendations for pathologic analysis of lacrimal gland tumors. Arch Pathol Lab Med. 133(8):1268-71, 2009
                                                                          5. Snaathorst J et al: Primary epithelial tumors of the lacrimal gland; a retrospective analysis of 22 patients. Int J Oral Maxillofac Surg. 38(7):751-7, 2009
                                                                          6. Weis E et al: Epithelial lacrimal gland tumors: pathologic classification and current understanding. Arch Ophthalmol. 127(8):1016-28, 2009
                                                                          7. Bernardini FP et al: Epithelial tumors of the lacrimal gland: an update. Curr Opin Ophthalmol. 19(5):409-13, 2008
                                                                          8. Vaidhyanath R et al: Lacrimal fossa lesions: pictorial review of CT and MRI features. Orbit. 27(6):410-8, 2008
                                                                          9. Jung WS et al: The radiological spectrum of orbital pathologies that involve the lacrimal gland and the lacrimal fossa. Korean J Radiol. 8(4):336-42, 2007
                                                                          10. Perez DE et al: Epithelial lacrimal gland tumors: a clinicopathological study of 18 cases. Otolaryngol Head Neck Surg. 134(2):321-5, 2006
                                                                          11. Tse DT et al: Clinical analysis of the effect of intraarterial cytoreductive chemotherapy in the treatment of lacrimal gland adenoid cystic carcinoma. Am J Ophthalmol. 141(1):44-53, 2006
                                                                          12. Kokemueller H et al: Adenoid cystic carcinoma of the head and neck--a 20 years experience. Int J Oral Maxillofac Surg. 33(1):25-31, 2004
                                                                          13. Khan AJ et al: Adenoid cystic carcinoma: a retrospective clinical review. Int J Cancer. 96(3):149-58, 2001
                                                                          14. Balchunas WR et al: Lacrimal gland and fossa masses: evaluation by computed tomography and A-mode echography. Radiology. 149(3):751-8, 1983