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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Large cell lung carcinoma (LCLC)
Synonyms
- Anaplastic carcinoma
Definitions
- Diagnosis of exclusion
- No features of small cell lung carcinoma or other non-small cell lung carcinomas (NSCLCs) (adenocarcinoma or squamous cell carcinoma)
- Least common type of NSCLC
- Most common subtype: Large cell neuroendocrine carcinoma
- Characteristics common to neuroendocrine tumors and LCLC
- Diagnosis of exclusion
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Pelosi G et al: Large cell carcinoma of the lung: A tumor in search of an author. A clinically oriented critical reappraisal. Lung Cancer. ePub, 2015
- Gollard R et al: Large cell/neuroendocrine carcinoma. Lung Cancer. 69(1):13-8, 2010
- Chong S et al: Neuroendocrine tumors of the lung: clinical, pathologic, and imaging findings. Radiographics. 26(1):41-57; discussion 57-8, 2006
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Large cell lung carcinoma (LCLC)
Synonyms
- Anaplastic carcinoma
Definitions
- Diagnosis of exclusion
- No features of small cell lung carcinoma or other non-small cell lung carcinomas (NSCLCs) (adenocarcinoma or squamous cell carcinoma)
- Least common type of NSCLC
- Most common subtype: Large cell neuroendocrine carcinoma
- Characteristics common to neuroendocrine tumors and LCLC
- Diagnosis of exclusion
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Pelosi G et al: Large cell carcinoma of the lung: A tumor in search of an author. A clinically oriented critical reappraisal. Lung Cancer. ePub, 2015
- Gollard R et al: Large cell/neuroendocrine carcinoma. Lung Cancer. 69(1):13-8, 2010
- Chong S et al: Neuroendocrine tumors of the lung: clinical, pathologic, and imaging findings. Radiographics. 26(1):41-57; discussion 57-8, 2006
