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Large Vessel Vasculitis
James Patrick Davidson, MD; Paige Bennett, MD
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KEY FACTS

  • Terminology

    • Top Differential Diagnoses

      • Clinical Issues

        TERMINOLOGY

        • Definitions

          • Large vessel vasculitis: Inflammation of aorta and major branch vessels
            • Giant cell arteritis
              • Predominately affects White population
              • Common cause of temporal arteritis
            • Takayasu arteritis
              • More common in Asian or Indian patients, women of childbearing age

        IMAGING

        • Imaging Recommendations

          • Correlative Imaging Features

            DIFFERENTIAL DIAGNOSIS

              PATHOLOGY

              • General Features

                CLINICAL ISSUES

                • Presentation

                  • Demographics

                    • Natural History & Prognosis

                      • Treatment

                        DIAGNOSTIC CHECKLIST

                        • Consider

                          Selected References

                          1. Pelletier-Galarneau M et al: PET/CT for diagnosis and management of large-vessel vasculitis. Curr Cardiol Rep. 21(5):34, 2019
                          2. Slart RHJA et al: FDG-PET/CT(A) imaging in large vessel vasculitis and polymyalgia rheumatica: joint procedural recommendation of the EANM, SNMMI, and the PET Interest Group (PIG), and endorsed by the ASNC. Eur J Nucl Med Mol Imaging. 45(7):1250-69, 2018
                          3. Bucerius J: Monitoring vasculitis with 18F-FDG PET. Q J Nucl Med Mol Imaging. 60(3):219-35, 2016
                          4. Soussan M et al: Management of large-vessel vasculitis with FDG-PET: a systematic literature review and meta-analysis. Medicine (Baltimore). 94(14):e622, 2015
                          5. Fuchs M et al: The impact of 18F-FDG PET on the management of patients with suspected large vessel vasculitis. Eur J Nucl Med Mol Imaging. 39(2):344-53, 2012
                          6. James OG et al: Utility of FDG PET/CT in inflammatory cardiovascular disease. Radiographics. 31(5):1271-86, 2011
                          Related Anatomy
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                          Related Differential Diagnoses
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                          References
                          Tables

                          Tables

                          KEY FACTS

                          • Terminology

                            • Top Differential Diagnoses

                              • Clinical Issues

                                TERMINOLOGY

                                • Definitions

                                  • Large vessel vasculitis: Inflammation of aorta and major branch vessels
                                    • Giant cell arteritis
                                      • Predominately affects White population
                                      • Common cause of temporal arteritis
                                    • Takayasu arteritis
                                      • More common in Asian or Indian patients, women of childbearing age

                                IMAGING

                                • Imaging Recommendations

                                  • Correlative Imaging Features

                                    DIFFERENTIAL DIAGNOSIS

                                      PATHOLOGY

                                      • General Features

                                        CLINICAL ISSUES

                                        • Presentation

                                          • Demographics

                                            • Natural History & Prognosis

                                              • Treatment

                                                DIAGNOSTIC CHECKLIST

                                                • Consider

                                                  Selected References

                                                  1. Pelletier-Galarneau M et al: PET/CT for diagnosis and management of large-vessel vasculitis. Curr Cardiol Rep. 21(5):34, 2019
                                                  2. Slart RHJA et al: FDG-PET/CT(A) imaging in large vessel vasculitis and polymyalgia rheumatica: joint procedural recommendation of the EANM, SNMMI, and the PET Interest Group (PIG), and endorsed by the ASNC. Eur J Nucl Med Mol Imaging. 45(7):1250-69, 2018
                                                  3. Bucerius J: Monitoring vasculitis with 18F-FDG PET. Q J Nucl Med Mol Imaging. 60(3):219-35, 2016
                                                  4. Soussan M et al: Management of large-vessel vasculitis with FDG-PET: a systematic literature review and meta-analysis. Medicine (Baltimore). 94(14):e622, 2015
                                                  5. Fuchs M et al: The impact of 18F-FDG PET on the management of patients with suspected large vessel vasculitis. Eur J Nucl Med Mol Imaging. 39(2):344-53, 2012
                                                  6. James OG et al: Utility of FDG PET/CT in inflammatory cardiovascular disease. Radiographics. 31(5):1271-86, 2011