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Laryngeal Chondrosarcoma
Yoshimi Anzai, MD, MPH
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Chondrosarcoma (CSa)
              • Definitions

                • Laryngeal CSa: Cartilage-producing chondrocytic neoplasm with cellular atypia, bone destruction, or local invasion

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              • Reporting Tips

                                                Selected References

                                                1. Bathala S et al: Chondrosarcoma of larynx: review of literature and clinical experience. J Laryngol Otol. 122(10):1127-9, 2008
                                                2. Becker M et al: Imaging of the larynx and hypopharynx. Eur J Radiol. 66(3):460-79, 2008
                                                3. Leclerc JE: Chondrosarcoma of the larynx: case report with a 14-year follow-up. J Otolaryngol Head Neck Surg. 37(5):E143-7, 2008
                                                4. Sauter A et al: Chondrosarcoma of the larynx and review of the literature. Anticancer Res. 27(4C):2925-9, 2007
                                                5. Baatenburg de Jong RJ et al: Chondroma and chondrosarcoma of the larynx. Curr Opin Otolaryngol Head Neck Surg. 12(2):98-105, 2004
                                                6. Rinaggio J et al: Dedifferentiated chondrosarcoma of the larynx. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 97(3):369-75, 2004
                                                7. Shah RK et al: Pathology quiz case 2. Laryngeal chondrosarcoma. Arch Otolaryngol Head Neck Surg. 130(3):367, 369-70, 2004
                                                8. Cohen JT et al: Hemicricoidectomy as the primary diagnosis and treatment for cricoid chondrosarcomas. Laryngoscope. 113(10):1817-9, 2003
                                                9. Jones DA et al: Cartilaginous tumours of the larynx. J Otolaryngol. 32(5):332-7, 2003
                                                10. Orlandi A et al: Symptomatic laryngeal nodular chondrometaplasia: a clinicopathological study. J Clin Pathol. 56(12):976-7, 2003
                                                11. Windfuhr JP: Pitfalls in the diagnosis and management of laryngeal chondrosarcoma. J Laryngol Otol. 117(8):651-5, 2003
                                                12. Dailiana T et al: Chondrosarcoma of the larynx: treatment with radiotherapy. Skeletal Radiol. 31(9):547-9, 2002
                                                13. Garcia RE et al: Dedifferentiated chondrosarcomas of the larynx: a report of two cases and review of the literature. Laryngoscope. 112(6):1015-8, 2002
                                                14. Palacios E et al: Chondrosarcoma of the larynx. Ear Nose Throat J. 81(2):83, 2002
                                                15. Schwab B et al: [The monthly interesting case--Case No. 54. Chondrosarcoma of the larynx] Laryngorhinootologie. 81(8):591-3, 2002
                                                16. Thompson LD et al: Chondrosarcoma of the larynx: a clinicopathologic study of 111 cases with a review of the literature. Am J Surg Pathol. 26(7):836-51, 2002
                                                17. Shinhar S et al: Chondrosarcoma of the larynx: a therapeutic challenge. Ear Nose Throat J. 80(8):568-70, 572, 574, 2001
                                                18. Thome R et al: Long-term follow-up of cartilaginous tumors of the larynx. Otolaryngol Head Neck Surg. 124(6):634-40, 2001
                                                19. Uygur K et al: Chondrosarcoma of the thyroid cartilage. J Laryngol Otol. 115(6):507-9, 2001
                                                20. Friedlander PL et al: Chondrosarcoma of the larynx. Otolaryngol Head Neck Surg. 122(4):617, 2000
                                                21. Rinaldo A et al: Laryngeal chondrosarcoma: a 24-year experience at the Royal National Throat, Nose and Ear Hospital. Acta Otolaryngol. 120(6):680-8, 2000
                                                22. Wang SJ et al: Chondroid tumors of the larynx: computed tomography findings. Am J Otolaryngol. 20(6):379-82, 1999
                                                23. Kozelsky TF et al: Laryngeal chondrosarcomas: the Mayo Clinic experience. J Surg Oncol. 65(4):269-73, 1997
                                                24. Lewis JE et al: Cartilaginous tumors of the larynx: clinicopathologic review of 47 cases. Ann Otol Rhinol Laryngol. 106(2):94-100, 1997
                                                25. Wippold FJ 2nd et al: Chondrosarcoma of the larynx: CT features. AJNR Am J Neuroradiol. 14(2):453-9, 1993
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Pathology

                                                        • Clinical Issues

                                                          • Diagnostic Checklist

                                                            TERMINOLOGY

                                                            • Abbreviations

                                                              • Chondrosarcoma (CSa)
                                                            • Definitions

                                                              • Laryngeal CSa: Cartilage-producing chondrocytic neoplasm with cellular atypia, bone destruction, or local invasion

                                                            IMAGING

                                                            • General Features

                                                              • Radiographic Findings

                                                                • CT Findings

                                                                  • MR Findings

                                                                    • Imaging Recommendations

                                                                      DIFFERENTIAL DIAGNOSIS

                                                                        PATHOLOGY

                                                                        • General Features

                                                                          • Staging, Grading, & Classification

                                                                            • Gross Pathologic & Surgical Features

                                                                              • Microscopic Features

                                                                                CLINICAL ISSUES

                                                                                • Presentation

                                                                                  • Demographics

                                                                                    • Natural History & Prognosis

                                                                                      • Treatment

                                                                                        DIAGNOSTIC CHECKLIST

                                                                                        • Consider

                                                                                          • Image Interpretation Pearls

                                                                                            • Reporting Tips

                                                                                              Selected References

                                                                                              1. Bathala S et al: Chondrosarcoma of larynx: review of literature and clinical experience. J Laryngol Otol. 122(10):1127-9, 2008
                                                                                              2. Becker M et al: Imaging of the larynx and hypopharynx. Eur J Radiol. 66(3):460-79, 2008
                                                                                              3. Leclerc JE: Chondrosarcoma of the larynx: case report with a 14-year follow-up. J Otolaryngol Head Neck Surg. 37(5):E143-7, 2008
                                                                                              4. Sauter A et al: Chondrosarcoma of the larynx and review of the literature. Anticancer Res. 27(4C):2925-9, 2007
                                                                                              5. Baatenburg de Jong RJ et al: Chondroma and chondrosarcoma of the larynx. Curr Opin Otolaryngol Head Neck Surg. 12(2):98-105, 2004
                                                                                              6. Rinaggio J et al: Dedifferentiated chondrosarcoma of the larynx. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 97(3):369-75, 2004
                                                                                              7. Shah RK et al: Pathology quiz case 2. Laryngeal chondrosarcoma. Arch Otolaryngol Head Neck Surg. 130(3):367, 369-70, 2004
                                                                                              8. Cohen JT et al: Hemicricoidectomy as the primary diagnosis and treatment for cricoid chondrosarcomas. Laryngoscope. 113(10):1817-9, 2003
                                                                                              9. Jones DA et al: Cartilaginous tumours of the larynx. J Otolaryngol. 32(5):332-7, 2003
                                                                                              10. Orlandi A et al: Symptomatic laryngeal nodular chondrometaplasia: a clinicopathological study. J Clin Pathol. 56(12):976-7, 2003
                                                                                              11. Windfuhr JP: Pitfalls in the diagnosis and management of laryngeal chondrosarcoma. J Laryngol Otol. 117(8):651-5, 2003
                                                                                              12. Dailiana T et al: Chondrosarcoma of the larynx: treatment with radiotherapy. Skeletal Radiol. 31(9):547-9, 2002
                                                                                              13. Garcia RE et al: Dedifferentiated chondrosarcomas of the larynx: a report of two cases and review of the literature. Laryngoscope. 112(6):1015-8, 2002
                                                                                              14. Palacios E et al: Chondrosarcoma of the larynx. Ear Nose Throat J. 81(2):83, 2002
                                                                                              15. Schwab B et al: [The monthly interesting case--Case No. 54. Chondrosarcoma of the larynx] Laryngorhinootologie. 81(8):591-3, 2002
                                                                                              16. Thompson LD et al: Chondrosarcoma of the larynx: a clinicopathologic study of 111 cases with a review of the literature. Am J Surg Pathol. 26(7):836-51, 2002
                                                                                              17. Shinhar S et al: Chondrosarcoma of the larynx: a therapeutic challenge. Ear Nose Throat J. 80(8):568-70, 572, 574, 2001
                                                                                              18. Thome R et al: Long-term follow-up of cartilaginous tumors of the larynx. Otolaryngol Head Neck Surg. 124(6):634-40, 2001
                                                                                              19. Uygur K et al: Chondrosarcoma of the thyroid cartilage. J Laryngol Otol. 115(6):507-9, 2001
                                                                                              20. Friedlander PL et al: Chondrosarcoma of the larynx. Otolaryngol Head Neck Surg. 122(4):617, 2000
                                                                                              21. Rinaldo A et al: Laryngeal chondrosarcoma: a 24-year experience at the Royal National Throat, Nose and Ear Hospital. Acta Otolaryngol. 120(6):680-8, 2000
                                                                                              22. Wang SJ et al: Chondroid tumors of the larynx: computed tomography findings. Am J Otolaryngol. 20(6):379-82, 1999
                                                                                              23. Kozelsky TF et al: Laryngeal chondrosarcomas: the Mayo Clinic experience. J Surg Oncol. 65(4):269-73, 1997
                                                                                              24. Lewis JE et al: Cartilaginous tumors of the larynx: clinicopathologic review of 47 cases. Ann Otol Rhinol Laryngol. 106(2):94-100, 1997
                                                                                              25. Wippold FJ 2nd et al: Chondrosarcoma of the larynx: CT features. AJNR Am J Neuroradiol. 14(2):453-9, 1993