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Laryngocele
H. Ric Harnsberger, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Internal laryngocele = simple laryngocele
              • Mixed (combined, external) laryngocele: Laryngocele with extralaryngeal extension
              • Saccular cyst: Currently, term best reserved for congenital laryngocele
            • Definitions

              • Laryngeal saccule: Normal mucosal outpouching projecting superiorly from laryngeal ventricle
                • Contains numerous mucous glands
                • Some think saccule's function is lubrication of true cords
              • Internal laryngocele: Dilated, air- or fluid-filled laryngeal saccule
                • Located in paraglottic space of supraglottis
                • Synonym: Simple laryngocele
              • Mixed laryngocele: Extends from paraglottic space through thyrohyoid membrane to low submandibular space (SMS)
                • Synonym: Mixed laryngocele
                • Contains internal (intralaryngeal) & external (extralaryngeal) components
              • Pyolaryngocele: Pus-containing superinfected laryngocele
              • Secondary laryngocele: Glottic or inferior supraglottic SCCa obstructs laryngeal ventricle
                • 15% of all laryngoceles

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          • Reporting Tips

                                            Selected References

                                            1. Zelenik K et al: Treatment of Laryngoceles: what is the progress over the last two decades? Biomed Res Int. 2014:819453, 2014
                                            2. Töro K et al: Fatal asphyxia due to laryngomucocele. Forensic Sci Int. 190(1-3):e1-4, 2009
                                            3. Dursun G et al: Current diagnosis and treatment of laryngocele in adults. Otolaryngol Head Neck Surg. 136(2):211-5, 2007
                                            4. Schmidt M et al: False-positive uptake of I-131 in a laryngocele mimicking thyroid remnant after thyroidectomy for papillary thyroid carcinoma. Clin Nucl Med. 31(11):716-7, 2006
                                            5. Akbas Y et al: Asymptomatic bilateral mixed-type laryngocele and laryngeal carcinoma. Eur Arch Otorhinolaryngol. 261(6):307-9, 2004
                                            6. Ling FT et al: Is there a role for conservative management for symptomatic laryngopyocele? Case report and literature review. J Otolaryngol. 33(4):264-8, 2004
                                            7. Ettema SL et al: Laryngocele resection by combined external and endoscopic laser approach. Ann Otol Rhinol Laryngol. 112(4):361-4, 2003
                                            8. Stocker DJ et al: Bilateral external laryngoceles following radioiodine ablation for Graves disease. Arch Intern Med. 162(17):2007-9, 2002
                                            9. Harney M et al: Laryngocele and squamous cell carcinoma of the larynx. J Laryngol Otol. 115(7):590-2, 2001
                                            10. Thabet MH et al: Lateral saccular cysts of the larynx. Aetiology, diagnosis and management. J Laryngol Otol. 115(4):293-7, 2001
                                            11. Cassano L et al: Laryngopyocele: three new clinical cases and review of the literature. Eur Arch Otorhinolaryngol. 257(9):507-11, 2000
                                            12. Nazaroglu H et al: Laryngopyocele: signs on computed tomography. Eur J Radiol. 33(1):63-5, 2000
                                            13. Aydin O et al: Laryngeal amyloidosis with laryngocele. J Laryngol Otol. 113(4):361-3, 1999
                                            14. Alvi A et al: Computed tomographic and magnetic resonance imaging characteristics of laryngocele and its variants. Am J Otolaryngol. 19(4):251-6, 1998
                                            15. Arslan A et al: Laryngeal amyloidosis with laryngocele: MRI and CT. Neuroradiology. 40(6):401-3, 1998
                                            16. Celin SE et al: The association of laryngoceles with squamous cell carcinoma of the larynx. Laryngoscope. 101(5):529-36, 1991
                                            17. Lewis CA et al: Symptomatic external laryngocele in a newborn: findings on plain radiographs and CT scans. AJNR Am J Neuroradiol. 11(5):1002, 1990
                                            18. Swartz JD et al: The laryngeal mucocele. Imaging analysis of a rare lesion. Clin Imaging. 14(2):110-5, 1990
                                            19. Glazer HS et al: Computed tomography of laryngoceles. AJR Am J Roentgenol. 140(3):549-52, 1983
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Synonyms

                                                        • Internal laryngocele = simple laryngocele
                                                        • Mixed (combined, external) laryngocele: Laryngocele with extralaryngeal extension
                                                        • Saccular cyst: Currently, term best reserved for congenital laryngocele
                                                      • Definitions

                                                        • Laryngeal saccule: Normal mucosal outpouching projecting superiorly from laryngeal ventricle
                                                          • Contains numerous mucous glands
                                                          • Some think saccule's function is lubrication of true cords
                                                        • Internal laryngocele: Dilated, air- or fluid-filled laryngeal saccule
                                                          • Located in paraglottic space of supraglottis
                                                          • Synonym: Simple laryngocele
                                                        • Mixed laryngocele: Extends from paraglottic space through thyrohyoid membrane to low submandibular space (SMS)
                                                          • Synonym: Mixed laryngocele
                                                          • Contains internal (intralaryngeal) & external (extralaryngeal) components
                                                        • Pyolaryngocele: Pus-containing superinfected laryngocele
                                                        • Secondary laryngocele: Glottic or inferior supraglottic SCCa obstructs laryngeal ventricle
                                                          • 15% of all laryngoceles

                                                      IMAGING

                                                      • General Features

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • MR Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  • Image Interpretation Pearls

                                                                                    • Reporting Tips

                                                                                      Selected References

                                                                                      1. Zelenik K et al: Treatment of Laryngoceles: what is the progress over the last two decades? Biomed Res Int. 2014:819453, 2014
                                                                                      2. Töro K et al: Fatal asphyxia due to laryngomucocele. Forensic Sci Int. 190(1-3):e1-4, 2009
                                                                                      3. Dursun G et al: Current diagnosis and treatment of laryngocele in adults. Otolaryngol Head Neck Surg. 136(2):211-5, 2007
                                                                                      4. Schmidt M et al: False-positive uptake of I-131 in a laryngocele mimicking thyroid remnant after thyroidectomy for papillary thyroid carcinoma. Clin Nucl Med. 31(11):716-7, 2006
                                                                                      5. Akbas Y et al: Asymptomatic bilateral mixed-type laryngocele and laryngeal carcinoma. Eur Arch Otorhinolaryngol. 261(6):307-9, 2004
                                                                                      6. Ling FT et al: Is there a role for conservative management for symptomatic laryngopyocele? Case report and literature review. J Otolaryngol. 33(4):264-8, 2004
                                                                                      7. Ettema SL et al: Laryngocele resection by combined external and endoscopic laser approach. Ann Otol Rhinol Laryngol. 112(4):361-4, 2003
                                                                                      8. Stocker DJ et al: Bilateral external laryngoceles following radioiodine ablation for Graves disease. Arch Intern Med. 162(17):2007-9, 2002
                                                                                      9. Harney M et al: Laryngocele and squamous cell carcinoma of the larynx. J Laryngol Otol. 115(7):590-2, 2001
                                                                                      10. Thabet MH et al: Lateral saccular cysts of the larynx. Aetiology, diagnosis and management. J Laryngol Otol. 115(4):293-7, 2001
                                                                                      11. Cassano L et al: Laryngopyocele: three new clinical cases and review of the literature. Eur Arch Otorhinolaryngol. 257(9):507-11, 2000
                                                                                      12. Nazaroglu H et al: Laryngopyocele: signs on computed tomography. Eur J Radiol. 33(1):63-5, 2000
                                                                                      13. Aydin O et al: Laryngeal amyloidosis with laryngocele. J Laryngol Otol. 113(4):361-3, 1999
                                                                                      14. Alvi A et al: Computed tomographic and magnetic resonance imaging characteristics of laryngocele and its variants. Am J Otolaryngol. 19(4):251-6, 1998
                                                                                      15. Arslan A et al: Laryngeal amyloidosis with laryngocele: MRI and CT. Neuroradiology. 40(6):401-3, 1998
                                                                                      16. Celin SE et al: The association of laryngoceles with squamous cell carcinoma of the larynx. Laryngoscope. 101(5):529-36, 1991
                                                                                      17. Lewis CA et al: Symptomatic external laryngocele in a newborn: findings on plain radiographs and CT scans. AJNR Am J Neuroradiol. 11(5):1002, 1990
                                                                                      18. Swartz JD et al: The laryngeal mucocele. Imaging analysis of a rare lesion. Clin Imaging. 14(2):110-5, 1990
                                                                                      19. Glazer HS et al: Computed tomography of laryngoceles. AJR Am J Roentgenol. 140(3):549-52, 1983