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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Legg-Calvé-Perthes (LCP) disease
Synonyms
- Legg-Perthes or Perthes disease
- Juvenile idiopathic osteonecrosis
Definitions
- Idiopathic osteonecrosis of femoral head in children
IMAGING
General Features
Radiographic Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Chong DY et al: Reliability and validity of visual estimation of femoral head hypoperfusion on perfusion MRI in Legg-Calve-Perthes disease. J Pediatr Orthop. 41(9):e780-6, 2021
- Jones CE et al: T1ρ and T2 MRI show hip cartilage damage in adolescents with healed Legg-Calvé-Perthes disease. J Pediatr Orthop B. ePub, 2021
- Tis JE et al: Reproducibility of radiographic measurements made in the active stages of Legg-Calvé-Perthes disease: evaluation of a prognostic indicator and an interim outcome measure. J Pediatr Orthop. 41(2):93-8, 2021
- Pavone V et al: Aetiology of Legg-Calvé-Perthes disease: a systematic review. World J Orthop. 10(3):145-65, 2019
- Jandl NM et al: MRI and sonography in Legg-Calvé-Perthes disease: clinical relevance of containment and influence on treatment. J Child Orthop. 12(5):472-9, 2018
- Divi SN et al: Legg-Calvé-Perthes disease. Pediatr Ann. 45(4):e144-9, 2016
- Yoo WJ et al: Risk factors for femoral head deformity in the early stage of Legg-Calvé-Perthes disease: MR contrast enhancement and diffusion indexes. Radiology. 279(2):562-70, 2016
- Heesakkers N et al: The long-term prognosis of Legg-Calvé-Perthes disease: a historical prospective study with a median follow-up of forty one years. Int Orthop. 39(5):859-63, 2015
- Hyman JE et al: Interobserver and intraobserver reliability of the modified Waldenström classification system for staging of Legg-Calvé-Perthes disease. J Bone Joint Surg Am. 97(8):643-50, 2015
- Kotoura Y et al: Assessment of lateral subluxation in Legg-Calvé-Perthes disease: a time-sequential study of magnetic resonance imaging and plain radiography. J Pediatr Orthop B. 24(6):493-506, 2015
- Accadbled F et al: "Femoroacetabular impingement". Legg-Calve-Perthes disease: from childhood to adulthood. Orthop Traumatol Surg Res. 100(6):647-9, 2014
- Kim HK et al: Perfusion MRI in early stage of Legg-Calvé-Perthes disease to predict lateral pillar involvement: a preliminary study. J Bone Joint Surg Am. 96(14):1152-60, 2014
- Mazloumi SM et al: Evolution in diagnosis and treatment of Legg-Calve-Perthes disease. Arch Bone Jt Surg. 2(2):86-92, 2014
- Park KW et al: Extent of physeal involvement in Legg-Calvé-Perthes disease. Int Orthop. 38(11):2303-8, 2014
- Shah H: Perthes disease: Evaluation and management. Orthop Clin North Am. 45(1):87-97, 2014
- Kim HK et al: A comparison of non-contrast and contrast-enhanced MRI in the initial stage of Legg-Calvé-Perthes disease. Pediatr Radiol. 43(9):1166-73, 2013
- Shah H et al: Quantitative measures for evaluating the radiographic outcome of Legg-Calvé-Perthes disease. J Bone Joint Surg Am. 95(4):354-61, 2013
- Nguyen NA et al: Operative versus nonoperative treatments for Legg-Calvé-Perthes disease: a meta-analysis. J Pediatr Orthop. 32(7):697-705, 2012
- Park MS et al: Reliability and stability of three common classifications for Legg-Calvé-Perthes disease. Clin Orthop Relat Res. 470(9):2376-82, 2012
- Ross JR et al: Intraarticular abnormalities in residual Perthes and Perthes-like hip deformities. Clin Orthop Relat Res. 470(11):2968-77, 2012
- Kuo KN et al: Classification of Legg-Calvé-Perthes disease. J Pediatr Orthop. 31(2 Suppl):S168-73, 2011
- Lobert PF et al: Unexpected MRI findings in clinically suspected Legg-Calvé-Perthes disease. Pediatr Radiol. 41(3):369-73, 2011
- Merlini L et al: Diffusion-weighted imaging findings in Perthes disease with dynamic gadolinium-enhanced subtracted (DGS) MR correlation: a preliminary study. Pediatr Radiol. 40(3):318-25, 2010
- Zilkens C et al: Delayed gadolinium-enhanced magnetic resonance imaging of cartilage in the long-term follow-up after Perthes disease. J Pediatr Orthop. 30(2):147-53, 2010
- Dillman JR et al: MRI of Legg-Calve-Perthes disease. AJR Am J Roentgenol. 193(5):1394-407, 2009
- Ha AS et al: Importance of sagittal MR imaging in nontraumatic femoral head osteonecrosis in children. Pediatr Radiol. 38(11):1195-200, 2008
- Link TM et al: Cartilage imaging: motivation, techniques, current and future significance. Eur Radiol. 17(5):1135-46, 2007
- Van Tongel A et al: Epiphysiodesis of the greater trochanter in Legg-Calvé-Perthes disease: the importance of timing. Acta Orthop Belg. 72(3):309-13, 2006
- Rowe SM et al: Dysplasia epiphysealis capitis femoris: Meyer dysplasia. J Pediatr Orthop. 25(1):18-21, 2005
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Legg-Calvé-Perthes (LCP) disease
Synonyms
- Legg-Perthes or Perthes disease
- Juvenile idiopathic osteonecrosis
Definitions
- Idiopathic osteonecrosis of femoral head in children
IMAGING
General Features
Radiographic Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Chong DY et al: Reliability and validity of visual estimation of femoral head hypoperfusion on perfusion MRI in Legg-Calve-Perthes disease. J Pediatr Orthop. 41(9):e780-6, 2021
- Jones CE et al: T1ρ and T2 MRI show hip cartilage damage in adolescents with healed Legg-Calvé-Perthes disease. J Pediatr Orthop B. ePub, 2021
- Tis JE et al: Reproducibility of radiographic measurements made in the active stages of Legg-Calvé-Perthes disease: evaluation of a prognostic indicator and an interim outcome measure. J Pediatr Orthop. 41(2):93-8, 2021
- Pavone V et al: Aetiology of Legg-Calvé-Perthes disease: a systematic review. World J Orthop. 10(3):145-65, 2019
- Jandl NM et al: MRI and sonography in Legg-Calvé-Perthes disease: clinical relevance of containment and influence on treatment. J Child Orthop. 12(5):472-9, 2018
- Divi SN et al: Legg-Calvé-Perthes disease. Pediatr Ann. 45(4):e144-9, 2016
- Yoo WJ et al: Risk factors for femoral head deformity in the early stage of Legg-Calvé-Perthes disease: MR contrast enhancement and diffusion indexes. Radiology. 279(2):562-70, 2016
- Heesakkers N et al: The long-term prognosis of Legg-Calvé-Perthes disease: a historical prospective study with a median follow-up of forty one years. Int Orthop. 39(5):859-63, 2015
- Hyman JE et al: Interobserver and intraobserver reliability of the modified Waldenström classification system for staging of Legg-Calvé-Perthes disease. J Bone Joint Surg Am. 97(8):643-50, 2015
- Kotoura Y et al: Assessment of lateral subluxation in Legg-Calvé-Perthes disease: a time-sequential study of magnetic resonance imaging and plain radiography. J Pediatr Orthop B. 24(6):493-506, 2015
- Accadbled F et al: "Femoroacetabular impingement". Legg-Calve-Perthes disease: from childhood to adulthood. Orthop Traumatol Surg Res. 100(6):647-9, 2014
- Kim HK et al: Perfusion MRI in early stage of Legg-Calvé-Perthes disease to predict lateral pillar involvement: a preliminary study. J Bone Joint Surg Am. 96(14):1152-60, 2014
- Mazloumi SM et al: Evolution in diagnosis and treatment of Legg-Calve-Perthes disease. Arch Bone Jt Surg. 2(2):86-92, 2014
- Park KW et al: Extent of physeal involvement in Legg-Calvé-Perthes disease. Int Orthop. 38(11):2303-8, 2014
- Shah H: Perthes disease: Evaluation and management. Orthop Clin North Am. 45(1):87-97, 2014
- Kim HK et al: A comparison of non-contrast and contrast-enhanced MRI in the initial stage of Legg-Calvé-Perthes disease. Pediatr Radiol. 43(9):1166-73, 2013
- Shah H et al: Quantitative measures for evaluating the radiographic outcome of Legg-Calvé-Perthes disease. J Bone Joint Surg Am. 95(4):354-61, 2013
- Nguyen NA et al: Operative versus nonoperative treatments for Legg-Calvé-Perthes disease: a meta-analysis. J Pediatr Orthop. 32(7):697-705, 2012
- Park MS et al: Reliability and stability of three common classifications for Legg-Calvé-Perthes disease. Clin Orthop Relat Res. 470(9):2376-82, 2012
- Ross JR et al: Intraarticular abnormalities in residual Perthes and Perthes-like hip deformities. Clin Orthop Relat Res. 470(11):2968-77, 2012
- Kuo KN et al: Classification of Legg-Calvé-Perthes disease. J Pediatr Orthop. 31(2 Suppl):S168-73, 2011
- Lobert PF et al: Unexpected MRI findings in clinically suspected Legg-Calvé-Perthes disease. Pediatr Radiol. 41(3):369-73, 2011
- Merlini L et al: Diffusion-weighted imaging findings in Perthes disease with dynamic gadolinium-enhanced subtracted (DGS) MR correlation: a preliminary study. Pediatr Radiol. 40(3):318-25, 2010
- Zilkens C et al: Delayed gadolinium-enhanced magnetic resonance imaging of cartilage in the long-term follow-up after Perthes disease. J Pediatr Orthop. 30(2):147-53, 2010
- Dillman JR et al: MRI of Legg-Calve-Perthes disease. AJR Am J Roentgenol. 193(5):1394-407, 2009
- Ha AS et al: Importance of sagittal MR imaging in nontraumatic femoral head osteonecrosis in children. Pediatr Radiol. 38(11):1195-200, 2008
- Link TM et al: Cartilage imaging: motivation, techniques, current and future significance. Eur Radiol. 17(5):1135-46, 2007
- Van Tongel A et al: Epiphysiodesis of the greater trochanter in Legg-Calvé-Perthes disease: the importance of timing. Acta Orthop Belg. 72(3):309-13, 2006
- Rowe SM et al: Dysplasia epiphysealis capitis femoris: Meyer dysplasia. J Pediatr Orthop. 25(1):18-21, 2005
