Benign smooth muscle tumor that occurs in skin, subcutaneous tissues, or deep soft tissues
Clinical groups
(1) Cutaneous leiomyoma (leiomyoma cutis)
Includes genital leiomyomas and piloleiomyomas
(2) Angioleiomyomas (angiomyoma or vascular leiomyoma)
Typically subcutaneous
From tunica media of vein
(3) Leiomyoma of deep soft tissues
Deep soft tissues of extremity or retroperitoneum (females)
Much less common than superficial types
Can be confused with leiomyosarcoma, which is more common
IMAGING
General Features
Ultrasonographic Findings
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Demographics
Natural History & Prognosis
Treatment
Selected References
Marcoval J et al: Cutaneous leiomyoma: a clinical study of 152 patients. Dermatology. 1-7, 2021
Billings SD et al: Leiomyoma. In Fletcher CDM et al: WHO Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 188-9, 2020
McCarthy AJ et al: Benign smooth muscle tumors (leiomyomas) of deep somatic soft tissue. Sarcoma. 2018:2071394, 2018
Arleo EK et al: Review of leiomyoma variants. AJR Am J Roentgenol. 205(4):912-21, 2015
Kransdorf MJ et al: Muscle tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 361-7, 2014
Fasih N et al: Leiomyomas beyond the uterus: unusual locations, rare manifestations. Radiographics. 28(7):1931-48, 2008
Weiss SW et al: Benign tumors of smooth muscle. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 522-8, 2008
Hashimoto H et al: Leiomyoma of deep soft tissue. In Fletcher CDM et al: WHO Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 130, 2002
Related Anatomy
Loading...
Related Differential Diagnoses
Loading...
References
Tables
Tables
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Definitions
Benign smooth muscle tumor that occurs in skin, subcutaneous tissues, or deep soft tissues
Clinical groups
(1) Cutaneous leiomyoma (leiomyoma cutis)
Includes genital leiomyomas and piloleiomyomas
(2) Angioleiomyomas (angiomyoma or vascular leiomyoma)
Typically subcutaneous
From tunica media of vein
(3) Leiomyoma of deep soft tissues
Deep soft tissues of extremity or retroperitoneum (females)
Much less common than superficial types
Can be confused with leiomyosarcoma, which is more common
IMAGING
General Features
Ultrasonographic Findings
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Demographics
Natural History & Prognosis
Treatment
Selected References
Marcoval J et al: Cutaneous leiomyoma: a clinical study of 152 patients. Dermatology. 1-7, 2021
Billings SD et al: Leiomyoma. In Fletcher CDM et al: WHO Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 188-9, 2020
McCarthy AJ et al: Benign smooth muscle tumors (leiomyomas) of deep somatic soft tissue. Sarcoma. 2018:2071394, 2018
Arleo EK et al: Review of leiomyoma variants. AJR Am J Roentgenol. 205(4):912-21, 2015
Kransdorf MJ et al: Muscle tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 361-7, 2014
Fasih N et al: Leiomyomas beyond the uterus: unusual locations, rare manifestations. Radiographics. 28(7):1931-48, 2008
Weiss SW et al: Benign tumors of smooth muscle. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 522-8, 2008
Hashimoto H et al: Leiomyoma of deep soft tissue. In Fletcher CDM et al: WHO Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 130, 2002
STATdx includes over 200,000 searchable images, including x-ray, CT, MR, and ultrasound images. To access all images, please log in or subscribe.