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Leiomyosarcoma
Catherine C. Roberts, MD; B.J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Definitions

            • Malignant neoplasm arising from smooth muscle cells

          IMAGING

          • General Features

            • Imaging Recommendations

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Angiographic Findings

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          Selected References

                                          1. Gordon RW et al: MRI, MDCT features, and clinical outcome of extremity leiomyosarcomas: experience in 47 patients. Skeletal Radiol. 43(5):615-22, 2014
                                          2. Weiss SW et al: Leiomyosarcoma. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier. 545-64, 2008
                                          3. Efstathopoulos N et al: Inflammatory leiomyosarcoma of the ankle: a case report and review of the literature. J Foot Ankle Surg. 45(2):127-30, 2006
                                          4. Kransdorf MJ et al: Muscle tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 306-12, 2006
                                          5. Massi D et al: Prognostic factors in soft tissue leiomyosarcoma of the extremities: a retrospective analysis of 42 cases. Eur J Surg Oncol. 30(5):565-72, 2004
                                          6. Evans HL et al: Leiomyosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 131-4, 2002
                                          7. Abdelwahab IF et al: Radiation-induced leiomyosarcoma. Skeletal Radiol. 24(1):81-3, 1995
                                          8. Kransdorf MJ: Malignant soft-tissue tumors in a large referral population: distribution of diagnoses by age, sex, and location. AJR Am J Roentgenol. 164(1):129-34, 1995
                                          9. Hartman DS et al: From the archives of the AFIP. Leiomyosarcoma of the retroperitoneum and inferior vena cava: radiologic-pathologic correlation. Radiographics. 12(6):1203-20, 1992
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Definitions

                                                    • Malignant neoplasm arising from smooth muscle cells

                                                  IMAGING

                                                  • General Features

                                                    • Imaging Recommendations

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • MR Findings

                                                            • Ultrasonographic Findings

                                                              • Angiographic Findings

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  Selected References

                                                                                  1. Gordon RW et al: MRI, MDCT features, and clinical outcome of extremity leiomyosarcomas: experience in 47 patients. Skeletal Radiol. 43(5):615-22, 2014
                                                                                  2. Weiss SW et al: Leiomyosarcoma. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier. 545-64, 2008
                                                                                  3. Efstathopoulos N et al: Inflammatory leiomyosarcoma of the ankle: a case report and review of the literature. J Foot Ankle Surg. 45(2):127-30, 2006
                                                                                  4. Kransdorf MJ et al: Muscle tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 306-12, 2006
                                                                                  5. Massi D et al: Prognostic factors in soft tissue leiomyosarcoma of the extremities: a retrospective analysis of 42 cases. Eur J Surg Oncol. 30(5):565-72, 2004
                                                                                  6. Evans HL et al: Leiomyosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 131-4, 2002
                                                                                  7. Abdelwahab IF et al: Radiation-induced leiomyosarcoma. Skeletal Radiol. 24(1):81-3, 1995
                                                                                  8. Kransdorf MJ: Malignant soft-tissue tumors in a large referral population: distribution of diagnoses by age, sex, and location. AJR Am J Roentgenol. 164(1):129-34, 1995
                                                                                  9. Hartman DS et al: From the archives of the AFIP. Leiomyosarcoma of the retroperitoneum and inferior vena cava: radiologic-pathologic correlation. Radiographics. 12(6):1203-20, 1992