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Lip Squamous Cell Carcinoma
Christine M. Glastonbury, MBBS
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Lip squamous cell carcinoma (SCCa)
              • Definitions

                • Oral cavity malignancy arising from mucosa of lips (vermilion)
                  • Upper lip and lower lip
                    • Vermilion is term for reddish lip skin
                  • Vermilion border is term for where lip meets facial skin
                  • Vermilion meets buccal mucosa at inner aspect of lip

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            • Reporting Tips

                                              Selected References

                                              1. Luna-Ortiz K et al: Upper lip malignant neoplasms. A study of 59 cases. Med Oral Patol Oral Cir Bucal. Epub ahead of print, 2011
                                              2. López-Pintor RM et al: Lip cancer in renal transplant patients. Oral Oncol. 47(1):68-71, 2011
                                              3. Samarasinghe V et al: Management of high-risk squamous cell carcinoma of the skin. Expert Rev Anticancer Ther. 11(5):763-9, 2011
                                              4. Souza RL et al: Lip squamous cell carcinoma in a Brazilian population: epidemiological study and clinicopathological associations. Med Oral Patol Oral Cir Bucal. 16(6):e757-62, 2011
                                              5. Casal D et al: Lip cancer: a 5-year review in a tertiary referral centre. J Plast Reconstr Aesthet Surg. 63(12):2040-5, 2010
                                              6. Czerninski R et al: Lip cancer: incidence, trends, histology and survival: 1970-2006. Br J Dermatol. 162(5):1103-9, 2010
                                              7. Hamadah I et al: Squamous cell carcinoma of the lip after allogeneic hemopoietic stem cell transplantation. Hematol Oncol Stem Cell Ther. 3(2):84-8, 2010
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        • Diagnostic Checklist

                                                          TERMINOLOGY

                                                          • Abbreviations

                                                            • Lip squamous cell carcinoma (SCCa)
                                                          • Definitions

                                                            • Oral cavity malignancy arising from mucosa of lips (vermilion)
                                                              • Upper lip and lower lip
                                                                • Vermilion is term for reddish lip skin
                                                              • Vermilion border is term for where lip meets facial skin
                                                              • Vermilion meets buccal mucosa at inner aspect of lip

                                                          IMAGING

                                                          • General Features

                                                            • CT Findings

                                                              • MR Findings

                                                                • Nuclear Medicine Findings

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Staging, Grading, & Classification

                                                                          • Gross Pathologic & Surgical Features

                                                                            CLINICAL ISSUES

                                                                            • Presentation

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Consider

                                                                                      • Image Interpretation Pearls

                                                                                        • Reporting Tips

                                                                                          Selected References

                                                                                          1. Luna-Ortiz K et al: Upper lip malignant neoplasms. A study of 59 cases. Med Oral Patol Oral Cir Bucal. Epub ahead of print, 2011
                                                                                          2. López-Pintor RM et al: Lip cancer in renal transplant patients. Oral Oncol. 47(1):68-71, 2011
                                                                                          3. Samarasinghe V et al: Management of high-risk squamous cell carcinoma of the skin. Expert Rev Anticancer Ther. 11(5):763-9, 2011
                                                                                          4. Souza RL et al: Lip squamous cell carcinoma in a Brazilian population: epidemiological study and clinicopathological associations. Med Oral Patol Oral Cir Bucal. 16(6):e757-62, 2011
                                                                                          5. Casal D et al: Lip cancer: a 5-year review in a tertiary referral centre. J Plast Reconstr Aesthet Surg. 63(12):2040-5, 2010
                                                                                          6. Czerninski R et al: Lip cancer: incidence, trends, histology and survival: 1970-2006. Br J Dermatol. 162(5):1103-9, 2010
                                                                                          7. Hamadah I et al: Squamous cell carcinoma of the lip after allogeneic hemopoietic stem cell transplantation. Hematol Oncol Stem Cell Ther. 3(2):84-8, 2010