link
Bookmarks
Lipoblastoma/Lipoblastomatosis
Eric Walker, MD, MHA, FACR, FACHE; Catherine C. Roberts, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Subscribe
0
3
3
0

KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Benign lipoblastoma, diffuse lipoblastomatosis, fetal lipoma, embryonic lipoma, infantile lipoma, fetal fat tumor, fetocellular lipoma, congenital lipomatoid tumor, lipoblastic tumor of childhood
            • Definitions

              • Circumscribed (lipoblastoma) and diffuse (lipoblastomatosis) forms of benign pediatric tumor composed of immature fat cells
              • Lipoblastomatosis originates in deep soft tissues and is more infiltrative

            IMAGING

            • General Features

              • Radiographic Findings

                • MR Findings

                  • CT Findings

                    • Ultrasonographic Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              • Reporting Tips

                                                Selected References

                                                1. Black JO et al: Lipoblastoma and lipoblastomatosis. In Fletcher CDM et al: WHO Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 20-2, 2020
                                                2. Séguier-Lipszyc E et al: Current management of lipoblastoma. European Journal of Pediatrics. (177)237–41, 2018
                                                3. Abdul-Ghafar J et al: Lipoblastoma: a clinicopathologic review of 23 cases from a major tertiary care center plus detailed review of literature. BMC Res Notes. 11(1):42, 2018
                                                4. Dadone B et al: Molecular cytogenetics of pediatric adipocytic tumors. Cancer Genet. 208(10):469-81, 2015
                                                5. Kransdorf MJ et al: Lipomatous Tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 131-5; 2014
                                                6. Salem R et al: Lipoblastoma: a rare lesion in the differential diagnosis of childhood mediastinal tumors. J Pediatr Surg. 46(5):e21-3, 2011
                                                7. Weiss SW et al: Benign lipomatous tumors. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 452-5, 2008
                                                Related Anatomy
                                                Loading...
                                                Related Differential Diagnoses
                                                Loading...
                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Pathology

                                                      • Clinical Issues

                                                        • Diagnostic Checklist

                                                          TERMINOLOGY

                                                          • Synonyms

                                                            • Benign lipoblastoma, diffuse lipoblastomatosis, fetal lipoma, embryonic lipoma, infantile lipoma, fetal fat tumor, fetocellular lipoma, congenital lipomatoid tumor, lipoblastic tumor of childhood
                                                          • Definitions

                                                            • Circumscribed (lipoblastoma) and diffuse (lipoblastomatosis) forms of benign pediatric tumor composed of immature fat cells
                                                            • Lipoblastomatosis originates in deep soft tissues and is more infiltrative

                                                          IMAGING

                                                          • General Features

                                                            • Radiographic Findings

                                                              • MR Findings

                                                                • CT Findings

                                                                  • Ultrasonographic Findings

                                                                    • Imaging Recommendations

                                                                      DIFFERENTIAL DIAGNOSIS

                                                                        PATHOLOGY

                                                                        • General Features

                                                                          • Staging, Grading, & Classification

                                                                            • Gross Pathologic & Surgical Features

                                                                              • Microscopic Features

                                                                                CLINICAL ISSUES

                                                                                • Presentation

                                                                                  • Demographics

                                                                                    • Natural History & Prognosis

                                                                                      • Treatment

                                                                                        DIAGNOSTIC CHECKLIST

                                                                                        • Consider

                                                                                          • Image Interpretation Pearls

                                                                                            • Reporting Tips

                                                                                              Selected References

                                                                                              1. Black JO et al: Lipoblastoma and lipoblastomatosis. In Fletcher CDM et al: WHO Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 20-2, 2020
                                                                                              2. Séguier-Lipszyc E et al: Current management of lipoblastoma. European Journal of Pediatrics. (177)237–41, 2018
                                                                                              3. Abdul-Ghafar J et al: Lipoblastoma: a clinicopathologic review of 23 cases from a major tertiary care center plus detailed review of literature. BMC Res Notes. 11(1):42, 2018
                                                                                              4. Dadone B et al: Molecular cytogenetics of pediatric adipocytic tumors. Cancer Genet. 208(10):469-81, 2015
                                                                                              5. Kransdorf MJ et al: Lipomatous Tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 131-5; 2014
                                                                                              6. Salem R et al: Lipoblastoma: a rare lesion in the differential diagnosis of childhood mediastinal tumors. J Pediatr Surg. 46(5):e21-3, 2011
                                                                                              7. Weiss SW et al: Benign lipomatous tumors. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 452-5, 2008