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Breast
Histopathologic Diagnoses
Benign Lesions
Lipoma and Angiolipoma
Lipoma and Angiolipoma
Wendie A. Berg, MD, PhD, FACR, FSBI; Wei Tse Yang, MBBS
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Definitions

                • Lipoma: Benign neoplasm composed of mature adipose cells
                • Angiolipoma: Benign fatty neoplasm with capillary networks and fibrin thrombi

              IMAGING

              • General Features

                • Mammographic Findings

                  • Ultrasonographic Findings

                    • MR Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Hicks DG et al: Lipoma and angiolipoma. In: Diagnostic Pathology: Breast, 2nd ed. Philadelphia: Elsevier, 2016
                                        2. Bouroumane MR et al: Breast lipoma with central fat necrosis: case report. Pan Afr Med J. 25:235, 2016
                                        3. Spear SL et al: The safety, effectiveness, and efficiency of autologous fat grafting in breast surgery. Plast Reconstr Surg Glob Open. 4(8):e827, 2016
                                        4. Hoda SA et al: Rosen's Breast Pathology, 4th edition. Philadelphia: Lippincott Williams & Wilkins, 2014
                                        5. Kitagawa Y et al: Subcutaneous angiolipoma: magnetic resonance imaging features with histological correlation. J Nippon Med Sch. 81(5):313-9, 2014
                                        6. Lee JH et al: Well-circumscribed type of intramuscular lipoma in the chest wall. J Cardiothorac Surg. 8:181, 2013
                                        7. Weinstein SP et al: Case 59: Angiolipoma of the breast. Radiology. 227(3):773-5, 2013
                                        8. Groh O et al: Giant lipoma of the male breast: case report and review of literature. Eur J Plast Surg. 35(5):407-409, 2012
                                        9. Li YF et al: Giant lipoma of the breast: a case report and review of the literature. Clin Breast Cancer. 11(6):420-2, 2011
                                        10. Schmidt J et al: Giant lipoma of the breast. Breast J. 15(1):107-8, 2009
                                        11. Pant R et al: An unusual case of an intramuscular lipoma of the pectoralis major muscle simulating a malignant breast mass. Ann Acad Med Singapore. 34(3):275-6, 2005
                                        12. Gaskin CM et al: Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses. AJR Am J Roentgenol. 182(3):733-9, 2004
                                        13. Lanng C et al: Lipoma of the breast: a diagnostic dilemma. Breast. 13(5):408-11, 2004
                                        14. Kopans D: Breast Imaging. 2nd ed. Philadelphia: Lippincott-Raven. 551-8, 1998
                                        15. Roberts CC et al: Encapsulated versus nonencapsulated superficial fatty masses: a proposed MR imaging classification. AJR Am J Roentgenol. 180(5):1419-22, 2003
                                        16. Hall FM et al: Lipomatous pseudomass of the breast: diagnosis suggested by discordant palpatory and mammographic findings. Radiology. 164(2):463-4, 1987
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Definitions

                                                      • Lipoma: Benign neoplasm composed of mature adipose cells
                                                      • Angiolipoma: Benign fatty neoplasm with capillary networks and fibrin thrombi

                                                    IMAGING

                                                    • General Features

                                                      • Mammographic Findings

                                                        • Ultrasonographic Findings

                                                          • MR Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • Gross Pathologic & Surgical Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Hicks DG et al: Lipoma and angiolipoma. In: Diagnostic Pathology: Breast, 2nd ed. Philadelphia: Elsevier, 2016
                                                                              2. Bouroumane MR et al: Breast lipoma with central fat necrosis: case report. Pan Afr Med J. 25:235, 2016
                                                                              3. Spear SL et al: The safety, effectiveness, and efficiency of autologous fat grafting in breast surgery. Plast Reconstr Surg Glob Open. 4(8):e827, 2016
                                                                              4. Hoda SA et al: Rosen's Breast Pathology, 4th edition. Philadelphia: Lippincott Williams & Wilkins, 2014
                                                                              5. Kitagawa Y et al: Subcutaneous angiolipoma: magnetic resonance imaging features with histological correlation. J Nippon Med Sch. 81(5):313-9, 2014
                                                                              6. Lee JH et al: Well-circumscribed type of intramuscular lipoma in the chest wall. J Cardiothorac Surg. 8:181, 2013
                                                                              7. Weinstein SP et al: Case 59: Angiolipoma of the breast. Radiology. 227(3):773-5, 2013
                                                                              8. Groh O et al: Giant lipoma of the male breast: case report and review of literature. Eur J Plast Surg. 35(5):407-409, 2012
                                                                              9. Li YF et al: Giant lipoma of the breast: a case report and review of the literature. Clin Breast Cancer. 11(6):420-2, 2011
                                                                              10. Schmidt J et al: Giant lipoma of the breast. Breast J. 15(1):107-8, 2009
                                                                              11. Pant R et al: An unusual case of an intramuscular lipoma of the pectoralis major muscle simulating a malignant breast mass. Ann Acad Med Singapore. 34(3):275-6, 2005
                                                                              12. Gaskin CM et al: Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses. AJR Am J Roentgenol. 182(3):733-9, 2004
                                                                              13. Lanng C et al: Lipoma of the breast: a diagnostic dilemma. Breast. 13(5):408-11, 2004
                                                                              14. Kopans D: Breast Imaging. 2nd ed. Philadelphia: Lippincott-Raven. 551-8, 1998
                                                                              15. Roberts CC et al: Encapsulated versus nonencapsulated superficial fatty masses: a proposed MR imaging classification. AJR Am J Roentgenol. 180(5):1419-22, 2003
                                                                              16. Hall FM et al: Lipomatous pseudomass of the breast: diagnosis suggested by discordant palpatory and mammographic findings. Radiology. 164(2):463-4, 1987