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Lipoma of Head and Neck
Hilda E. Stambuk, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Definitions

              • Benign neoplasm composed of mature fat

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Imaging Recommendations

                      • Nuclear Medicine Findings

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            • Reporting Tips

                                              Selected References

                                              1. de Bree E et al: Lipomatous tumours of the head and neck: a spectrum of biological behaviour. Eur Arch Otorhinolaryngol. 272(5):1061-77, 2015
                                              2. Tadisina KK et al: Syndromic lipomatosis of the head and neck: a review of the literature. Aesthetic Plast Surg. 39(3):440-8, 2015
                                              3. Yoshiyama A et al: D-dimer levels in the differential diagnosis between lipoma and well-differentiated liposarcoma. Anticancer Res. 34(9):5181-5, 2014
                                              4. Choi JW et al: Spindle cell lipoma of the head and neck: CT and MR imaging findings. Neuroradiology. 55(1):101-6, 2013
                                              5. Durr ML et al: Laryngeal lipoma associated with diffuse lipomatosis: case report and literature review. Ear Nose Throat J. 89(1):34-7, 2010
                                              6. Kok KY et al: Lipoblastoma: clinical features, treatment, and outcome. World J Surg. 34(7):1517-22, 2010
                                              7. Mandal RV et al: Infiltrating intramuscular spindle cell lipoma of the face. J Cutan Pathol. 36 Suppl 1:70-3, 2009
                                              8. Cappabianca S et al: Lipomatous lesions of the head and neck region: imaging findings in comparison with histological type. Radiol Med. 113(5):758-70, 2008
                                              9. Dalal KM et al: Diagnosis and management of lipomatous tumors. J Surg Oncol. 97(4):298-313, 2008
                                              10. Eloy JA et al: A rare prevertebral ordinary lipoma presenting as obstructive sleep apnea: computed tomographic and magnetic resonance imaging findings. Arch Otolaryngol Head Neck Surg. 134(9):1001-3, 2008
                                              11. Smith CS et al: False-positive findings on 18F-FDG PET/CT: differentiation of hibernoma and malignant fatty tumor on the basis of fluctuating standardized uptake values. AJR Am J Roentgenol. 190(4):1091-6, 2008
                                              12. Teive HA et al: Cerebellar ataxia, myoclonus, cervical lipomas, and MERRF syndrome. Case report. Mov Disord. 23(8):1191-2, 2008
                                              13. Zhang XY et al: Madelung disease: manifestations of CT and MR imaging. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 105(5):e57-64, 2008
                                              14. Canto C et al: Lipofibroma of the neck in children: an unusual diagnosis with special surgical implications. Otolaryngol Head Neck Surg. 137(6):976-8, 2007
                                              15. Chung JC et al: A huge tongue lipoma. Otolaryngol Head Neck Surg. 137(5):830-1, 2007
                                              16. Hameed M: Pathology and genetics of adipocytic tumors. Cytogenet Genome Res. 118(2-4):138-47, 2007
                                              17. Gong W et al: A retropharyngeal lipoma causing obstructive sleep apnea in a child. J Clin Sleep Med. 2(3):328-9, 2006
                                              18. Kaneyama K et al: Magnetic resonance imaging in lipoblastoma: can it be a diagnostic modality? Asian J Surg. 29(3):198-201, 2006
                                              19. Moholkar S et al: Radiological-pathological correlation in lipoblastoma and lipoblastomatosis. Pediatr Radiol. 36(8):851-6, 2006
                                              20. Bancroft LW et al: Imaging characteristics of spindle cell lipoma. AJR Am J Roentgenol. 181(5):1251-4, 2003
                                              21. Petrow P et al: Normal intratumoral lymph node in a patient with lipoma mimicking liposarcoma. AJR Am J Roentgenol. 181(2):569-70, 2003
                                              22. Salvatore C et al: Giant infiltrating lipoma of the face: CT and MR imaging findings. AJNR Am J Neuroradiol. 24(2):283-6, 2003
                                              23. Gritzmann N et al: Sonography of soft tissue masses of the neck. J Clin Ultrasound. 30(6):356-73, 2002
                                              24. Rubin BP et al: The genetics of lipomatous tumors. Semin Diagn Pathol. 18(4):286-93, 2001
                                              25. Ahuja AT et al: Head and neck lipomas: sonographic appearance. AJNR Am J Neuroradiol. 19(3):505-8, 1998
                                              26. Ahuja AT et al: Madelung disease: distribution of cervical fat and preoperative findings at sonography, MR, and CT. AJNR Am J Neuroradiol. 19(4):707-10, 1998
                                              27. Ha TV et al: MR imaging of benign fatty tumors in children: report of four cases and review of the literature. Skeletal Radiol. 23(5):361-7, 1994
                                              28. Tien RD et al: Improved detection and delineation of head and neck lesions with fat suppression spin-echo MR imaging. AJNR Am J Neuroradiol. 12(1):19-24, 1991
                                              29. Gritzmann N et al: Sonography and computed tomography in deep cervical lipomas and lipomatosis of the neck. J Ultrasound Med. 7(8):451-6, 1988
                                              30. Som PM et al: Rare presentations of ordinary lipomas of the head and neck: a review. AJNR Am J Neuroradiol. 7(4):657-64, 1986
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Definitions

                                                          • Benign neoplasm composed of mature fat

                                                        IMAGING

                                                        • General Features

                                                          • CT Findings

                                                            • MR Findings

                                                              • Ultrasonographic Findings

                                                                • Imaging Recommendations

                                                                  • Nuclear Medicine Findings

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Gross Pathologic & Surgical Features

                                                                          • Microscopic Features

                                                                            CLINICAL ISSUES

                                                                            • Presentation

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Consider

                                                                                      • Image Interpretation Pearls

                                                                                        • Reporting Tips

                                                                                          Selected References

                                                                                          1. de Bree E et al: Lipomatous tumours of the head and neck: a spectrum of biological behaviour. Eur Arch Otorhinolaryngol. 272(5):1061-77, 2015
                                                                                          2. Tadisina KK et al: Syndromic lipomatosis of the head and neck: a review of the literature. Aesthetic Plast Surg. 39(3):440-8, 2015
                                                                                          3. Yoshiyama A et al: D-dimer levels in the differential diagnosis between lipoma and well-differentiated liposarcoma. Anticancer Res. 34(9):5181-5, 2014
                                                                                          4. Choi JW et al: Spindle cell lipoma of the head and neck: CT and MR imaging findings. Neuroradiology. 55(1):101-6, 2013
                                                                                          5. Durr ML et al: Laryngeal lipoma associated with diffuse lipomatosis: case report and literature review. Ear Nose Throat J. 89(1):34-7, 2010
                                                                                          6. Kok KY et al: Lipoblastoma: clinical features, treatment, and outcome. World J Surg. 34(7):1517-22, 2010
                                                                                          7. Mandal RV et al: Infiltrating intramuscular spindle cell lipoma of the face. J Cutan Pathol. 36 Suppl 1:70-3, 2009
                                                                                          8. Cappabianca S et al: Lipomatous lesions of the head and neck region: imaging findings in comparison with histological type. Radiol Med. 113(5):758-70, 2008
                                                                                          9. Dalal KM et al: Diagnosis and management of lipomatous tumors. J Surg Oncol. 97(4):298-313, 2008
                                                                                          10. Eloy JA et al: A rare prevertebral ordinary lipoma presenting as obstructive sleep apnea: computed tomographic and magnetic resonance imaging findings. Arch Otolaryngol Head Neck Surg. 134(9):1001-3, 2008
                                                                                          11. Smith CS et al: False-positive findings on 18F-FDG PET/CT: differentiation of hibernoma and malignant fatty tumor on the basis of fluctuating standardized uptake values. AJR Am J Roentgenol. 190(4):1091-6, 2008
                                                                                          12. Teive HA et al: Cerebellar ataxia, myoclonus, cervical lipomas, and MERRF syndrome. Case report. Mov Disord. 23(8):1191-2, 2008
                                                                                          13. Zhang XY et al: Madelung disease: manifestations of CT and MR imaging. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 105(5):e57-64, 2008
                                                                                          14. Canto C et al: Lipofibroma of the neck in children: an unusual diagnosis with special surgical implications. Otolaryngol Head Neck Surg. 137(6):976-8, 2007
                                                                                          15. Chung JC et al: A huge tongue lipoma. Otolaryngol Head Neck Surg. 137(5):830-1, 2007
                                                                                          16. Hameed M: Pathology and genetics of adipocytic tumors. Cytogenet Genome Res. 118(2-4):138-47, 2007
                                                                                          17. Gong W et al: A retropharyngeal lipoma causing obstructive sleep apnea in a child. J Clin Sleep Med. 2(3):328-9, 2006
                                                                                          18. Kaneyama K et al: Magnetic resonance imaging in lipoblastoma: can it be a diagnostic modality? Asian J Surg. 29(3):198-201, 2006
                                                                                          19. Moholkar S et al: Radiological-pathological correlation in lipoblastoma and lipoblastomatosis. Pediatr Radiol. 36(8):851-6, 2006
                                                                                          20. Bancroft LW et al: Imaging characteristics of spindle cell lipoma. AJR Am J Roentgenol. 181(5):1251-4, 2003
                                                                                          21. Petrow P et al: Normal intratumoral lymph node in a patient with lipoma mimicking liposarcoma. AJR Am J Roentgenol. 181(2):569-70, 2003
                                                                                          22. Salvatore C et al: Giant infiltrating lipoma of the face: CT and MR imaging findings. AJNR Am J Neuroradiol. 24(2):283-6, 2003
                                                                                          23. Gritzmann N et al: Sonography of soft tissue masses of the neck. J Clin Ultrasound. 30(6):356-73, 2002
                                                                                          24. Rubin BP et al: The genetics of lipomatous tumors. Semin Diagn Pathol. 18(4):286-93, 2001
                                                                                          25. Ahuja AT et al: Head and neck lipomas: sonographic appearance. AJNR Am J Neuroradiol. 19(3):505-8, 1998
                                                                                          26. Ahuja AT et al: Madelung disease: distribution of cervical fat and preoperative findings at sonography, MR, and CT. AJNR Am J Neuroradiol. 19(4):707-10, 1998
                                                                                          27. Ha TV et al: MR imaging of benign fatty tumors in children: report of four cases and review of the literature. Skeletal Radiol. 23(5):361-7, 1994
                                                                                          28. Tien RD et al: Improved detection and delineation of head and neck lesions with fat suppression spin-echo MR imaging. AJNR Am J Neuroradiol. 12(1):19-24, 1991
                                                                                          29. Gritzmann N et al: Sonography and computed tomography in deep cervical lipomas and lipomatosis of the neck. J Ultrasound Med. 7(8):451-6, 1988
                                                                                          30. Som PM et al: Rare presentations of ordinary lipomas of the head and neck: a review. AJNR Am J Neuroradiol. 7(4):657-64, 1986