Intradural (juxtamedullary, subpial) or terminal lipoma
Definitions
Spinal lipoma intimately associated with spinal cord (intradural) or distal cord/filum insertion (terminal)
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Pang D: Surgical management of complex spinal cord lipomas: how, why, and when to operate. a review. J Neurosurg Pediatr. 23(5):537-56, 2019
Rhodes RH: Congenital spinal lipomatous malformations. part 1. spinal lipomas, lipomyeloceles, and lipomyelomeningoceles. Fetal Pediatr Pathol. 1-52, 2019
Jones V et al: The pathology of lumbosacral lipomas: macroscopic and microscopic disparity have implications for embryogenesis and mode of clinical deterioration. Histopathology. 72(7):1136-44, 2018
Seki T et al: Surgical outcomes of pediatric patients with asymptomatic tethered cord syndrome. Asian Spine J. 12(3):551-5, 2018
Morioka T et al: Neurosurgical management and pathology of lumbosacral lipomas with tethered cord. Neuropathology. 37(5):385-92, 2017
Morota N et al: New classification of spinal lipomas based on embryonic stage. J Neurosurg Pediatr. 19(4):428-39, 2017
Severino R et al: Cervical intramedullary spinal cord lipoma. Surg Neurol Int. 8:255, 2017
Cools MJ et al: Filum terminale lipomas: imaging prevalence, natural history, and conus position. J Neurosurg Pediatr. 13(5):559-67, 2014
Harada A et al: Intraspinal lesions associated with sacrococcygeal dimples. J Neurosurg Pediatr. 14(1):81-6, 2014
Horrion J et al: Adult intradural lipoma with tethered spinal cord syndrome. JBR-BTR. 97(2):121, 2014
Kole MJ et al: Currarino syndrome and spinal dysraphism. J Neurosurg Pediatr. 13(6):685-9, 2014
Scottoni F et al: Spinal ultrasound in patients with anorectal malformations: is this the end of an era? Pediatr Surg Int. 30(8):829-31, 2014
Borg H et al: Impact of spinal cord malformation on bladder function in children with anorectal malformations. J Pediatr Surg. 44(9):1778-85, 2009
Muthukumar N: Congenital spinal lipomatous malformations: part II--clinical presentation, operative findings, and outcome. Acta Neurochir (Wien). 151(3):189-97; discussion 197, 2009
Oi S et al: Embryopathogenetic surgicoanatomical classification of dysraphism and surgical outcome of spinal lipoma: a nationwide multicenter cooperative study in Japan. J Neurosurg Pediatr. 3(5):412-9, 2009
Pang D et al: Long-term outcome of total and near-total resection of spinal cord lipomas and radical reconstruction of the neural placode: part I-surgical technique. Neurosurgery. 65(3):511-28; discussion 528-9, 2009
Samuels R et al: Incidence of symptomatic retethering after surgical management of pediatric tethered cord syndrome with or without duraplasty. Childs Nerv Syst. 25(9):1085-9, 2009
Koyanagi I et al: Radiological findings and clinical course of conus lipoma: implications for surgical treatment. Neurosurgery. 63(3):546-51; discussion 551-2, 2008
Torre M et al: Long-term urologic outcome in patients with caudal regression syndrome, compared with meningomyelocele and spinal cord lipoma. J Pediatr Surg. 43(3):530-3, 2008
Finn MA et al: Spinal lipomas: clinical spectrum, embryology, and treatment. Neurosurg Focus. 23(2):1-12, 2007
Arai H et al: Surgical experience of 120 patients with lumbosacral lipomas. Acta Neurochir (Wien). 143(9):857-64, 2001
Bulsara KR et al: Clinical outcome differences for lipomyelomeningoceles, intraspinal lipomas, and lipomas of the filum terminale. Neurosurg Rev. 24(4):192-4, 2001
Tortori-Donati P et al: Magnetic resonance imaging of spinal dysraphism. Top Magn Reson Imaging. 12(6):375-409, 2001
van Leeuwen R et al: Surgery in adults with tethered cord syndrome: outcome study with independent clinical review. J Neurosurg. 94(2 Suppl):205-9, 2001
Unsinn KM et al: US of the spinal cord in newborns: spectrum of normal findings, variants, congenital anomalies, and acquired diseases. Radiographics. 20(4):923-38, 2000
Endoh M et al: Spontaneous shrinkage of lumbosacral lipoma in conjunction with a general decrease in body fat: case report. Neurosurgery. 43(1):150-1; discussion 151-2, 1998
Iskandar BJ et al: Congenital tethered spinal cord syndrome in adults. J Neurosurg. 88(6):958-61, 1998
Byrne RW et al: Operative resection of 100 spinal lipomas in infants less than 1 year of age. Pediatr Neurosurg. 23(4):182-6; discussion 186-7, 1995
Fujiwara F et al: Intradural spinal lipomas not associated with spinal dysraphism: a report of four cases. Neurosurgery. 37(6):1212-5, 1995
Aoki N: Rapid growth of intraspinal lipoma demonstrated by magnetic resonance imaging. Surg Neurol. 34(2):107-10, 1990
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
Intradural (juxtamedullary, subpial) or terminal lipoma
Definitions
Spinal lipoma intimately associated with spinal cord (intradural) or distal cord/filum insertion (terminal)
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Pang D: Surgical management of complex spinal cord lipomas: how, why, and when to operate. a review. J Neurosurg Pediatr. 23(5):537-56, 2019
Rhodes RH: Congenital spinal lipomatous malformations. part 1. spinal lipomas, lipomyeloceles, and lipomyelomeningoceles. Fetal Pediatr Pathol. 1-52, 2019
Jones V et al: The pathology of lumbosacral lipomas: macroscopic and microscopic disparity have implications for embryogenesis and mode of clinical deterioration. Histopathology. 72(7):1136-44, 2018
Seki T et al: Surgical outcomes of pediatric patients with asymptomatic tethered cord syndrome. Asian Spine J. 12(3):551-5, 2018
Morioka T et al: Neurosurgical management and pathology of lumbosacral lipomas with tethered cord. Neuropathology. 37(5):385-92, 2017
Morota N et al: New classification of spinal lipomas based on embryonic stage. J Neurosurg Pediatr. 19(4):428-39, 2017
Severino R et al: Cervical intramedullary spinal cord lipoma. Surg Neurol Int. 8:255, 2017
Cools MJ et al: Filum terminale lipomas: imaging prevalence, natural history, and conus position. J Neurosurg Pediatr. 13(5):559-67, 2014
Harada A et al: Intraspinal lesions associated with sacrococcygeal dimples. J Neurosurg Pediatr. 14(1):81-6, 2014
Horrion J et al: Adult intradural lipoma with tethered spinal cord syndrome. JBR-BTR. 97(2):121, 2014
Kole MJ et al: Currarino syndrome and spinal dysraphism. J Neurosurg Pediatr. 13(6):685-9, 2014
Scottoni F et al: Spinal ultrasound in patients with anorectal malformations: is this the end of an era? Pediatr Surg Int. 30(8):829-31, 2014
Borg H et al: Impact of spinal cord malformation on bladder function in children with anorectal malformations. J Pediatr Surg. 44(9):1778-85, 2009
Muthukumar N: Congenital spinal lipomatous malformations: part II--clinical presentation, operative findings, and outcome. Acta Neurochir (Wien). 151(3):189-97; discussion 197, 2009
Oi S et al: Embryopathogenetic surgicoanatomical classification of dysraphism and surgical outcome of spinal lipoma: a nationwide multicenter cooperative study in Japan. J Neurosurg Pediatr. 3(5):412-9, 2009
Pang D et al: Long-term outcome of total and near-total resection of spinal cord lipomas and radical reconstruction of the neural placode: part I-surgical technique. Neurosurgery. 65(3):511-28; discussion 528-9, 2009
Samuels R et al: Incidence of symptomatic retethering after surgical management of pediatric tethered cord syndrome with or without duraplasty. Childs Nerv Syst. 25(9):1085-9, 2009
Koyanagi I et al: Radiological findings and clinical course of conus lipoma: implications for surgical treatment. Neurosurgery. 63(3):546-51; discussion 551-2, 2008
Torre M et al: Long-term urologic outcome in patients with caudal regression syndrome, compared with meningomyelocele and spinal cord lipoma. J Pediatr Surg. 43(3):530-3, 2008
Finn MA et al: Spinal lipomas: clinical spectrum, embryology, and treatment. Neurosurg Focus. 23(2):1-12, 2007
Arai H et al: Surgical experience of 120 patients with lumbosacral lipomas. Acta Neurochir (Wien). 143(9):857-64, 2001
Bulsara KR et al: Clinical outcome differences for lipomyelomeningoceles, intraspinal lipomas, and lipomas of the filum terminale. Neurosurg Rev. 24(4):192-4, 2001
Tortori-Donati P et al: Magnetic resonance imaging of spinal dysraphism. Top Magn Reson Imaging. 12(6):375-409, 2001
van Leeuwen R et al: Surgery in adults with tethered cord syndrome: outcome study with independent clinical review. J Neurosurg. 94(2 Suppl):205-9, 2001
Unsinn KM et al: US of the spinal cord in newborns: spectrum of normal findings, variants, congenital anomalies, and acquired diseases. Radiographics. 20(4):923-38, 2000
Endoh M et al: Spontaneous shrinkage of lumbosacral lipoma in conjunction with a general decrease in body fat: case report. Neurosurgery. 43(1):150-1; discussion 151-2, 1998
Iskandar BJ et al: Congenital tethered spinal cord syndrome in adults. J Neurosurg. 88(6):958-61, 1998
Byrne RW et al: Operative resection of 100 spinal lipomas in infants less than 1 year of age. Pediatr Neurosurg. 23(4):182-6; discussion 186-7, 1995
Fujiwara F et al: Intradural spinal lipomas not associated with spinal dysraphism: a report of four cases. Neurosurgery. 37(6):1212-5, 1995
Aoki N: Rapid growth of intraspinal lipoma demonstrated by magnetic resonance imaging. Surg Neurol. 34(2):107-10, 1990
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