link
Bookmarks
Lipomatosis of Nerve
Eric Walker, MD, MHA, FACR, FACHE; Catherine C. Roberts, MD
To access 4,300 diagnoses written by the world's leading experts in radiology.Try it free - 15 days
0
4
3
0

KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Neural fibrolipoma, fibrolipomatous hamartoma of nerve, lipofibromatous hamartoma of nerve, neurolipomatosis, lipofibroma, perineural lipoma, fatty infiltration of nerve, intraneural lipoma, interfibrillar lipoma of nerve
          • Definitions

            • Fibrofatty nerve infiltration resulting in fusiform enlargement
          • Associated Syndromes

            • Macrodystrophia lipomatosa in 27-67%

          IMAGING

          • General Features

            • Imaging Recommendations

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      Selected References

                                      1. Marek T et al: What's known and what's new in adipose lesions of peripheral nerves? Acta Neurochir (Wien). 163(3):835-42, 2021
                                      2. Blackburn PR et al: PIK3CA mutations in lipomatosis of nerve with or without nerve territory overgrowth. Mod Pathol. 33(3):420-30, 2020
                                      3. Xu P et al: Ultrasonographic diagnosis of lipomatosis of nerve: a review of ultrasonographic finding for 8 cases. World Neurosurg. 139:e730-6, 2020
                                      4. Marek T et al: Strengthening the association of lipomatosis of nerve and nerve-territory overgrowth: a systematic review. J Neurosurg. 132(4):1286-94, 2019
                                      5. Kransdorf MJ et al: Lipomatous tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 105-9, 2014
                                      6. Mahan MA et al: Occult radiological effects of lipomatosis of the lumbosacral plexus. Skeletal Radiol. 43(7):963-8, 2014
                                      7. Weiss SW et al: Benign lipomatous tumors. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 460-1, 2008
                                      8. Wong BZ et al: Lipomatosis of the sciatic nerve: typical and atypical MRI features. Skeletal Radiol. 35(3):180-4, 2006
                                      Related Anatomy
                                      Loading...
                                      Related Differential Diagnoses
                                      Loading...
                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Pathology

                                            • Clinical Issues

                                              TERMINOLOGY

                                              • Synonyms

                                                • Neural fibrolipoma, fibrolipomatous hamartoma of nerve, lipofibromatous hamartoma of nerve, neurolipomatosis, lipofibroma, perineural lipoma, fatty infiltration of nerve, intraneural lipoma, interfibrillar lipoma of nerve
                                              • Definitions

                                                • Fibrofatty nerve infiltration resulting in fusiform enlargement
                                              • Associated Syndromes

                                                • Macrodystrophia lipomatosa in 27-67%

                                              IMAGING

                                              • General Features

                                                • Imaging Recommendations

                                                  • Radiographic Findings

                                                    • CT Findings

                                                      • MR Findings

                                                        • Ultrasonographic Findings

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          Selected References

                                                                          1. Marek T et al: What's known and what's new in adipose lesions of peripheral nerves? Acta Neurochir (Wien). 163(3):835-42, 2021
                                                                          2. Blackburn PR et al: PIK3CA mutations in lipomatosis of nerve with or without nerve territory overgrowth. Mod Pathol. 33(3):420-30, 2020
                                                                          3. Xu P et al: Ultrasonographic diagnosis of lipomatosis of nerve: a review of ultrasonographic finding for 8 cases. World Neurosurg. 139:e730-6, 2020
                                                                          4. Marek T et al: Strengthening the association of lipomatosis of nerve and nerve-territory overgrowth: a systematic review. J Neurosurg. 132(4):1286-94, 2019
                                                                          5. Kransdorf MJ et al: Lipomatous tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 105-9, 2014
                                                                          6. Mahan MA et al: Occult radiological effects of lipomatosis of the lumbosacral plexus. Skeletal Radiol. 43(7):963-8, 2014
                                                                          7. Weiss SW et al: Benign lipomatous tumors. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 460-1, 2008
                                                                          8. Wong BZ et al: Lipomatosis of the sciatic nerve: typical and atypical MRI features. Skeletal Radiol. 35(3):180-4, 2006