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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Lipomatous hypertrophy of interatrial septum (LHIS or LHIAS)
Synonyms
Lipomatous hypertrophy of atrial septum
Lipomatous hamartoma
Lipomatous hyperplasia
Massive fatty deposits
Definitions
Nonneoplastic deposition of excessive amounts of fat within interatrial septum
1st described in 1964 by JT Prior
Not true neoplasm
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Echocardiographic Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Coulier B et al: Lipomatous hypertrophy of interatrial septum causing hot spot on 18FDG PET/CT. Diagn Interv Imaging. 100(3):197-8, 2019
Rocha RV et al: Adipose tumors of the heart. J Card Surg. 33(8):432-7, 2018
Motwani M et al: MR imaging of cardiac tumors and masses: a review of methods and clinical applications. Radiology. 268(1):26-43, 2013
Lee SH et al: Visceral obesity of the heart: extensive lipomatous hypertrophy of interatrial septum. J Cardiovasc Ultrasound. 20(3):161-2, 2012
Rigatelli G et al: Anatomo-functional characterization of interatrial septum for catheter-based interventions. Am J Cardiovasc Dis. 1(3):227-35, 2011
Pugliatti P et al: Lipomatous hypertrophy of the interatrial septum. Int J Cardiol. 130(2):294-5, 2008
Tugcu A et al: Lipomatous hypertrophy of the interatrial septum presenting as an obstructive right atrial mass in a patient with exertional dyspnea. J Am Soc Echocardiogr. 20(11):1319.e3-5, 2007
Fan CM et al: Lipomatous hypertrophy of the interatrial septum: increased uptake on FDG PET. AJR Am J Roentgenol. 184(1):339-42, 2005
Kuester LB et al: Lipomatous hypertrophy of the interatrial septum: prevalence and features on fusion 18F fluorodeoxyglucose positron emission tomography/CT. Chest. 128(6):3888-93, 2005
Heyer CM et al: Lipomatous hypertrophy of the interatrial septum: a prospective study of incidence, imaging findings, and clinical symptoms. Chest. 124(6):2068-73, 2003
Iacovoni A et al: [Lipomatous hypertrophy of the interatrial septum: its assessment with TEE, CT and MRI.] G Ital Cardiol. 28(11):1273-7, 1998
Meaney JF et al: CT appearance of lipomatous hypertrophy of the interatrial septum. AJR Am J Roentgenol. 168(4):1081-4, 1997
Burke AP et al: Lipomatous hypertrophy of the atrial septum presenting as a right atrial mass. Am J Surg Pathol. 20(6):678-85, 1996
Shirani J et al: Clinical, electrocardiographic and morphologic features of massive fatty deposits ("lipomatous hypertrophy") in the atrial septum. J Am Coll Cardiol. 22(1):226-38, 1993
Lund JT et al: Cardiac masses: assessment by MR imaging. AJR Am J Roentgenol. 152(3):469-73, 1989
Simons M et al: Lipomatous hypertrophy of the atrial septum: diagnosis by combined echocardiography and computerized tomography. Am J Cardiol. 54(3):465-6, 1984
Prior JT: Lipomatous hypertrophy of cardiac interatrial septum: a lesion resembling hibernoma, lipoblastomatosis and infiltrating lipoma. Arch Pathol. 78:11-5, 1964
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Lipomatous hypertrophy of interatrial septum (LHIS or LHIAS)
Synonyms
Lipomatous hypertrophy of atrial septum
Lipomatous hamartoma
Lipomatous hyperplasia
Massive fatty deposits
Definitions
Nonneoplastic deposition of excessive amounts of fat within interatrial septum
1st described in 1964 by JT Prior
Not true neoplasm
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Echocardiographic Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Coulier B et al: Lipomatous hypertrophy of interatrial septum causing hot spot on 18FDG PET/CT. Diagn Interv Imaging. 100(3):197-8, 2019
Rocha RV et al: Adipose tumors of the heart. J Card Surg. 33(8):432-7, 2018
Motwani M et al: MR imaging of cardiac tumors and masses: a review of methods and clinical applications. Radiology. 268(1):26-43, 2013
Lee SH et al: Visceral obesity of the heart: extensive lipomatous hypertrophy of interatrial septum. J Cardiovasc Ultrasound. 20(3):161-2, 2012
Rigatelli G et al: Anatomo-functional characterization of interatrial septum for catheter-based interventions. Am J Cardiovasc Dis. 1(3):227-35, 2011
Pugliatti P et al: Lipomatous hypertrophy of the interatrial septum. Int J Cardiol. 130(2):294-5, 2008
Tugcu A et al: Lipomatous hypertrophy of the interatrial septum presenting as an obstructive right atrial mass in a patient with exertional dyspnea. J Am Soc Echocardiogr. 20(11):1319.e3-5, 2007
Fan CM et al: Lipomatous hypertrophy of the interatrial septum: increased uptake on FDG PET. AJR Am J Roentgenol. 184(1):339-42, 2005
Kuester LB et al: Lipomatous hypertrophy of the interatrial septum: prevalence and features on fusion 18F fluorodeoxyglucose positron emission tomography/CT. Chest. 128(6):3888-93, 2005
Heyer CM et al: Lipomatous hypertrophy of the interatrial septum: a prospective study of incidence, imaging findings, and clinical symptoms. Chest. 124(6):2068-73, 2003
Iacovoni A et al: [Lipomatous hypertrophy of the interatrial septum: its assessment with TEE, CT and MRI.] G Ital Cardiol. 28(11):1273-7, 1998
Meaney JF et al: CT appearance of lipomatous hypertrophy of the interatrial septum. AJR Am J Roentgenol. 168(4):1081-4, 1997
Burke AP et al: Lipomatous hypertrophy of the atrial septum presenting as a right atrial mass. Am J Surg Pathol. 20(6):678-85, 1996
Shirani J et al: Clinical, electrocardiographic and morphologic features of massive fatty deposits ("lipomatous hypertrophy") in the atrial septum. J Am Coll Cardiol. 22(1):226-38, 1993
Lund JT et al: Cardiac masses: assessment by MR imaging. AJR Am J Roentgenol. 152(3):469-73, 1989
Simons M et al: Lipomatous hypertrophy of the atrial septum: diagnosis by combined echocardiography and computerized tomography. Am J Cardiol. 54(3):465-6, 1984
Prior JT: Lipomatous hypertrophy of cardiac interatrial septum: a lesion resembling hibernoma, lipoblastomatosis and infiltrating lipoma. Arch Pathol. 78:11-5, 1964
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