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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Lipomatous hypertrophy of interatrial septum (LHIS or LHIAS)
Synonyms
- Lipomatous hypertrophy of atrial septum
- Lipomatous hamartoma
- Lipomatous hyperplasia
- Massive fatty deposits
Definitions
- Nonneoplastic deposition of excessive amounts of fat within interatrial septum
- 1st described in 1964 by JT Prior
- Not true neoplasm
- Nonneoplastic deposition of excessive amounts of fat within interatrial septum
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Echocardiographic Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Coulier B et al: Lipomatous hypertrophy of interatrial septum causing hot spot on 18FDG PET/CT. Diagn Interv Imaging. 100(3):197-8, 2019
- Rocha RV et al: Adipose tumors of the heart. J Card Surg. 33(8):432-7, 2018
- Motwani M et al: MR imaging of cardiac tumors and masses: a review of methods and clinical applications. Radiology. 268(1):26-43, 2013
- Lee SH et al: Visceral obesity of the heart: extensive lipomatous hypertrophy of interatrial septum. J Cardiovasc Ultrasound. 20(3):161-2, 2012
- Rigatelli G et al: Anatomo-functional characterization of interatrial septum for catheter-based interventions. Am J Cardiovasc Dis. 1(3):227-35, 2011
- Pugliatti P et al: Lipomatous hypertrophy of the interatrial septum. Int J Cardiol. 130(2):294-5, 2008
- Tugcu A et al: Lipomatous hypertrophy of the interatrial septum presenting as an obstructive right atrial mass in a patient with exertional dyspnea. J Am Soc Echocardiogr. 20(11):1319.e3-5, 2007
- Fan CM et al: Lipomatous hypertrophy of the interatrial septum: increased uptake on FDG PET. AJR Am J Roentgenol. 184(1):339-42, 2005
- Kuester LB et al: Lipomatous hypertrophy of the interatrial septum: prevalence and features on fusion 18F fluorodeoxyglucose positron emission tomography/CT. Chest. 128(6):3888-93, 2005
- Heyer CM et al: Lipomatous hypertrophy of the interatrial septum: a prospective study of incidence, imaging findings, and clinical symptoms. Chest. 124(6):2068-73, 2003
- Iacovoni A et al: [Lipomatous hypertrophy of the interatrial septum: its assessment with TEE, CT and MRI.] G Ital Cardiol. 28(11):1273-7, 1998
- Meaney JF et al: CT appearance of lipomatous hypertrophy of the interatrial septum. AJR Am J Roentgenol. 168(4):1081-4, 1997
- Burke AP et al: Lipomatous hypertrophy of the atrial septum presenting as a right atrial mass. Am J Surg Pathol. 20(6):678-85, 1996
- Shirani J et al: Clinical, electrocardiographic and morphologic features of massive fatty deposits ("lipomatous hypertrophy") in the atrial septum. J Am Coll Cardiol. 22(1):226-38, 1993
- Lund JT et al: Cardiac masses: assessment by MR imaging. AJR Am J Roentgenol. 152(3):469-73, 1989
- Simons M et al: Lipomatous hypertrophy of the atrial septum: diagnosis by combined echocardiography and computerized tomography. Am J Cardiol. 54(3):465-6, 1984
- Prior JT: Lipomatous hypertrophy of cardiac interatrial septum: a lesion resembling hibernoma, lipoblastomatosis and infiltrating lipoma. Arch Pathol. 78:11-5, 1964
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References
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Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Lipomatous hypertrophy of interatrial septum (LHIS or LHIAS)
Synonyms
- Lipomatous hypertrophy of atrial septum
- Lipomatous hamartoma
- Lipomatous hyperplasia
- Massive fatty deposits
Definitions
- Nonneoplastic deposition of excessive amounts of fat within interatrial septum
- 1st described in 1964 by JT Prior
- Not true neoplasm
- Nonneoplastic deposition of excessive amounts of fat within interatrial septum
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Echocardiographic Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Coulier B et al: Lipomatous hypertrophy of interatrial septum causing hot spot on 18FDG PET/CT. Diagn Interv Imaging. 100(3):197-8, 2019
- Rocha RV et al: Adipose tumors of the heart. J Card Surg. 33(8):432-7, 2018
- Motwani M et al: MR imaging of cardiac tumors and masses: a review of methods and clinical applications. Radiology. 268(1):26-43, 2013
- Lee SH et al: Visceral obesity of the heart: extensive lipomatous hypertrophy of interatrial septum. J Cardiovasc Ultrasound. 20(3):161-2, 2012
- Rigatelli G et al: Anatomo-functional characterization of interatrial septum for catheter-based interventions. Am J Cardiovasc Dis. 1(3):227-35, 2011
- Pugliatti P et al: Lipomatous hypertrophy of the interatrial septum. Int J Cardiol. 130(2):294-5, 2008
- Tugcu A et al: Lipomatous hypertrophy of the interatrial septum presenting as an obstructive right atrial mass in a patient with exertional dyspnea. J Am Soc Echocardiogr. 20(11):1319.e3-5, 2007
- Fan CM et al: Lipomatous hypertrophy of the interatrial septum: increased uptake on FDG PET. AJR Am J Roentgenol. 184(1):339-42, 2005
- Kuester LB et al: Lipomatous hypertrophy of the interatrial septum: prevalence and features on fusion 18F fluorodeoxyglucose positron emission tomography/CT. Chest. 128(6):3888-93, 2005
- Heyer CM et al: Lipomatous hypertrophy of the interatrial septum: a prospective study of incidence, imaging findings, and clinical symptoms. Chest. 124(6):2068-73, 2003
- Iacovoni A et al: [Lipomatous hypertrophy of the interatrial septum: its assessment with TEE, CT and MRI.] G Ital Cardiol. 28(11):1273-7, 1998
- Meaney JF et al: CT appearance of lipomatous hypertrophy of the interatrial septum. AJR Am J Roentgenol. 168(4):1081-4, 1997
- Burke AP et al: Lipomatous hypertrophy of the atrial septum presenting as a right atrial mass. Am J Surg Pathol. 20(6):678-85, 1996
- Shirani J et al: Clinical, electrocardiographic and morphologic features of massive fatty deposits ("lipomatous hypertrophy") in the atrial septum. J Am Coll Cardiol. 22(1):226-38, 1993
- Lund JT et al: Cardiac masses: assessment by MR imaging. AJR Am J Roentgenol. 152(3):469-73, 1989
- Simons M et al: Lipomatous hypertrophy of the atrial septum: diagnosis by combined echocardiography and computerized tomography. Am J Cardiol. 54(3):465-6, 1984
- Prior JT: Lipomatous hypertrophy of cardiac interatrial septum: a lesion resembling hibernoma, lipoblastomatosis and infiltrating lipoma. Arch Pathol. 78:11-5, 1964
