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Lipomatous Uterine Tumors
Douglas Rogers, MD; Christine O. Menias, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Lipomatous uterine tumors (LUT)
          • Definitions

            • Uterine tumors composed, at least in part, of adipose tissue
          • Subtypes

            • Pure lipoma
            • Tumor with lipomatous and mesodermal components
              • Lipoleiomyoma
              • Fibromyolipoma
              • Angiolipoleiomyoma
            • Liposarcoma (extremely rare)

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Drylewicz MR et al: Fatty masses of the abdomen and pelvis and their complications. Abdom Radiol (NY). 44(4):1535-53, 2019
                                          2. Nazir HM et al: Uterine lipoleiomyoma: a report of two cases. J Clin Imaging Sci. 7:26, 2017
                                          3. Terada T: Giant subserosal lipoleiomyomas of the uterine cervix and corpus: a report of 2 cases. Appl Immunohistochem Mol Morphol. 23(2):e1-3, 2015
                                          4. Chu CY et al: Diagnostic challenge of lipomatous uterine tumors in three patients. World J Radiol. 4(2):58-62, 2012
                                          5. Ghosh B et al: Lipoleiomyoma. BMJ Case Rep. 2011, 2011
                                          6. McDonald AG et al: Liposarcoma arising in uterine lipoleiomyoma: a report of 3 cases and review of the literature. Am J Surg Pathol. 35(2):221-7, 2011
                                          7. Terada T: Huge lipoleiomyoma of the uterine cervix. Arch Gynecol Obstet. 283(5):1169-71, 2011
                                          8. Vural C et al: Intravenous lipoleiomyomatosis of uterus with cardiac extension: a case report. Pathol Res Pract. 207(2):131-4, 2011
                                          9. Ding DC et al: Lipoleiomyoma of the uterus. Taiwan J Obstet Gynecol. 49(1):94-6, 2010
                                          10. Manjunatha HK et al: Lipoleiomyoma of uterus in a postmenopausal woman. J Midlife Health. 1(2):86-8, 2010
                                          11. Sudhamani S et al: Lipoleiomyoma of uterus: a case report with review of literature. Indian J Pathol Microbiol. 53(4):840-1, 2010
                                          12. Mignogna C et al: A case of pure uterine lipoma: immunohistochemical and ultrastructural focus. Arch Gynecol Obstet. 2009 Dec;280(6):1071-4. Epub 2009 May 23. Erratum in: Arch Gynecol Obstet. 280(6):1075, 2009
                                          13. Loffroy R et al: Lipoleiomyoma of the uterus: imaging features. Gynecol Obstet Invest. 66(2):73-5, 2008
                                          14. Erdem G et al: Pure uterine lipoma. Magn Reson Imaging. 25(8):1232-6, 2007
                                          15. Fernandes H et al: Pure lipoma of the uterus: a rare case report. Indian J Pathol Microbiol. 50(4):800-1, 2007
                                          16. Kashyap S et al: A rare spectrum of lesions encountered in fibroid uterus: histopathological report. Indian J Pathol Microbiol. 50(4):790-1, 2007
                                          17. Kitajima K et al: MRI findings of uterine lipoleiomyoma correlated with pathologic findings. AJR Am J Roentgenol. 189(2):W100-4, 2007
                                          18. Wang X et al: Uterine lipoleiomyomas: a clinicopathologic study of 50 cases. Int J Gynecol Pathol. 25(3):239-42, 2006
                                          19. Aslan E et al: Lipoleiomyoma of the uterus: a diagnostic problem. J Obstet Gynaecol. 25(6):610-1, 2005
                                          20. Lau LU et al: Case report. Uterine lipoma: advantage of MRI over ultrasound. Br J Radiol. 78(925):72-4, 2005
                                          21. Maebayashi T et al: Radiologic features of uterine lipoleiomyoma. J Comput Assist Tomogr. 27(2):162-5, 2003
                                          22. Avritscher R et al: Lipoleiomyoma of the uterus. AJR Am J Roentgenol. 177(4):856, 2001
                                          23. Prieto A et al: Uterine lipoleiomyomas: US and CT findings. Abdom Imaging. 25(6):655-7, 2000
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Lipomatous uterine tumors (LUT)
                                                  • Definitions

                                                    • Uterine tumors composed, at least in part, of adipose tissue
                                                  • Subtypes

                                                    • Pure lipoma
                                                    • Tumor with lipomatous and mesodermal components
                                                      • Lipoleiomyoma
                                                      • Fibromyolipoma
                                                      • Angiolipoleiomyoma
                                                    • Liposarcoma (extremely rare)

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Drylewicz MR et al: Fatty masses of the abdomen and pelvis and their complications. Abdom Radiol (NY). 44(4):1535-53, 2019
                                                                                  2. Nazir HM et al: Uterine lipoleiomyoma: a report of two cases. J Clin Imaging Sci. 7:26, 2017
                                                                                  3. Terada T: Giant subserosal lipoleiomyomas of the uterine cervix and corpus: a report of 2 cases. Appl Immunohistochem Mol Morphol. 23(2):e1-3, 2015
                                                                                  4. Chu CY et al: Diagnostic challenge of lipomatous uterine tumors in three patients. World J Radiol. 4(2):58-62, 2012
                                                                                  5. Ghosh B et al: Lipoleiomyoma. BMJ Case Rep. 2011, 2011
                                                                                  6. McDonald AG et al: Liposarcoma arising in uterine lipoleiomyoma: a report of 3 cases and review of the literature. Am J Surg Pathol. 35(2):221-7, 2011
                                                                                  7. Terada T: Huge lipoleiomyoma of the uterine cervix. Arch Gynecol Obstet. 283(5):1169-71, 2011
                                                                                  8. Vural C et al: Intravenous lipoleiomyomatosis of uterus with cardiac extension: a case report. Pathol Res Pract. 207(2):131-4, 2011
                                                                                  9. Ding DC et al: Lipoleiomyoma of the uterus. Taiwan J Obstet Gynecol. 49(1):94-6, 2010
                                                                                  10. Manjunatha HK et al: Lipoleiomyoma of uterus in a postmenopausal woman. J Midlife Health. 1(2):86-8, 2010
                                                                                  11. Sudhamani S et al: Lipoleiomyoma of uterus: a case report with review of literature. Indian J Pathol Microbiol. 53(4):840-1, 2010
                                                                                  12. Mignogna C et al: A case of pure uterine lipoma: immunohistochemical and ultrastructural focus. Arch Gynecol Obstet. 2009 Dec;280(6):1071-4. Epub 2009 May 23. Erratum in: Arch Gynecol Obstet. 280(6):1075, 2009
                                                                                  13. Loffroy R et al: Lipoleiomyoma of the uterus: imaging features. Gynecol Obstet Invest. 66(2):73-5, 2008
                                                                                  14. Erdem G et al: Pure uterine lipoma. Magn Reson Imaging. 25(8):1232-6, 2007
                                                                                  15. Fernandes H et al: Pure lipoma of the uterus: a rare case report. Indian J Pathol Microbiol. 50(4):800-1, 2007
                                                                                  16. Kashyap S et al: A rare spectrum of lesions encountered in fibroid uterus: histopathological report. Indian J Pathol Microbiol. 50(4):790-1, 2007
                                                                                  17. Kitajima K et al: MRI findings of uterine lipoleiomyoma correlated with pathologic findings. AJR Am J Roentgenol. 189(2):W100-4, 2007
                                                                                  18. Wang X et al: Uterine lipoleiomyomas: a clinicopathologic study of 50 cases. Int J Gynecol Pathol. 25(3):239-42, 2006
                                                                                  19. Aslan E et al: Lipoleiomyoma of the uterus: a diagnostic problem. J Obstet Gynaecol. 25(6):610-1, 2005
                                                                                  20. Lau LU et al: Case report. Uterine lipoma: advantage of MRI over ultrasound. Br J Radiol. 78(925):72-4, 2005
                                                                                  21. Maebayashi T et al: Radiologic features of uterine lipoleiomyoma. J Comput Assist Tomogr. 27(2):162-5, 2003
                                                                                  22. Avritscher R et al: Lipoleiomyoma of the uterus. AJR Am J Roentgenol. 177(4):856, 2001
                                                                                  23. Prieto A et al: Uterine lipoleiomyomas: US and CT findings. Abdom Imaging. 25(6):655-7, 2000