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Liposclerosing Myxofibrous Tumor
B.J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Liposclerosing myxofibrous tumor (LSMFT)
          • Synonyms

            • Polymorphic fibrocystic disease of bone, polymorphic fibroosseous lesion of bone
          • Definitions

            • Benign fibroosseous lesion, typified by propensity to occur in intertrochanteric region

          IMAGING

          • General Features

            • Imaging Recommendations

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        Selected References

                                        1. Dattilo J et al: Liposclerosing myxofibrous tumor (LSMFT), a study of 33 patients: should it be a distinct entity? Iowa Orthop J. 32:35-9, 2012
                                        2. Campbell K et al: Case report: two-step malignant transformation of a liposclerosing myxofibrous tumor of bone. Clin Orthop Relat Res. 466(11):2873-7, 2008
                                        3. Heim-Hall JM et al: Liposclerosing myxofibrous tumour: a traumatized variant of fibrous dysplasia? Report of four cases and review of the literature. Histopathology. 45(4):369-76, 2004
                                        4. Kransdorf MJ et al: Liposclerosing myxofibrous tumor: a radiologic-pathologic-distinct fibro-osseous lesion of bone with a marked predilection for the intertrochanteric region of the femur. Radiology. 212(3):693-8, 1999
                                        5. Gilkey FW: Liposclerosing myxofibrous tumor of bone. Hum Pathol. 24(11):1264, 1993
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Liposclerosing myxofibrous tumor (LSMFT)
                                                • Synonyms

                                                  • Polymorphic fibrocystic disease of bone, polymorphic fibroosseous lesion of bone
                                                • Definitions

                                                  • Benign fibroosseous lesion, typified by propensity to occur in intertrochanteric region

                                                IMAGING

                                                • General Features

                                                  • Imaging Recommendations

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Nuclear Medicine Findings

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Gross Pathologic & Surgical Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              Selected References

                                                                              1. Dattilo J et al: Liposclerosing myxofibrous tumor (LSMFT), a study of 33 patients: should it be a distinct entity? Iowa Orthop J. 32:35-9, 2012
                                                                              2. Campbell K et al: Case report: two-step malignant transformation of a liposclerosing myxofibrous tumor of bone. Clin Orthop Relat Res. 466(11):2873-7, 2008
                                                                              3. Heim-Hall JM et al: Liposclerosing myxofibrous tumour: a traumatized variant of fibrous dysplasia? Report of four cases and review of the literature. Histopathology. 45(4):369-76, 2004
                                                                              4. Kransdorf MJ et al: Liposclerosing myxofibrous tumor: a radiologic-pathologic-distinct fibro-osseous lesion of bone with a marked predilection for the intertrochanteric region of the femur. Radiology. 212(3):693-8, 1999
                                                                              5. Gilkey FW: Liposclerosing myxofibrous tumor of bone. Hum Pathol. 24(11):1264, 1993