Autosomal dominant connective tissue disorder with aortic/arterial abnormalities
IMAGING
General Features
CT Findings
MR Findings
Echocardiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
Selected References
Iqbal R et al: Loeys-Dietz syndrome pathology and aspects of cardiovascular management: a systematic review. Vascular. 29(1):3-14, 2021
Estrera AL: Loeys-Dietz syndrome: we have come a (Fur)long way. J Thorac Cardiovasc Surg. 157(2):453-54, 2019
Jud P et al: Vascular involvement in Loeys-Dietz syndrome. Mayo Clin Proc. 94(6):1117-9, 2019
Loughborough WW et al: Cardiovascular manifestations and complications of Loeys-Dietz syndrome: CT and MR imaging findings. Radiographics. 38(1):275-86, 2018
Gawinecka J et al: Acute aortic dissection: pathogenesis, risk factors and diagnosis. Swiss Med Wkly. 147:w14489, 2017
Meester JAN et al: Differences in manifestations of Marfan syndrome, Ehlers-Danlos syndrome, and Loeys-Dietz syndrome. Ann Cardiothorac Surg. 6(6):582-94, 2017
Hanneman K et al: Pre- and postoperative imaging of the aortic root. Radiographics. 36(1):19-37, 2016
Agrawal A et al: Spontaneous coronary artery dissection in Loeys-Dietz syndrome: role of optical coherence tomography in diagnosis and management. J Invasive Cardiol. 27(9):E196-8, 2015
Beckmann E et al: Surgical experience in a patient with Loeys-Dietz syndrome type I. Ann Thorac Surg. 97(5):e125-7, 2014
Chu LC et al: CT angiographic evaluation of genetic vascular disease: role in detection, staging, and management of complex vascular pathologic conditions. AJR Am J Roentgenol. 202(5):1120-9, 2014
Morgan GJ et al: Imaging and percutaneous occlusion of a large aneurysm of the ductus arteriosus in an infant with Loeys-Dietz syndrome. Congenit Heart Dis. 8(6):E192-5, 2013
Dhouib A et al: Imaging findings in a child with Loeys-Dietz syndrome. Circulation. 126(4):507-8, 2012
Hughes GC: Aggressive aortic replacement for Loeys-Dietz syndrome. Tex Heart Inst J. 38(6):663-6, 2011
Autosomal dominant connective tissue disorder with aortic/arterial abnormalities
IMAGING
General Features
CT Findings
MR Findings
Echocardiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
Selected References
Iqbal R et al: Loeys-Dietz syndrome pathology and aspects of cardiovascular management: a systematic review. Vascular. 29(1):3-14, 2021
Estrera AL: Loeys-Dietz syndrome: we have come a (Fur)long way. J Thorac Cardiovasc Surg. 157(2):453-54, 2019
Jud P et al: Vascular involvement in Loeys-Dietz syndrome. Mayo Clin Proc. 94(6):1117-9, 2019
Loughborough WW et al: Cardiovascular manifestations and complications of Loeys-Dietz syndrome: CT and MR imaging findings. Radiographics. 38(1):275-86, 2018
Gawinecka J et al: Acute aortic dissection: pathogenesis, risk factors and diagnosis. Swiss Med Wkly. 147:w14489, 2017
Meester JAN et al: Differences in manifestations of Marfan syndrome, Ehlers-Danlos syndrome, and Loeys-Dietz syndrome. Ann Cardiothorac Surg. 6(6):582-94, 2017
Hanneman K et al: Pre- and postoperative imaging of the aortic root. Radiographics. 36(1):19-37, 2016
Agrawal A et al: Spontaneous coronary artery dissection in Loeys-Dietz syndrome: role of optical coherence tomography in diagnosis and management. J Invasive Cardiol. 27(9):E196-8, 2015
Beckmann E et al: Surgical experience in a patient with Loeys-Dietz syndrome type I. Ann Thorac Surg. 97(5):e125-7, 2014
Chu LC et al: CT angiographic evaluation of genetic vascular disease: role in detection, staging, and management of complex vascular pathologic conditions. AJR Am J Roentgenol. 202(5):1120-9, 2014
Morgan GJ et al: Imaging and percutaneous occlusion of a large aneurysm of the ductus arteriosus in an infant with Loeys-Dietz syndrome. Congenit Heart Dis. 8(6):E192-5, 2013
Dhouib A et al: Imaging findings in a child with Loeys-Dietz syndrome. Circulation. 126(4):507-8, 2012
Hughes GC: Aggressive aortic replacement for Loeys-Dietz syndrome. Tex Heart Inst J. 38(6):663-6, 2011