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Lymphangioma
Karen Y. Oh, MD; Roya Sohaey, MD
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Clinical Issues

        • Diagnostic Checklist

          TERMINOLOGY

          • Synonyms

            • Cystic lymphangioma (CL)
            • Nonnuchal cystic hygroma
            • Axillary lymphangioma
            • Cutaneous lymphangioma
          • Definitions

            • Benign, nonnuchal, cystic tumors of lymphatic system

          IMAGING

          • General Features

            • Ultrasonographic Findings

              • MR Findings

                • Imaging Recommendations

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Gross Pathologic & Surgical Features

                        • Microscopic Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Arisoy R et al: Prenatal diagnosis and outcome of lymphangiomas and its relationship with fetal chromosomal abnormalities. J Matern Fetal Neonatal Med. 1-7, 2015
                                      2. Koelblinger C et al: Fetal magnetic resonance imaging of lymphangiomas. J Perinat Med. 41(4):437-43, 2013
                                      3. Surico D et al: Antenatal diagnosis of fetal lymphangioma by ultrasonography. Eur J Obstet Gynecol Reprod Biol. 168(2):236, 2013
                                      4. Chiappinelli A et al: Congenital abdominal cystic lymphangiomas: what is the correct management? J Matern Fetal Neonatal Med. 25(7):915-9, 2012
                                      5. Wiegand S et al: Sclerotherapy of lymphangiomas of the head and neck. Head Neck. 33(11):1649-55, 2011
                                      6. Cozzi DA et al: Fetal abdominal lymphangioma enhanced by ultrafast MRI. Fetal Diagn Ther. 27(1):46-50, 2010
                                      7. Mikovic Z et al: Intrauterine treatment of large fetal neck lymphangioma with OK-432. Fetal Diagn Ther. 26(2):102-6, 2009
                                      8. Pascoli I et al: EXIT (Ex Utero Intrapartum Treatment) technique - Management of a giant fetal lymphangioma. J Matern Fetal Neonatal Med. Epub ahead of print, 2009
                                      9. Hachisuga M et al: Prenatal diagnosis of a retroperitoneal lymphangioma: a case and review. Fetal Diagn Ther. 24(3):177-81, 2008
                                      10. Langer JE et al: Extensive fetal abdominopelvic lymphangioma. Ultrasound Q. 24(2):115-9, 2008
                                      11. Goldstein I et al: Prenatal diagnosis of fetal chest lymphangioma. J Ultrasound Med. 25(11):1437-40, 2006
                                      12. York DG et al: Fetal abdomino-perineal lymphangioma: differential diagnosis and management. Prenat Diagn. 26(8):692-5, 2006
                                      13. Chiaverini C et al: Prenatal ultrasonographic detection of an axillo-thoracic lymphangioma: an ethical dilemma. Prenat Diagn. 23(11):946-8, 2003
                                      14. Ruano R et al: Prenatal diagnosis of a large axillary cystic lymphangioma by three-dimensional ultrasonography and magnetic resonance imaging. J Ultrasound Med. 22(4):419-23, 2003
                                      15. Ho M et al: Prenatal diagnosis of abdominal lymphangioma. Ultrasound Obstet Gynecol. 20(2):205-6, 2002
                                      16. Deshpande P et al: Prenatal diagnosis of fetal abdominal lymphangioma by ultrasonography. Ultrasound Obstet Gynecol. 17(5):445-8, 2001
                                      17. Zanotti SD et al: Prenatal sonographic diagnosis of axillary cystic lymphangiomas. J Clin Ultrasound. 29(2):112-5, 2001
                                      18. McCoy MC et al: Prenatal diagnosis and management of massive bilateral axillary cystic lymphangioma. Obstet Gynecol. 85(5 Pt 2):853-6, 1995
                                      19. Reichler A et al: Early prenatal diagnosis of axillary cystic hygroma. J Ultrasound Med. 14(8):581-4, 1995
                                      20. Fonkalsrud EW: Congenital malformations of the lymphatic system. Semin Pediatr Surg. 3(2):62-9, 1994
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Clinical Issues

                                            • Diagnostic Checklist

                                              TERMINOLOGY

                                              • Synonyms

                                                • Cystic lymphangioma (CL)
                                                • Nonnuchal cystic hygroma
                                                • Axillary lymphangioma
                                                • Cutaneous lymphangioma
                                              • Definitions

                                                • Benign, nonnuchal, cystic tumors of lymphatic system

                                              IMAGING

                                              • General Features

                                                • Ultrasonographic Findings

                                                  • MR Findings

                                                    • Imaging Recommendations

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • General Features

                                                          • Gross Pathologic & Surgical Features

                                                            • Microscopic Features

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      DIAGNOSTIC CHECKLIST

                                                                      • Consider

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Arisoy R et al: Prenatal diagnosis and outcome of lymphangiomas and its relationship with fetal chromosomal abnormalities. J Matern Fetal Neonatal Med. 1-7, 2015
                                                                          2. Koelblinger C et al: Fetal magnetic resonance imaging of lymphangiomas. J Perinat Med. 41(4):437-43, 2013
                                                                          3. Surico D et al: Antenatal diagnosis of fetal lymphangioma by ultrasonography. Eur J Obstet Gynecol Reprod Biol. 168(2):236, 2013
                                                                          4. Chiappinelli A et al: Congenital abdominal cystic lymphangiomas: what is the correct management? J Matern Fetal Neonatal Med. 25(7):915-9, 2012
                                                                          5. Wiegand S et al: Sclerotherapy of lymphangiomas of the head and neck. Head Neck. 33(11):1649-55, 2011
                                                                          6. Cozzi DA et al: Fetal abdominal lymphangioma enhanced by ultrafast MRI. Fetal Diagn Ther. 27(1):46-50, 2010
                                                                          7. Mikovic Z et al: Intrauterine treatment of large fetal neck lymphangioma with OK-432. Fetal Diagn Ther. 26(2):102-6, 2009
                                                                          8. Pascoli I et al: EXIT (Ex Utero Intrapartum Treatment) technique - Management of a giant fetal lymphangioma. J Matern Fetal Neonatal Med. Epub ahead of print, 2009
                                                                          9. Hachisuga M et al: Prenatal diagnosis of a retroperitoneal lymphangioma: a case and review. Fetal Diagn Ther. 24(3):177-81, 2008
                                                                          10. Langer JE et al: Extensive fetal abdominopelvic lymphangioma. Ultrasound Q. 24(2):115-9, 2008
                                                                          11. Goldstein I et al: Prenatal diagnosis of fetal chest lymphangioma. J Ultrasound Med. 25(11):1437-40, 2006
                                                                          12. York DG et al: Fetal abdomino-perineal lymphangioma: differential diagnosis and management. Prenat Diagn. 26(8):692-5, 2006
                                                                          13. Chiaverini C et al: Prenatal ultrasonographic detection of an axillo-thoracic lymphangioma: an ethical dilemma. Prenat Diagn. 23(11):946-8, 2003
                                                                          14. Ruano R et al: Prenatal diagnosis of a large axillary cystic lymphangioma by three-dimensional ultrasonography and magnetic resonance imaging. J Ultrasound Med. 22(4):419-23, 2003
                                                                          15. Ho M et al: Prenatal diagnosis of abdominal lymphangioma. Ultrasound Obstet Gynecol. 20(2):205-6, 2002
                                                                          16. Deshpande P et al: Prenatal diagnosis of fetal abdominal lymphangioma by ultrasonography. Ultrasound Obstet Gynecol. 17(5):445-8, 2001
                                                                          17. Zanotti SD et al: Prenatal sonographic diagnosis of axillary cystic lymphangiomas. J Clin Ultrasound. 29(2):112-5, 2001
                                                                          18. McCoy MC et al: Prenatal diagnosis and management of massive bilateral axillary cystic lymphangioma. Obstet Gynecol. 85(5 Pt 2):853-6, 1995
                                                                          19. Reichler A et al: Early prenatal diagnosis of axillary cystic hygroma. J Ultrasound Med. 14(8):581-4, 1995
                                                                          20. Fonkalsrud EW: Congenital malformations of the lymphatic system. Semin Pediatr Surg. 3(2):62-9, 1994