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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Lymphangitic carcinomatosis (LC)
Synonyms
- Lymphangitic spread
Definitions
- Infiltration of lymphatic channels by tumor emboli (common) or direct retrograde spread from affected hilar lymph nodes
- LC results primarily from adenocarcinomas (80%)
- Lung
- Breast
- Other: Stomach, colon, pancreas, prostate
- Involvement of lymphatic channels in interlobular and subpleural interstitium (i.e., peripheral interstitium) &/or central lymphatic channels in bronchovascular and centrilobular interstitium (i.e., axial interstitium)
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Diagnosis
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
- AK AK et al: Lymphangitic Carcinomatosis 2020
- Jreige M et al: Pulmonary lymphangitic carcinomatosis: diagnostic performance of high-resolution CT and 18F-FDG PET/CT in correlation with clinical pathologic outcome. J Nucl Med. 61(1):26-32, 2020
- Klimek M: Pulmonary lymphangitis carcinomatosis: systematic review and meta-analysis of case reports, 1970-2018. Postgrad Med. 131(5):309-18, 2019
- Mendoza DP et al: The added value of quantitative 18F-FDG-PET/CT parameters in the assessment of pulmonary lymphangitic carcinomatosis in lung cancer. J Thorac Dis. 11(11):E239-42, 2019
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Lymphangitic carcinomatosis (LC)
Synonyms
- Lymphangitic spread
Definitions
- Infiltration of lymphatic channels by tumor emboli (common) or direct retrograde spread from affected hilar lymph nodes
- LC results primarily from adenocarcinomas (80%)
- Lung
- Breast
- Other: Stomach, colon, pancreas, prostate
- Involvement of lymphatic channels in interlobular and subpleural interstitium (i.e., peripheral interstitium) &/or central lymphatic channels in bronchovascular and centrilobular interstitium (i.e., axial interstitium)
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Diagnosis
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
- AK AK et al: Lymphangitic Carcinomatosis 2020
- Jreige M et al: Pulmonary lymphangitic carcinomatosis: diagnostic performance of high-resolution CT and 18F-FDG PET/CT in correlation with clinical pathologic outcome. J Nucl Med. 61(1):26-32, 2020
- Klimek M: Pulmonary lymphangitis carcinomatosis: systematic review and meta-analysis of case reports, 1970-2018. Postgrad Med. 131(5):309-18, 2019
- Mendoza DP et al: The added value of quantitative 18F-FDG-PET/CT parameters in the assessment of pulmonary lymphangitic carcinomatosis in lung cancer. J Thorac Dis. 11(11):E239-42, 2019
