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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Lymphangitic carcinomatosis (LC)
Synonyms
Lymphangitic spread
Definitions
Infiltration of lymphatic channels by tumor emboli (common) or direct retrograde spread from affected hilar lymph nodes
LC results primarily from adenocarcinomas (80%)
Lung
Breast
Other: Stomach, colon, pancreas, prostate
Involvement of lymphatic channels in interlobular and subpleural interstitium (i.e., peripheral interstitium) &/or central lymphatic channels in bronchovascular and centrilobular interstitium (i.e., axial interstitium)
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Diagnosis
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
AK AK et al: Lymphangitic Carcinomatosis 2020
Jreige M et al: Pulmonary lymphangitic carcinomatosis: diagnostic performance of high-resolution CT and 18F-FDG PET/CT in correlation with clinical pathologic outcome. J Nucl Med. 61(1):26-32, 2020
Klimek M: Pulmonary lymphangitis carcinomatosis: systematic review and meta-analysis of case reports, 1970-2018. Postgrad Med. 131(5):309-18, 2019
Mendoza DP et al: The added value of quantitative 18F-FDG-PET/CT parameters in the assessment of pulmonary lymphangitic carcinomatosis in lung cancer. J Thorac Dis. 11(11):E239-42, 2019
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Lymphangitic carcinomatosis (LC)
Synonyms
Lymphangitic spread
Definitions
Infiltration of lymphatic channels by tumor emboli (common) or direct retrograde spread from affected hilar lymph nodes
LC results primarily from adenocarcinomas (80%)
Lung
Breast
Other: Stomach, colon, pancreas, prostate
Involvement of lymphatic channels in interlobular and subpleural interstitium (i.e., peripheral interstitium) &/or central lymphatic channels in bronchovascular and centrilobular interstitium (i.e., axial interstitium)
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Diagnosis
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
AK AK et al: Lymphangitic Carcinomatosis 2020
Jreige M et al: Pulmonary lymphangitic carcinomatosis: diagnostic performance of high-resolution CT and 18F-FDG PET/CT in correlation with clinical pathologic outcome. J Nucl Med. 61(1):26-32, 2020
Klimek M: Pulmonary lymphangitis carcinomatosis: systematic review and meta-analysis of case reports, 1970-2018. Postgrad Med. 131(5):309-18, 2019
Mendoza DP et al: The added value of quantitative 18F-FDG-PET/CT parameters in the assessment of pulmonary lymphangitic carcinomatosis in lung cancer. J Thorac Dis. 11(11):E239-42, 2019
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