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Lymphoma
Jeffrey S. Ross, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Definitions

            • Lymphoreticular neoplasms with myriad of specific diseases and cellular differentiation

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          Selected References

                                          1. Dada R: Diagnosis and management of follicular lymphoma: a comprehensive review. Eur J Haematol. 103(3):152-63, 2019
                                          2. Liu Y et al: Diffuse large B-cell lymphoma: 2019 update on diagnosis, risk stratification, and treatment. Am J Hematol. 94(5):604-16, 2019
                                          3. Becnel MR et al: Follicular lymphoma: past, present, and future. Curr Treat Options Oncol. 19(7):32, 2018
                                          4. Mechtler LL et al: Spinal cord tumors: new views and future directions. Neurol Clin. 31(1):241-68, 2013
                                          5. Hanrahan CJ et al: MRI of spinal bone marrow: part 2, T1-weighted imaging-based differential diagnosis. AJR Am J Roentgenol. 197(6):1309-21, 2011
                                          6. Barajas RF Jr et al: Diffusion-weighted MR imaging derived apparent diffusion coefficient is predictive of clinical outcome in primary central nervous system lymphoma. AJNR Am J Neuroradiol. 31(1):60-6, 2010
                                          7. Geus-Oei LF et al: Predictive and prognostic value of FDG-PET. Cancer Imaging. 8:70-80, 2008
                                          8. Schroeder PC et al: Analysis of the utility of diffusion-weighted MRI and apparent diffusion coefficient values in distinguishing central nervous system toxoplasmosis from lymphoma. Neuroradiology. 48(10):715-20, 2006
                                          9. Legeais M et al: Paraplegia and sensory deficit caused by angiotropic large cell lymphoma. AJNR Am J Neuroradiol. 25(10):1831-5, 2004
                                          10. Westin EH et al: Lymphoma and myeloma in older patients. Semin Oncol. 31(2):198-205, 2004
                                          11. Rahmouni A et al: Bone marrow with diffuse tumor infiltration in patients with lymphoproliferative diseases: dynamic gadolinium-enhanced MR imaging. Radiology. 229(3):710-7, 2003
                                          12. Israel O et al: Bone lymphoma: 67Ga scintigraphy and CT for prediction of outcome after treatment. J Nucl Med. 43(10):1295-303, 2002
                                          13. Vazquez E et al: Neuroimaging in pediatric leukemia and lymphoma: differential diagnosis. Radiographics. 22(6):1411-28, 2002
                                          14. Guermazi A et al: Extranodal Hodgkin disease: spectrum of disease. Radiographics. 21(1):161-79, 2001
                                          15. Koeller KK et al: Neoplasms of the spinal cord and filum terminale: radiologic-pathologic correlation. Radiographics. 20(6):1721-49, 2000
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Definitions

                                                    • Lymphoreticular neoplasms with myriad of specific diseases and cellular differentiation

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Nuclear Medicine Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Staging, Grading, & Classification

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  Selected References

                                                                                  1. Dada R: Diagnosis and management of follicular lymphoma: a comprehensive review. Eur J Haematol. 103(3):152-63, 2019
                                                                                  2. Liu Y et al: Diffuse large B-cell lymphoma: 2019 update on diagnosis, risk stratification, and treatment. Am J Hematol. 94(5):604-16, 2019
                                                                                  3. Becnel MR et al: Follicular lymphoma: past, present, and future. Curr Treat Options Oncol. 19(7):32, 2018
                                                                                  4. Mechtler LL et al: Spinal cord tumors: new views and future directions. Neurol Clin. 31(1):241-68, 2013
                                                                                  5. Hanrahan CJ et al: MRI of spinal bone marrow: part 2, T1-weighted imaging-based differential diagnosis. AJR Am J Roentgenol. 197(6):1309-21, 2011
                                                                                  6. Barajas RF Jr et al: Diffusion-weighted MR imaging derived apparent diffusion coefficient is predictive of clinical outcome in primary central nervous system lymphoma. AJNR Am J Neuroradiol. 31(1):60-6, 2010
                                                                                  7. Geus-Oei LF et al: Predictive and prognostic value of FDG-PET. Cancer Imaging. 8:70-80, 2008
                                                                                  8. Schroeder PC et al: Analysis of the utility of diffusion-weighted MRI and apparent diffusion coefficient values in distinguishing central nervous system toxoplasmosis from lymphoma. Neuroradiology. 48(10):715-20, 2006
                                                                                  9. Legeais M et al: Paraplegia and sensory deficit caused by angiotropic large cell lymphoma. AJNR Am J Neuroradiol. 25(10):1831-5, 2004
                                                                                  10. Westin EH et al: Lymphoma and myeloma in older patients. Semin Oncol. 31(2):198-205, 2004
                                                                                  11. Rahmouni A et al: Bone marrow with diffuse tumor infiltration in patients with lymphoproliferative diseases: dynamic gadolinium-enhanced MR imaging. Radiology. 229(3):710-7, 2003
                                                                                  12. Israel O et al: Bone lymphoma: 67Ga scintigraphy and CT for prediction of outcome after treatment. J Nucl Med. 43(10):1295-303, 2002
                                                                                  13. Vazquez E et al: Neuroimaging in pediatric leukemia and lymphoma: differential diagnosis. Radiographics. 22(6):1411-28, 2002
                                                                                  14. Guermazi A et al: Extranodal Hodgkin disease: spectrum of disease. Radiographics. 21(1):161-79, 2001
                                                                                  15. Koeller KK et al: Neoplasms of the spinal cord and filum terminale: radiologic-pathologic correlation. Radiographics. 20(6):1721-49, 2000